International Journal of
Reproductive Biomedicine
Wed, Apr 2, 2025
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Volume 19, Issue 5 (Suppl- 2021)
IJRM 2021, 19(5): 215-215 |
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Hosseini Marnani E, Ghadiri-Anari A, Ramezani-Jolfaie N, Mohammadi M, Abdollahi N, Namayandeh SM, et al . P-48 Effect of fennel supplementation along with high-protein, low-carbohydrate weight-loss diet on insulin resistance and percentage of fat and muscle mass in overweight/obese women with polycystic ovary syndrome. IJRM 2021; 19 (5) :215-215
URL: http://ijrm.ir/article-1-2935-en.html
URL: http://ijrm.ir/article-1-2935-en.html
Hosseini Marnani E * 
1, Ghadiri-Anari A2 , Ramezani-Jolfaie N3 , Mohammadi M3 , Abdollahi N3 , Namayandeh SM4 , Mozaffari-Khosravi H5 , Salehi-Abargouei A3 , Nadjarzadeh A6
1, Ghadiri-Anari A2 , Ramezani-Jolfaie N3 , Mohammadi M3 , Abdollahi N3 , Namayandeh SM4 , Mozaffari-Khosravi H5 , Salehi-Abargouei A3 , Nadjarzadeh A6
1- Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , elham_hosseini1993@yahoo.com
2- Department of Internal Medicine, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4- Research Center of Prevention and Epidemiology of Non-Communicable Diseases, Shahid Sadoghi University of Medical Sciences, Yazd, Iran
5- Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
6- Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Department of Internal Medicine, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4- Research Center of Prevention and Epidemiology of Non-Communicable Diseases, Shahid Sadoghi University of Medical Sciences, Yazd, Iran
5- Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
6- Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (261 Views)
Background: Polycystic ovary syndrome (PCOS) is a common reproductive disorder with prevalence of 5-10% in premenopausal women, which is identified with hyperandrogenism and ovarian dysfunction.
Objective: The aim of this study was to investigate the effects of fennel supplementation with energy-restricted diets on body fat and muscle percentage and insulin resistance in women with PCOS.
Materials and Methods: Sixty-four overweight/obese women with PCOS were randomly allocated to 4 groups for 12 wk as follows: (1) standard diet + fennel (SDF), (2) high-protein, low-carbohydrate diet supplemented with fennel (HPF), (3) standard diet + placebo (SDP), and (4) high-protein, low-carbohydrate diet + placebo (HPP).
Results: After 12 wk of intervention, there were significant changes in the percentage of body fat and muscle in all groups. Decreasing in fasting insulin was −4.12 micIU/ml (p = 0.01) for HPF and −4.5 micIU/ml (p = 0.03) for SDP groups. In addition, HOMA-IR significantly decreased in HPF (p = 0.02) and SDP (p = 0.02) groups.
Conclusion: Energy-restricted diets independent of dietary composition improved the body fat and muscle percentage and insulin resistance indices in women with PCOS. High-protein diet and fennel compared with standard diet and placebo had no significant effect on insulin resistance, body fat and muscle.
Objective: The aim of this study was to investigate the effects of fennel supplementation with energy-restricted diets on body fat and muscle percentage and insulin resistance in women with PCOS.
Materials and Methods: Sixty-four overweight/obese women with PCOS were randomly allocated to 4 groups for 12 wk as follows: (1) standard diet + fennel (SDF), (2) high-protein, low-carbohydrate diet supplemented with fennel (HPF), (3) standard diet + placebo (SDP), and (4) high-protein, low-carbohydrate diet + placebo (HPP).
Results: After 12 wk of intervention, there were significant changes in the percentage of body fat and muscle in all groups. Decreasing in fasting insulin was −4.12 micIU/ml (p = 0.01) for HPF and −4.5 micIU/ml (p = 0.03) for SDP groups. In addition, HOMA-IR significantly decreased in HPF (p = 0.02) and SDP (p = 0.02) groups.
Conclusion: Energy-restricted diets independent of dietary composition improved the body fat and muscle percentage and insulin resistance indices in women with PCOS. High-protein diet and fennel compared with standard diet and placebo had no significant effect on insulin resistance, body fat and muscle.
Type of Study: Congress Abstract |
Subject:
Reproductive Pattology
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