Volume 20, Issue 6 (June 2022)                   Int J Reprod BioMed. 2022, 20(6): 447-460 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Pourmasumi S, Sabeti P, Ghasemi N. Male factor testing in recurrent pregnancy loss cases: A narrative review. Int J Reprod BioMed. 2022; 20 (6) :447-460
URL: http://ijrm.ir/article-1-1525-en.html
Male factor testing in recurrent pregnancy loss cases: A narrative review
Soheila Pourmasumi1 , Parvin Sabeti2 , Nasrin Ghasemi *3
1- Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Clinical Research Development Unit (CRDU), Moradi Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran., Abortion Research Center, Yazd Reproductive Sciences Institute, Bouali Ave., Safaeyeh, Yazd, Iran. Postal Code: 8916877391
2- Department of Anatomy, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran., Abortion Research Center, Yazd Reproductive Sciences Institute, Bouali Ave., Safaeyeh, Yazd, Iran. Postal Code: 8916877391
3- Abortion Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , nghasemi479@gmail.com
Abstract:   (3190 Views)
Recurrent pregnancy loss is a distinct disorder defined as the loss of at least 2 pregnancies before the 20th wk of gestation. With one half of the genome of the embryo belonging to the father, the integrity of the sperm genome is crucial for a successful pregnancy. Semen analysis is recommended for men in such cases to evaluate sperm concentration, morphology, vitality and motility. However, other important sperm parameters such as sperm epigenetics, aneuploidy, Y chromosome microdeletion and chromatin integrity also correlate with successful pregnancy and delivery rate. This article examines the use of different sperm tests and their importance in male partners of women suffering from recurrent pregnancy loss.
Keywords: DNA fragmentation, Sperm, Y chromosome, Recurrent pregnancy loss.
Full-Text [PDF 301 kb]   (1914 Downloads) |   |   Full-Text (HTML)  (826 Views)  
Type of Study: Review Article | Subject: Fertility & Infertility
* Corresponding Author Address: Abortion Research Center, Yazd Reproductive Sciences Institute, Bouali Ave., Safaeyeh, Yazd, Iran. Postal Code: 8916877391
Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb