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Reproductive Biomedicine
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Volume 10, Issue 5 (10-2012)
IJRM 2012, 10(5): 473-476 |
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Zadehmodares S, Baheiraei N, Sharafi A, Hedayati M, Mousavi M. The ratio of cervical fluid and serum human chorionic gonadotropin as a predictor of abortion. IJRM 2012; 10 (5) :473-476
URL: http://ijrm.ir/article-1-305-en.html
URL: http://ijrm.ir/article-1-305-en.html
Abstract: (2753 Views)
Background: Progressions in science and technology have generated several methods for delaying preterm delivery and abortion; therefore, discovering an easy, non-invasive, practical, and non-expensive predictive factor can help us to perform preventive methods in healthy pregnant women, without any risk factors.
Objective: To indicate an appropriate index for predicting abortion in early pregnancy.
Materials and Methods: In a prospective study, 73 pregnant women who had a singleton pregnancy, had no complications or history of abortion or disease, and were referred to Mahdieh and Taleghani Hospitals between 2007-2009, were evaluated. Blood and cervical fluid samples were obtained thrice from all patients: at the first visit, after 1 week, and 1-2 weeks later. They were followed up until the 12th week of gestation.
Results: Using the receiver-operator characteristic (ROC) curve analysis, 1.62 was obtained as the cut-off point for the cervical fluid: serum human chorionic gonadotropin concentration ratio; 14 patients (19.2%) experienced abortion, and 12 women (70.6%) had a ratio ≥1.62. Of the pregnant women with a ratio of <1.62, 3.6% had an abortion.
Conclusion: Pregnant women who do not show any signs of abortion and have a high cervical fluid: serum HCG concentration ratio are at risk of abortion; therefore, the cut-off point might be an appropriate index for predicting abortion in early pregnancy.
Objective: To indicate an appropriate index for predicting abortion in early pregnancy.
Materials and Methods: In a prospective study, 73 pregnant women who had a singleton pregnancy, had no complications or history of abortion or disease, and were referred to Mahdieh and Taleghani Hospitals between 2007-2009, were evaluated. Blood and cervical fluid samples were obtained thrice from all patients: at the first visit, after 1 week, and 1-2 weeks later. They were followed up until the 12th week of gestation.
Results: Using the receiver-operator characteristic (ROC) curve analysis, 1.62 was obtained as the cut-off point for the cervical fluid: serum human chorionic gonadotropin concentration ratio; 14 patients (19.2%) experienced abortion, and 12 women (70.6%) had a ratio ≥1.62. Of the pregnant women with a ratio of <1.62, 3.6% had an abortion.
Conclusion: Pregnant women who do not show any signs of abortion and have a high cervical fluid: serum HCG concentration ratio are at risk of abortion; therefore, the cut-off point might be an appropriate index for predicting abortion in early pregnancy.
Keywords: Abortion, Cervical human chorionic gonadotropin, Cervical fluid, Prediction of abortion, Serum human chorionic gonadotropin
Type of Study: Original Article |
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