Volume 14, Issue 5 (5-2016)                   IJRM 2016, 14(5): 335-340 | Back to browse issues page

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Minooee S, Ramezani Tehrani F, Mirmiran P, Azizi F. Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome. IJRM 2016; 14 (5) :335-340
URL: http://ijrm.ir/article-1-746-en.html
Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
Sonia Minooee1 , Fahimeh Ramezani Tehrani * 2, Parvin Mirmiran3 , Fereidoun Azizi4
1- Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran , ramezani@endocrine.ac.ir
3- Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (2697 Views)
Background: Women engaged with polycystic ovarian syndrome (PCOS), as the commonest endocrine disorder, are known to have a specific type of adiposity. Birth weight is among different contributors reported to be responsible for this diversity.
Objective: We aimed to compare the relation between birth weight and body fat mass (BFM)/ body lean mass (BLM) in PCOS and their age and body mass index (BMI) matched normal controls.
Materials and Methods: In this case-control study, a total number of 70 reproductive aged women, diagnosed with PCOS and 70 age- BMI matched healthy women without hirsutism and/or ovulatory dysfunction were recruited., control group had no polycystic ovaries in ultrasonographic scans. A detailed history of birth weight was taken and was divided into the following categories: <2,500 (low birth weight, LBW) and 2,500-4,000 (normal birth weight; NBW).
Results: Results showed that LBW prevalence was higher in women with PCOS than in controls (19.3% (27) vs. 15.7% (22)). Also body fat and lean mass (BFM, BLM) have increased in adult women with PCOS who were born underweight compared to their normal (19.8±9.05 vs. 12.9±4.5, p=0.001 and 48.9±6.9 vs. 43.2±5.8, p=0.004 respectively).
Conclusion: Fetal birth weight influences on the adulthood obesity, BFM and BLM. This impact is different among women with and without PCOS.
Keywords: Body fat mass, Body lean mass, Birth weight, Poly cystic ovarian syndrome
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Type of Study: Original Article |
References
1. Franks S, McCarthy MI, Hardy K. Development of polycystic ovary syndrome: involvement of genetic and environmental factors. Int J Androl 2006; 29: 278-285. [DOI:10.1111/j.1365-2605.2005.00623.x]
2. Abbott DH, Barnett DK, Bruns CM, Dumesic DA. Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome? Hum Reprod Update 2005; 11: 357-374. [DOI:10.1093/humupd/dmi013]
3. Carmina E, Bucchieri S, Esposito A, Del Puente A, Mansueto P, Orio F, et al. Abdominal fat quantity and distribution in women with polycystic ovary syndrome and extent of its relation to insulin resistance. J Clin Endocrinol Metab 2007; 92: 2500-2505. [DOI:10.1210/jc.2006-2725]
4. Barber TM, Golding SJ, Alvey C, Wass JA, Karpe F, Franks S, et al. Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome. J Clin Endocrinol Metab 2008; 93: 999-1004. [DOI:10.1210/jc.2007-2117]
5. Lord J, Thomas R, Fox B, Acharya U, Wilkin T. The central issue? Visceral fat mass is a good marker of insulin resistance and metabolic disturbance in women with polycystic ovary syndrome. Br J Obstet Gynaecol 2006; 113: 1203-1209. [DOI:10.1111/j.1471-0528.2006.00973.x]
6. Borruel S, Fernandez-Duran E, Alpanes M, Marti D, Alvarez-Blasco F, Luque-Ramirez M, et al. Global adiposity and thickness of intraperitoneal and mesenteric adipose tissue depots are increased in women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab 2013; 98: 1254-1263. [DOI:10.1210/jc.2012-3698]
7. Wang ET, Calderon-Margalit R, Cedars MI, Daviglus ML, Merkin SS, Schreiner PJ, et al. Polycystic ovary syndrome and risk for long-term diabetes and dyslipidemia. Obstet Gynecol 2011; 117: 6-13. [DOI:10.1097/AOG.0b013e31820209bb]
8. Kim JJ, Choi YM. Dyslipidemia in women with polycystic ovary syndrome. Obstet Gynecol Sci 2013; 56: 137-142. [DOI:10.5468/ogs.2013.56.3.137]
9. Zabuliene L, Tutkuviene J. [Body composition and polycystic ovary syndrome]. Medicina (Kaunas, Lithuania) 2010; 46: 142-157. (In Lithuanian)
10. Sarr O, Yang K, Regnault TR. In utero programming of later adiposity: the role of fetal growth restriction. Pregnancy 2012; 2012: 134758.
11. Binkin NJ, Yip R, Fleshood L, Trowbridge FL. Birth weight and childhood growth. Pediatr 1988; 82: 828-834.
12. Schroeder DG, Martorell R. Fatness and body mass index from birth to young adulthood in a rural Guatemalan population. Am J Clin Nutr 1999; 70: 137s-144s.
13. Hediger ML, Overpeck MD, Kuczmarski RJ, McGlynn A, Maurer KR, Davis WW. Muscularity and fatness of infants and young children born small-or large-for-gestational-age. Pediatr 1998; 102: e60. [DOI:10.1542/peds.102.5.e60]
14. Adair LS, Gordon-Larsen P. A Study of the Birth Weight–Obesity Relation Using a Longitudinal Cohort and Sibling and Twin Pairs. Am J Epidemiol 2010; 172: 549-557. [DOI:10.1093/aje/kwq169]
15. Kirchengast S, Huber J. Body composition characteristics and body fat distribution in lean women with polycystic ovary syndrome. Hum Reprod 2001; 16: 1255-1260. [DOI:10.1093/humrep/16.6.1255]
16. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81: 19-25. [DOI:10.1016/j.fertnstert.2003.10.004]
17. Tehrani FR, Simbar M, Tohidi M, Hosseinpanah F, Azizi F. The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reprod Biol Endocrinol 2011; 9: 39. [DOI:10.1186/1477-7827-9-39]
18. Nijland MJ, Ford SP, Nathanielsz PW. Prenatal origins of adult disease. Curr Opin Obstet Gynecol 2008; 20: 132-138. [DOI:10.1097/GCO.0b013e3282f76753]
19. Remacle C, Bieswal F, Bol V, Reusens B. Developmental programming of adult obesity and cardiovascular disease in rodents by maternal nutrition imbalance. Am J Clin Nutr 2011; 94 (Suppl.): 1846S-1852S. [DOI:10.3945/ajcn.110.001651]
20. Barker DJ, Bull AR, Osmond C, Simmonds SJ. Fetal and placental size and risk of hypertension in adult life. Br Med J 1990; 301: 259-262. [DOI:10.1136/bmj.301.6746.259]
21. Ibá-ez L, Ong K, Dunger DB, de Zegher F. Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab 2006; 91: 2153-2158. [DOI:10.1210/jc.2005-2778]
22. de Zegher F, Lopez-Bermejo A, Ibanez L. Adipose tissue expandability and the early origins of PCOS. Trends Endocrinol Metab 2009; 20: 418-423. [DOI:10.1016/j.tem.2009.06.003]
23. Carmina E, Guastella E, Longo RA, Rini GB, Lobo RA. Correlates of increased lean muscle mass in women with polycystic ovary syndrome. Euro J Endocrinol 2009; 161: 583-589. [DOI:10.1530/EJE-09-0398]
24. Douchi T, Oki T, Yamasaki H, Kuwahata R, Nakae M, Nagata Y. Relationship of androgens to muscle size and bone mineral density in women with polycystic ovary syndrome. Obstet Gynecol 2001; 98: 445-449.
25. Kirchengast S, Huber J. Body composition characteristics and body fat distribution in lean women with polycystic ovary syndrome. Hum Reprod 2001; 16: 1255-1260. [DOI:10.1093/humrep/16.6.1255]
26. Jaiswal M, Crume T, Vehik K, Scherzinger A, Stamm E, Hamman RF, et al. Is low birth weight associated with adiposity in contemporary U.S. youth? The Exploring Perinatal Outcomes among Children (EPOCH) Study. J Dev Orig Health Dis 2012; 3: 166-1672. [DOI:10.1017/S2040174412000165]
27. Mathew V, Ayyar SV. Developmental origins of adult diseases. Indian J Endocrinol Metab 2012; 16: 532-541. [DOI:10.4103/2230-8210.98005]
28. Aydin K, Cinar N, Aksoy DY, Bozdag G, Yildiz BO.Body composition in lean women with polycystic ovary syndrome: effect of ethinyl estradiol and drospirenone combination. Contraception 2013; 87: 358-362. [DOI:10.1016/j.contraception.2012.07.005]
29. Zabulienė L, Urboniene J, Tutkuvienė J. Body composition of lean women with polycystic ovary syndrome. Anthropol Rev 2013; 76: 183-198. [DOI:10.2478/anre-2013-0018]
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