Volume 21, Issue 7 (July 2023)                   IJRM 2023, 21(7): 585-590 | Back to browse issues page


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Sadeghi L, Ghasemzadeh A, Hamdi K, Navali N, Hakimi P, Farzadi L. A treatment approach of severe vulvar edema in ovarian hyperstimulation syndrome patient: A case report. IJRM 2023; 21 (7) :585-590
URL: http://ijrm.ir/article-1-2594-en.html
1- Department of Obstetrics and Gynecology, Alzahra Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. , l.farzadi@yahoo.com
2- Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:   (511 Views)
Background: Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication of infertility treatment. Vulvar edema is a disease with various causes and frequent phenomena seen in physiological and pathologic conditions like pregnancy, inflammatory disorders, tumors, idiopathic reasons, and most importantly, in the severe form of OHSS. 
Case Presentation: Here, we report a 26-yr-old woman with severe OHSS, recombinant follicle-stimulating hormone therapy. 8 days later, we observed a mild and asymmetrical swelling of the vulva with severe edema in the right labia. Due to the worsening of the vulvar edema even after 15 days of conservative treatment, hand massage and compressive bandaging of the vulva were performed, which caused rapid recovery within 20 min of the case.
Conclusion: Treatment with a hand massage with lubricant gel followed by compressive bandaging resolved the vulvar edema immediately; it is an easy procedure without any adverse events.

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Type of Study: Case Report | Subject: Reproductive Pattology

References
1. Pinto de Silva MP, Bassani MA, Miquelutti MA, Andrade Marques Ad, do Amaral MTP, de Oliveira MMF, et al. Manual lymphatic drainage and multilayer compression therapy for vulvar edema: A case series. Physiother Theory Pract 2015; 31: 527-531. [DOI:10.3109/09593985.2015.1038375] [PMID]
2. Hadzavdic SL, Jovic A, Hadzavdic A, Grgec DL. Vulvar oedema. Contact Dermatitis 2018; 78: 226-227. [DOI:10.1111/cod.12905] [PMID]
3. Trayes KP, Studdiford JS, Pickle S, Tully AS. Edema: Diagnosis and management. Am Fam Physician 2013; 88: 102-110. [DOI:10.1097/ACM.0b013e318277d5b2] [PMID]
4. Kiyama M, Kanayama K, Roh S, Hattori Y, Oba J, Iida T, et al. Multiple symmetric lipomatosis with vulvar involvement: A rare case report associated with walking difficulty and urination disorder. Eur J Plast Surg 2020; 43: 347-352. [DOI:10.1007/s00238-019-01573-3]
5. Nelson SM. Prevention and management of ovarian hyperstimulation syndrome. Thromb Res 2017; 151 (Suppl.): S61-S64. [DOI:10.1016/S0049-3848(17)30070-1] [PMID]
6. Ma XW, Yin JW, Yang R, Yang S, Li J, Wang Y, et al. [Clinical characteristics of severe late-onset ovarian hyperstimulation syndrome and its impact on the live birth outcome of IVF-ET]. Zhonghua Fu Chan Ke Za Zhi 2022; 57: 678-685. (in Chinese)
7. Leitao VMS, Moroni RM, Seko LMD, Nastri CO, Martins WP. Cabergoline for the prevention of ovarian hyperstimulation syndrome: Systematic review and meta-analysis of randomized controlled trials. Fertil Steril 2014; 101: 664-675. [DOI:10.1016/j.fertnstert.2013.11.005] [PMID]
8. Kovač V, Reljič M, Bizjak T. Causes of massive vulvar edema in patients with severe ovarian hyperstimulation syndrome: A case report and literature review. Am J Case Rep 2019; 20: 238-241. [DOI:10.12659/AJCR.913149] [PMID] [PMCID]
9. Coccia ME, Bracco GL, Cattaneo A, Scarselli G. Massive vulvar edema in ovarian hyperstimulation syndrome. A case report. J Reprod Med 1995; 40: 659-660.
10. Sopa N, Toftager M. Post laparoscopic massive vulvar edema in woman with ovarian hyperstimulation syndrome. Int J Case Rep Images 2018; 9: 66-68. [DOI:10.5348/ijcri-201802-CL-10140]
11. Kalafat E, Acar D, Aytac R. Swollen labia majora: An unusual presentation of occult inguinal hernia secondary to ovarian hyperstimulation syndrome. Taiwan J Obstet Gynecol 2016; 55: 446-447. [DOI:10.1016/j.tjog.2016.04.026] [PMID]
12. Cline DL. Massive vulvar edema in ovarian hyperstimulation syndrome. J Reprod Med 1996; 41: 780.
13. Hijazi A, Al-Jaroudi D. Myrrh for treatment of severe vulvar edema in ovarian hyperstimulation syndrome. Case Rep Women's Health 2017; 15: 8-10. [DOI:10.1016/j.crwh.2017.06.002] [PMID] [PMCID]
14. Bhairavi S, Rajendran J, Dash S, Dash S. Postparacentesis vulvar edema in ovarian hyper stimulation syndrome. Int J Reprod Contracept Obstet Gynecol 2016; 5: 4064-4067. [DOI:10.18203/2320-1770.ijrcog20163891]
15. Habek D, Habek JČ, Vujic B. Nontraumatic chyloperitoneum in pregnancy. Eur J Obstet Gynecol Reprod Biol 2005; 122: 245-247. [DOI:10.1016/j.ejogrb.2005.01.022] [PMID]
16. Abdul MA, Odogwu K, Madugu N. Gross vulva odema complicating severe pre-eclampsia/eclampsia: A case series. Niger J Med 2011; 20: 380-382.
17. Mulisya O, Mastaki M, Gertrude T, Tasi K, Mathe JK. Spontaneous massive vulvar edema in pregnancy: A case report. Case Rep Obstet Gynecol 2018; 2018: 7651254. [DOI:10.1155/2018/7651254] [PMID] [PMCID]

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