Volume 19, Issue 9 (September 2021)                   IJRM 2021, 19(9): 821-826 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jamal A, Marsoosi V, Sarvestani F, Hashemi N. The correlation between the cerebroplacental ratio and fetal arterial blood gas in appropriate-for-gestational-age fetuses: A cross-sectional study. IJRM 2021; 19 (9) :821-826
URL: http://ijrm.ir/article-1-1306-en.html
1- Department of Perinatology, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Perinatology, Endometriosis Research Center, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. , hashemi.n@iums.ac.ir
Abstract:   (3211 Views)

Background: The cerebroplacental ratio (CPR) is an important index for predicting adverse pregnancy outcomes in small-for-gestational-age and appropriate-for-gestational-age fetuses.
Objective: To find out whether there is an association between the CPR level and the blood cord gases analysis in appropriate for gestational age fetuses.
Material and Method: This cross- sectional study included 347 pregnant women at the gestational age of 37-40 week. Patients had an appropriate-for-gestational-age fetus confirmed from their first ultrasonography results. Participants were divided into two groups based on their CPR, measured before delivery. Finally, after delivery, arterial blood gas level and the incidence of emergency cesarean section, intrapartum fetal distress and neonatal intensive care unit admissions were compared between the two groups.
Results: Fifty-four (15.6%) cases had a CPR below the detection limit of the assay. The incidence of fetal distress, emergency cesarean section, neonatal hospitalization in the neonatal intensive care unit, and pH < 7.2 were significantly lower in women with CPR ≥ 0.67 multiples than in women with a CPR < 0.67 multiples of the median.
Conclusion: The third-trimester CPR is an independent predictor of stillbirth and perinatal mortality and morbidity. The role of UA/MCA Doppler and the CPR in assessing the risk of adverse pregnancy outcomes should be evaluated prospectively.

Full-Text [PDF 262 kb]   (776 Downloads) |   |   Full-Text (HTML)  (318 Views)  
Type of Study: Original Article | Subject: Perinatology

References
1. 1. DeVore GR. The importance of the cerebroplacental ratio in the evaluation of fetal well-being in SGA and AGA fetuses. Am J Obstet Gynecol 2015; 213: 5-15.
2. 2. Flood K, Unterscheider J, Daly S, Geary MP, Kennelly MM, McAuliffe FM, et al. The role of brain sparing in the prediction of adverse outcomes in intrauterine growth restriction: Results of the multicenter PORTO study. Am J Obstet Gynecol 2014; 211: 288. e1-e5.
3. 3. Khalil AA, Morales-Rosello J, Morlando M, Hannan H, Bhide A, Papageorghiou A, et al. Is fetal cerebroplacental ratio an independent predictor of intrapartum fetal compromise and neonatal unit admission? Am J Obstet Gynecol 2015; 213: 54. e1-e10.
4. 4. Akolekar R, Syngelaki A, Gallo DM, Poon LC, Nicolaides KH. Umbilical and fetal middle cerebral artery Doppler at 35-37 weeks' gestation in the prediction of adverse perinatal outcome. Ultrasound Obstet Gynecol 2015; 46: 82-92.
5. 5. Ropacka-Lesiak M, Korbelak T, Świder-Musielak J, Breborowicz G. Cerebroplacental ratio in prediction of adverse perinatal outcome and fetal heart rate disturbances in uncomplicated pregnancy at 40 weeks and beyond. Arch Med Sci 2015; 11: 142.
6. 6. Karlsen HO, Ebbing C, Rasmussen S, Kiserud T, Johnsen SL. Use of conditional centiles of middle cerebral artery pulsatility index and cerebroplacental ratio in the prediction of adverse perinatal outcomes. Acta Obstet Gynecol Scand 2016; 95: 690-696.
7. 7. Morales‐Roselló J, Khalil A, Morlando M, Bhide A, Papageorghiou A, Thilaganathan B. Poor neonatal acid-base status in term fetuses with low cerebroplacental ratio. Ultrasound Obstet Gynecol 2015; 45: 156-161.
8. 8. Nicolaides K, Economides D, Soothill P. Blood gases, pH, and lactate in appropriate-and small-for-gestational-age fetuses. Am J Obstet Gynecol 1989; 161: 996-1001.
9. 9. Morales‐Roselló J, Khalil A, Morlando M, Papageorghiou A, Bhide A, Thilaganathan B. Changes in fetal Doppler indices as a marker of failure to reach growth potential at term. Ultrasound Obstet Gynecol 2014; 43: 303-310.
10. 10. D'antonio F, Patel D, Chandrasekharan N, Thilaganathan B, Bhide A. Role of cerebroplacental ratio for fetal assessment in prolonged pregnancy. Ultrasound Obstet Gynecol 2013; 42: 196-200.
11. 11. Monteith C, Flood K, Mullers S, Unterscheider J, Breathnach F, Daly S, et al. Evaluation of normalization of cerebro-placental ratio as a potential predictor for adverse outcome in SGA fetuses. Am J Obstet Gynecol 2017; 216: 285. e1-e6.
12. 12. Flatley C, Greer R, Kumar S. Magnitude of change in fetal cerebroplacental ratio in third trimester and risk of adverse pregnancy outcome. Ultrasound Obstet Gynecol 2017; 50: 514-519.
13. 13. Morales-Roselló J, Khalil A, Alberola-Rubio J, Hervas-Marín D, Morlando M, Bhide A, et al. Neonatal acid-base status in term fetuses: mathematical models investigating cerebroplacental ratio and birth weight. Fetal Diagnos Ther 2015; 38: 55-60.
14. 14. Regan J, Masters H, Warshak CR. Estimation of the growth rate in fetuses with an abnormal cerebroplacental ratio compared to those with suspected growth restriction without evidence of centralization of blood flow. J Ultrasound Med 2015; 34: 837-842.
15. 15. Khalil A, Morales‐Roselló J, Townsend R, Morlando M, Papageorghiou A, Bhide A, et al. Value of third‐trimester cerebroplacental ratio and uterine artery Doppler indices as predictors of stillbirth and perinatal loss. Ultrasound Obstet Gynecol 2016; 47: 74-80.
16. 16. Murata S, Nakata M, Sumie M, Sugino N. The Doppler cerebroplacental ratio predicts risk of non‐reassuring fetal status for fetal growth restriction in term pregnancy. Ultrasound Obstet Gynecol 2009; 34: 56.
17. 17. Prior T, Paramasivam G, Bennett P, Kumar S. Are fetuses that fail to achieve their growth potential at increased risk of intrapartum compromise? Ultrasound Obstet Gynecol 2015; 46: 460-464.
18. 18. Khalil A, Morales-Rosello J, Khan N, Nath M, Agarwal P, Bhide A, et al. Is cerebroplacental ratio a marker of impaired fetal growth velocity and adverse pregnancy outcome? Am J Obstet Gynecol 2017; 216: 606. e1-10.

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb