Volume 19, Issue 12 (December 2021)
IJRM 2021, 19(12): 1085-1090 |
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Elahe Dehghan1 
, Nasim Namiranian2 , Akram Ghadiri-Anari2 , Sied Kazem Razavi Ratki1 , Reyhaneh Azizi * 3
, Nasim Namiranian2 , Akram Ghadiri-Anari2 , Sied Kazem Razavi Ratki1 , Reyhaneh Azizi * 3
1- Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , raihane.azizi@yahoo.com
2- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , raihane.azizi@yahoo.com
Abstract: (1499 Views)
Background: Hyperprolactinemia is one of the most common causes of infertility in women. The prevalence of pituitary tumors is 25-30% among infertile participants with hyperprolactinemia.
Objective: The aim of this study was to describe the causes of hyperprolactinemia in infertile women referred to Yazd Infertility Center.
Materials and Methods: This cross-sectional study was conducted with 182 infertile women with hyperprolactinemia who were referred to Yazd Infertility Center from February 2018 to October 2019. Serum prolactin was assessed by the human prolactin ELISA kit according to the Padtan Gostar Isar protocol. The age, duration of infertility, causes of hyperprolactinemia, and type of infertility treatment were noted. The MRI findings were added.
Results: The mean age of participants was 28.9 ± 0.36 yr and the prolactin level was 76 ± 8.97 ng/ml. The etiology of hyperprolactinemia among the study participants was 35 participants (19.2%) with pituitary adenoma, 47 participants (25.8%) with polycystic ovary syndrome, 14 participants (7.7%) with pituitary adenoma and polycystic ovary syndrome, and 86 participants (47.3%) with idiopathic hyperprolactinemia. The results of this study showed that there was no statistically significant difference between the mean prolactin levels in participants with different causes of hyperprolactinemia (p = 0.31).
Conclusion: Idiopathic hyperprolactinemia and polycystic ovary syndrome are the most common reasons for hyperprolactinemia.
Objective: The aim of this study was to describe the causes of hyperprolactinemia in infertile women referred to Yazd Infertility Center.
Materials and Methods: This cross-sectional study was conducted with 182 infertile women with hyperprolactinemia who were referred to Yazd Infertility Center from February 2018 to October 2019. Serum prolactin was assessed by the human prolactin ELISA kit according to the Padtan Gostar Isar protocol. The age, duration of infertility, causes of hyperprolactinemia, and type of infertility treatment were noted. The MRI findings were added.
Results: The mean age of participants was 28.9 ± 0.36 yr and the prolactin level was 76 ± 8.97 ng/ml. The etiology of hyperprolactinemia among the study participants was 35 participants (19.2%) with pituitary adenoma, 47 participants (25.8%) with polycystic ovary syndrome, 14 participants (7.7%) with pituitary adenoma and polycystic ovary syndrome, and 86 participants (47.3%) with idiopathic hyperprolactinemia. The results of this study showed that there was no statistically significant difference between the mean prolactin levels in participants with different causes of hyperprolactinemia (p = 0.31).
Conclusion: Idiopathic hyperprolactinemia and polycystic ovary syndrome are the most common reasons for hyperprolactinemia.
Type of Study: Original Article |
Subject:
Reproductive Endocrinology
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