دوره 17، شماره 3 - ( 2-1398 )                   جلد 17 شماره 3 صفحات 222-217 | برگشت به فهرست نسخه ها


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Feng C, Lv P, Jin M, Shen J, Huang T. Requirements for confirmation of PCR-RFLP results of polymorphisms. IJRM 2019; 17 (3) :217-222
URL: http://ijrm.ir/article-1-1466-fa.html
Requirements for confirmation of PCR-RFLP results of polymorphisms. International Journal of Reproductive BioMedicine. 1398; 17 (3) :217-222

URL: http://ijrm.ir/article-1-1466-fa.html


چکیده:   (1916 مشاهده)
As clinical investigators and researchers exploring the role of insulin receptor gene (INSR) in polycystic ovary syndrome (PCOS), we wish to express our  concern about the study by Tehrani et al. (1) that aimed to explore the correlation between INSR and adiponectin genes and PCOS. We are afraid that it might have technical flaws and take confusion and concerns to the readership.
نوع مطالعه: Letter to Editor |

فهرست منابع
1. [1] Ramezani Tehrani F, Daneshpour M, Hashemi S, Zarkesh M, Azizi F. Relationship between polymorphism of insulin receptor gene, and adiponectin gene with PCOS. Iran J Reprod Med 2013; 11: 185-194.
2. [2] Ranjzad F, Mahmoudi T, Irani Shemirani A, Mahban A, Nikzamir A, Vahedi M, et al. A common variant in the adiponectin gene and polycystic ovary syndrome risk. Mol Biol Rep 2012; 39: 2313-2319. [DOI:10.1007/s11033-011-0981-1]
3. [3] Murillo R, Munoz D, Williams T, Mugeta N, Caballero P. Application of the PCR-RFLP method for the rapid differentiation of Spodoptera exigua nucleopolyhedrovirus genotypes. J Virol Methods 2006; 135: 1-8. [DOI:10.1016/j.jviromet.2006.01.011]
4. [4] Chen ZJ, Shi YH, Zhao YR, Li Y, Tang R, Zhao LX, et al. [Correlation between single nucleotide polymorphism of insulin receptor gene with polycystic ovary syndrome]. Zhonghua Fu Chan Ke Za Zhi 2004; 39: 582-585.
5. [5] Conway GS, Avey C, Rumsby G. The tyrosine kinase domain of the insulin receptor gene is normal in women with hyperinsulinaemia and polycystic ovary syndrome. Hum Reprod 1994; 9: 1681-1683. [DOI:10.1093/oxfordjournals.humrep.a138773]
6. [6] Lee EJ, Yoo KJ, Kim SJ, Lee SH, Cha KY, Baek KH. Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertil Steril 2006; 86: 380-384. [DOI:10.1016/j.fertnstert.2005.12.073]
7. [7] Kashima K, Yahata T, Fujita K, Tanaka K. Polycystic ovary syndrome: association of a C/T single nucleotide polymorphism at tyrosine kinase domain of insulin receptor gene with pathogenesis among lean Japanese women. J Reprod Med 2013; 58: 491-496.
8. [8] Talbot JA, Bicknell EJ, Rajkhowa M, Krook A, O'Rahilly S, Clayton RN. Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome. J Clin Endocrinol Metab 1996; 81: 1979-1983. [DOI:10.1210/jcem.81.5.8626868]
9. [9] Mukherjee S, Shaikh N, Khavale S, Shinde G, Meherji P, Shah N, et al. Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome. Eur J Endocrinol 2009; 160: 855-862. [DOI:10.1530/EJE-08-0932]
10. [10] Skrgatic L, Baldani DP, Gersak K, Cerne JZ, Ferk P, Coric M. Genetic polymorphisms of INS, INSR and IRS-1 genes are not associated with polycystic ovary syndrome in Croatian women. Coll Antropol 2013; 37: 141-146.
11. [11] Ramos Cirilo PD, Rosa FE, Moreira Ferraz MF, Rainho CA, Pontes A, Rogatto SR. Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome. Gynecol Endocrinol 2012; 28: 190-194. [DOI:10.3109/09513590.2011.593661]
12. [12] Lee EJ, Oh B, Lee JY, Kimm K, Lee SH, Baek KH. A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil Steril 2008; 89: 1213-1220. [DOI:10.1016/j.fertnstert.2007.05.026]
13. [13] Siegel S, Futterweit W, Davies TF, Concepcion ES, Greenberg DA, Villanueva R, et al. A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome. Fertil Steril 2002; 78: 1240-1243. [DOI:10.1016/S0015-0282(02)04241-3]

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