یکشنبه 15 شهریور 1405
[Archive]
دوره 24، شماره 7 - ( 4-1405 )
جلد 24 شماره 7 صفحات 604-585 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Hojati V. The role of gene polymorphisms in infertility, polyendocrine metabolic ovarian syndrome and recurrent miscarriage in the Iranian women population: A review study. IJRM 2026; 24 (7) :585-604
URL: http://ijrm.ir/article-1-3800-fa.html
URL: http://ijrm.ir/article-1-3800-fa.html
نقش پلیمورفیسمهای ژنی در ناباروری، سندرم تخمدان متابولیک پلی اندوکرین و سقط مکرر در جمعیت زنان ایرانی: یک مطالعه مروری. International Journal of Reproductive BioMedicine. 1405; 24 (7) :585-604
چکیده: (19 مشاهده)
بیش از 40% از علل ناباروری به زنان نسبت داده میشود. سندرم تخمدان متابولیک پلیاندوکرین (PMOS) یکی از علل مهم و شایع ناباروری در زنان است. سقط مکرر با وقوع 2 یا 3 سقط خودبهخودی متوالی قبل از هفته بیستم بارداری تعریف میشود. منشأ سقط مکرر در 50% موارد ناشناخته است که به آن سقط مکرر ایدیوپاتیک میگویند. هدف از مطالعه حاضر بررسی ارتباط بین پلیمورفیسمهای ژنی و ناباروری، PMOS و سقط مکرر در زنان ایرانی است. این مطالعه مروری با بررسی منابع معتبر داخلی و خارجی بین سالهای 2000 تا 2026 انجام شد. برای این منظور، 80 مقاله با استفاده از پایگاههای اطلاعات علمی شامل Scopus ،ScienceDirect و PubMed با تأکید بر مرتبطترین و جدیدترین منابع انتخاب و بررسی شدند. نتایج مطالعات نشان دهنده ارتباط مؤثر برخی از این پلیمورفیسمهای ژنی با ناباروری، PMOS و سقط مکرر در زنان ایرانی است. برخی از پلیمورفیسمهای ژنی نیز هیچ ارتباطی با بیماریهای ذکر شده نشان ندادند. برای درک بهتر ارتباط این پلیمورفیسمها با ناباروری و سقط مکرر در زنان، نیاز به جمعیتهای بزرگتر با تعداد بیشتر و مطالعه تمام جنبههای محیطی و اقلیمی جمعیتها است. بررسی نقش ژنهای مختلف در پاسخ بدن به داروهای مختلف از اهمیت بالایی در تعیین روشهای درمانی مناسب برخوردار است و همچنین میتواند در غربالگری جمعیتها اهمیت داشته باشد.
نوع مطالعه: Review article |
فهرست منابع
1. Jalali E, Hojati V. [The role of gene polymorphisms in idiopathic infertility of Iranian men]. Journal of Animal Biology 2026; 18: 155-174. (In Persian)
2. Ghodsi M, Hojati V, Attaranzadeh A, Saifi B. A cross-sectional study on the follicular fluid concentration of some interleukins and clinical factors in polycystic ovary syndrome patients. Int J Women's Health Reprod Sci 2021; 9: 124-129. [DOI:10.15296/ijwhr.2021.22]
3. Ghodsi M, Hojati V, Attaranzadeh A, Saifi B. Evaluation of IL-3, IL-5, and IL-6 concentration in the follicular fluid of women with endometriosis: A cross-sectional study. Int J Reprod BioMed 2022; 20: 213-220. [DOI:10.18502/ijrm.v20i3.10713] [PMID] [PMCID]
4. Mohebbi A, Hojati V, Majidi Zolbin M, Aflatoonian R. Histopathologic evaluation of the inflammatory factors and stromal cells in the endometriosis lesions: A case-control study. Int J Reprod BioMed 2022; 20: 819-830. [DOI:10.18502/ijrm.v20i10.12266] [PMID] [PMCID]
5. Elahi M, Hojati1 V, Hashemitabar M, Afrough M, Mohammadpour Kargar H, Dastoorpoor M. Negative effect of varicocele on sperm mitochondrial dysfunction: A cross-sectional study. Int J Reprod BioMed 2023; 21: 323-332. [DOI:10.18502/ijrm.v21i4.13271] [PMID]
6. Heidarian F, Hojati V, Golijanian Moghadam R. [Investigating C23237T polymorphism of Cyp3a4 gene in healthy people of west Mazandaran in terms of age and gender]. J Anim Biol 2023; 15: 81-93. (In Persian)
7. Heydarzadeh H, Hojati V, Ebnerasuly F. [Evaluation of rs2016520 polymorphism in PPARD gene and its association with serum low density lipoprotein (LDL) in Iranian population]. Exp Anim Biol 2024; 12: 29-39. (In Persian)
8. Mohebbi A, Hojati V, Aflatoonian R, Majidi Zolbin M. [Investigation of targeted metabolites and organic acids resulting from cellular metabolism in the culture medium of cells extracted from endometriosis tissue using the GC/MS technique: A metabolomics approach]. New Cell Mol Biotechnol J 2025; 15: 41-60. (In Persian)
9. Imanian E, Hojati V, Ebnerasuly F. [Evaluation of rs1205 polymorphism in C-reactive protein encodind gene and its association with serum low-density lipoprotein in Iranian population]. Iran J Diabet Metab 2025; 25: 472-483. (In Persian)
10. Sari S. [Analysis of androgen receptor gene mutations in female with infertility]. Yafteh 2017; 19: 1-7. (In Persian)
11. Sheikhha MH, Kalantar SM, Aflatoonian A. The relationship between estrogen receptor alpha gene polymorphism and ovarian response to ovulatin induction in woman under IVF treatment. J Reprod Infertil 2007; 7: 315-323.
12. Ashrafi Mahabadi Sh, Tafvizi F. Reduction of soluble leptin receptor levels in women with unexplained infertility and the effect of leptin receptor Gln223Arg polymorphism on its serum level. J Obstet Gynecol Cancer Res 2020; 5: 149-158. [DOI:10.30699/jogcr.5.4.149]
13. Yousefkhah P, Vaziri H, Mirzapour T. [Association of KISS1R gene polymorphism (rs397515615) with idiopathic female infertility in the northern of Iran]. J Ilam Univ Med Sci 2024; 32: 99-109. (In Persian)
14. Pashaiefar H, Sheikhha MH, Kalantar SM, Jahaninejad T, Zaimy MA, Ghasemi N. Analysis of MLH3 C2531T polymorphism in Iranian women with unexplained infertility. Iran J Reprod Med 2013; 11: 19-24.
15. Sadat Eshaghi F, Dehghan Tezerjani M, Ghasemi N, Dehghani M. Association study of ESR1 rs9340799, rs2234693, and MMP2 rs243865 variants in Iranian women with premature ovarian insufficiency: A case-control study. Int J Reprod BioMed 2022; 20: 841-850. [DOI:10.18502/ijrm.v20i10.12268] [PMID] [PMCID]
16. Borjian Boroujeni P, Zamanian MR, Roodgar Saffari J, Mohseni Meybodi A. The association between thrombophilic genes alterations and poor ovarian response in infertile women: A retrospective case-control study. J Obstet Gynaecol 2022; 42: 127-132. [DOI:10.1080/01443615.2021.1871885] [PMID]
17. Borjian Boroujeni PB, Rooney K, Alikhani M, Rahmati S, Feli G, Haratian K, et al. Evaluation of TUBB8 gene alterations in infertile women with oocyte maturation and cleavage arrest referred to Royan Institute. Reprod Biomed Online 2023; 47: 103226. [DOI:10.1016/j.rbmo.2023.04.017] [PMID]
18. Sahmani M, Nouri M, Sakhinia E, Sirati-Sabet M, Farzadi L, Najafipour R. [The effect of His447His polymorphism of PPARγ gene on oocytes and fertility in ectopic fertilization]. J Qazvin Univ Med Sci 2010; 14: 5-11. (In Persian)
19. Sonbolestan ES, Sazegar H, Zia-Jahromi N, Mohamadi Farsani F. [Investigating the relationship between C677T polymorphism of the methylenetetrahydrofolate reductase gene and the levels of homocysteine in primary and secondary infertile women in Isfahan]. J Fasa Univ Med Sci 2018; 8: 647-656. (In Persian)
20. Zarrin P, Tabatabaei SN, Moshtaghion SM, Falahati A, Ghasemi N. [Study of polymorphisms of exon 2 of BMP15 gene and exon 9 of BMPR1B gene in Iranian infertile women with premature ovarian failure]. J Mashhad Univ Med Sci 2014; 65: 1714-1729. (In Persian)
21. Siahpoosh Z, Vaziri H, Roohi H. [Studying the association of rs587777844 KISS1R gene polymorphism with infertility in a woman population from Guilan province]. Pars J Med Sci 2022; 15: 16-22. (In Persian) [DOI:10.29252/jmj.15.1.16]
22. Davoodi M, Naeimi S, Moghanibashi MM. [Investigation of IL-17Agene polymorphism (Rs2275913) with infertility in southern Iranian women]. J Shahid Sadughi Univ Med Sci 2020; 28: 2574-2583. (In Persian)
23. Sepahi Hossein Abadi N, Kohan L, Rasekh Jahromi A. [Evaluation of mir-126 rs4636297 gene polymorphism in infertile women with endometriosis]. J Mazandaran Univ Med Sci 2016; 26: 1-7. (In Persian)
24. Motovali-Bashi M, Sedaghat S, Dehghanian F. Association between serum paraoxonase 1 activities (PONase/AREase) and L55M polymorphism in risk of female infertility. Avicenna J Med Biotechnol 2015; 7: 173-178.
25. Sari S, Sari G. [Association of estrogen receptor-β Gene polymorphism with infertility in Iranian women]. J Mashhad Univ Med Sci 2016; 59: 210-214. (In Persian)
26. Haghighi H, Vaziri HR, Zahiri Z. [Analysis of association of FSHR 1255G>A polymorphism with infertility in women]. J Guilan Univ Med Sci 2016; 25: 26-33. (In Persian)
27. Jodeiry S, Vaziri HR, Zahiri Z. [Analysis of ESR1 rs104893956 polymorphism with infertility in Guilanian women]. J Arak Uni Med Sci 2016; 18: 19-26. (In Persian)
28. Mykhalchenko K, Lizneva D, Trofimova T, Walker W, Suturina L, Diamond MP, et al. Genetics of polycystic ovary syndrome. Exp Rev Mol Diagn 2017; 17: 723-733. [DOI:10.1080/14737159.2017.1340833] [PMID]
29. Chen Y, Fang SY. Potential genetic polymorphisms predicting polycystic ovary syndrome. Endocr Connect 2018; 7: R187-R195. [DOI:10.1530/EC-18-0121] [PMID] [PMCID]
30. Ghalehzan MB, Afrasiabi A, Daneshmand F, Ali-Hassanzadeh M, Gharesi-Fard B, Majidi Z. Polymorphism of the insulin resistin (RETN) gene in susceptibility to polycystic ovary syndrome (PCOS) in an Iranian population. BMC Womens Health 2025; 25: 63. [DOI:10.1186/s12905-025-03553-1] [PMID] [PMCID]
31. Sadr Tabatabaie SF, Salahshoorifar I, Pouresmaeili F, Hosseinpour Golloo Z, Aarabi A, Kholghi Oskooei V, et al. Association between IL-6 -174 G/C (rs1800795) and IL-1A -889 C/T (rs1800587) cytokine variants with polycystic ovary syndrome in Iranian women: A case-control study. Gene 2025; 933: 148906. [DOI:10.1016/j.gene.2024.148906] [PMID]
32. Heidarpanah S, Kohan L, Hashemi SS. [Relationship between Fas rs1800682 gene polymorphism and susceptibility to polycystic ovary syndrome]. J Arak Univ Med Sci 2017; 19: 9-16. (In Persian)
33. Rezaei Z, Kohan L, Yavarian M. [Role of SIRT-1 rs7895833 polymorphism in susceptibility to polycystic ovary syndrome]. J Shahid Sadoughi Univ Med Sci 2017; 24: 861-867. (In Persian)
34. Mehdizadeh A, Kalantar SM, Sheikhha MH, Aali BS, Ghanei A. Association of SNP rs.2414096 CYP19 gene with polycystic ovarian syndrome in Iranian women. Int J Reprod BioMed 2017; 15: 491-496. [DOI:10.29252/ijrm.15.8.491] [PMID] [PMCID]
35. Kordestani F, Mazloomi S, Mortazavi Y, Mazloomzadeh S, Fathi M, Rahmanpour H, et al. Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome. BMC Med Genet 2018; 19: 149. [DOI:10.1186/s12881-018-0662-1] [PMID] [PMCID]
36. Zafari Zangeneh F, Masoumi M, Seyed Aboutorabi E. [Investigation of adrenoceptor genes (β2 & β3) in women with polycystic ovary syndrome]. Tehran Univ Med J 2018; 76: 588-594. (In Persian)
37. Hesampour F, Namavar Jahromi B, Tahmasebi F, Gharesi-Fard B. Association between interleukin-32 and interleukin-17A single nucleotide polymorphisms and serum levels with polycystic ovary syndrome. Iran J Allergy Asthma Immunol 2019; 18: 91-99. [DOI:10.18502/ijaai.v18i1.634] [PMID]
38. Ghasemi M, Heidari Nia M, Hashemi M, Keikha N, Fazeli K, Taji O, et al. An association study of polymorphisms in the H19 imprinted gene in an Iranian population with the risk of polycystic ovary syndrome. Biol Reprod 2020; 103: 978-985. [DOI:10.1093/biolre/ioaa131] [PMID]
39. Miraghaee SS, Sohrabi M, Jalili C, Bahrehmand F. Assessment of GSTO1 (A140D) and GSTO2 (N142D) gene polymorphisms in Iranian women with polycystic ovarian syndrome. Rep Biochem Mol Biol 2020; 9: 8-13. [DOI:10.29252/rbmb.9.1.8] [PMID] [PMCID]
40. Kargasheh FB, Ansaripour S, Borumandnia N, Moradi N, Zandieh Z, Maleki M, et al. Association of leptin G2548A and leptin receptor Q223R polymorphisms and their serum levels with infertility and recurrent pregnancy loss in Iranian women with polycystic ovary syndrome. PLoS One 2021; 16: e0255920. [DOI:10.1371/journal.pone.0255920] [PMID] [PMCID]
41. Seyed Abutorabi E, Hossein Rashidi B, Irani S, Haghollahi F, Bagheri M. Investigation of the FSHR, CYP11, and INSR mutations and polymorphisms in Iranian infertile women with polycystic ovary syndrome (PCOS). Rep Biochem Mol Biol 2021; 9: 470-477. [DOI:10.52547/rbmb.9.4.470] [PMID] [PMCID]
42. Naserpoor L, Jannatifar R, Roshanaei K, Khoshandam M, Kallhor N. Association of rs13429458 and rs12478601 single nucleotide polymorphisms of THADA gene with polycystic ovary syndrome. Int J Fertil Steril 2022; 16: 36-41.
43. Biglari-Zadeh Gh, Sargazi S, Mohammadi M, Ghasemi M, Majidpour M, Saravani R, et al. Relationship between genetic polymorphisms in cell cycle regulatory gene TP53 and polycystic ovarian syndrome: A case-control study and in silico analyses. Biochem Genet 2023; 61: 1827-1849. [DOI:10.1007/s10528-023-10349-1] [PMID]
44. Rakhshani Nejad A, Sargazi S, Ghasemi M, Samareh Moosavi S, Heidari Nia M, Saravani R. Association study to evaluate Foxo1 and Foxo3 gene polymorphisms in polycystic ovary syndrome: A preliminary case-control study and in silico analysis. Mol Biol Rep 2023; 50: 3569-3580. [DOI:10.1007/s11033-023-08292-w] [PMID]
45. Akbari LN, Kheirollahi A, Vatannejad A, Hamidi H. Association of rs4588 polymorphism in vitamin D binding protein gene with polycystic ovarian syndrome in Iranian women: A case-control study. BMC Res Notes 2024; 17: 207. [DOI:10.1186/s13104-024-06857-x] [PMID] [PMCID]
46. Hamidi H, Kheirollahi A, Vatannejad A. The association of rs7041 polymorphism with infertility and recurrent pregnancy loss in Iranian women with polycystic ovary syndrome. BMC Res Notes 2025; 18: 242. [DOI:10.1186/s13104-025-07312-1] [PMID] [PMCID]
47. Fathy P, Cheraghi E, Miresmaeili SM. Association between single nucleotide polymorphisms (rs1484215 and rs6495096) in CYP11A1 Gene in Iranian women with polycystic ovary syndrome. J Reprod Infertil 2023; 24: 18-25. [DOI:10.18502/jri.v24i1.11905] [PMID] [PMCID]
48. Mazrouei B, Heidari MM, Khatami M, Tahmasebi M. [Molecular mechanisms of recurrent pregnancy loss]. J Shahid Sadughi Univ Med Sci 2020; 28: 2255-2271. (in Persian)
49. Khaleghparast A, Morovati S, Noormohammadi Z. [Evaluation of the association between the C677T and A1298C polymorphisms of MTHFR gene and recurrent miscarriage]. Sci J Blood Transfus Org 2011; 8: 88-95. (In Persian)
50. Khaleghparast A, Morovvati S. [Association between the PAI-1 4G/5G promoter polymorphism and recurrent miscarriage]. Blood J 2012; 9: 273-280. (In Persian)
51. Shakarami F, Akbari M, Zare Karizi S, Ajamian F. [Association of angiotensin converting enzyme (ACE), D/I polymorphisms with recurrent pregnancy loss]. Armaghane Danech 2014; 19: 442-449. (In Persian)
52. Naseri Arzanagh F, Morovvati S. [A survey on relationship between progesterone receptor gene polymorphisms and recurrent spontaneous abortions: A short report]. J Rafsanjan Univ Med Sci 2016; 15: 287-292. (In Persian)
53. Khanbarari F, Vakili M, Samadi M. [The relationship between rs2488457 polymorphism of PTPN22 gene and recurrent pregnancy loss (RPL)]. Iran J Obstetr Gynecol Infertil 2017; 20: 49-55. (In Persian)
54. Tohidi N, Ghorbian S. [Investigating the association of RAN (rs 14035) and XPO5 (rs 2257082) genes polymorphisms with the recurrent pregnancy loss in women referred to Imam Khomeini hospital of Ardabil during 2015-2017 years]. J Rafsanjan Univ Med Sci 2018; 17: 201-212. (In Persian)
55. Nemati Vahedi S, Kheirkhah B, Malekirad AA. [Association between polymorphism of has-miR-125 (rs12976445) and susceptibility to idiopathic recurrent pregnancy loss in Iranian women]. Iran J Obstetr Gynecol Infertil 2020; 23: 37-48. (In Persian)
56. Yousefian M, Angaji SA, Siasi E, Rahmani SA, Abbasalizadeh Khiaban S. Association of polymorphisms of F2 (rs3136520) and PAI-1(rs6090) genes with recurrent pregnancy loss in Iranian Azari women. Avicenna J Clin Med 2021; 28: 118-125. [DOI:10.52547/ajcm.28.2.118]
57. Yousefian M, Angaji S, Siasi E, Rahmani S, Abbasalizadeh Khiaban S. [Association of Rs16260 polymorphism of CDH1 gene with recurrent pregnancy loss in Iranian-Azeri women]. Armaghane Danesh 2022; 27: 507-516. (In Persian) [DOI:10.52547/armaghanj.27.4.507]
58. Rezanezhadi M, Joshagani HR. [Relationship between coagulation factors and polymorphism of effective thrombophilic genes with recurrent abortions]. J Gorgan Univ Med Sci 2022; 24: 111-117. (In Persian)
59. Ghaderi Nejad N, Saboori F, Mansour Samaei N, Kordi-Tamandani DM. The relationship between FXIII Val34Leu and PAI-1 4G/5G gene polymorphisms and recurrent miscarriage in women from Golestan province. J Epigenet 2022; 3: 7-12.
60. Fotoohi M, Ghasemi N, Mirghanizadeh SA, Vakili M, Samadi M. Association between HLA-E gene polymorphism and unexplained recurrent spontaneous abortion (RSA) in Iranian women. Int J Reprod BioMed 2016; 14: 477-482. [DOI:10.29252/ijrm.14.7.7] [PMID] [PMCID]
61. Daraei S, Angaji SA, Morovvati S, Tahmaseb M, Asari N. [Association of 1082G/A estrogen receptor genes polymorphisms with recurrent abortions using AS-PCR]. Sci J Kurdistan Univ Med Sci 2015; 20: 93-101. (In Persian)
62. Amin Beidokhti M, Mirfakhraie R, Zare Karizi S, Karamoldin F, Omrani M, Sarsabili N. [To study the association of miR-196a2 rs11614913 polymorphism with the risk of idiopathic recurrent pregnancy loss]. J Arak Uni Med Sci 2015; 18: 11-17. (In Persian)
63. Jabbarour Bonyadi M, Mohammadi A, Khalajkondori M, Taghavi S. [The ADA*2 allele of the adenosine deaminase gene and recurrent spontaneous abortions in Northwest of Iran]. J Ardabil Univ Med Sci 2015; 15: 137-143. (In Persian)
64. Bahrami Hidaji F, Asaadi Tehrani G. [Association between the VEGF (2578C/A) and KDR (Q724H) gene polymorphisms and recurrent spontaneous abortion VEGF and KDR gene polymorphisms and recurrent spontaneous abortion]. Pajoohandeh 2016; 21: 6-12. (In Persian)
65. Amiri Jahromi R, Nasiri M. [Analyzing association of the IRF-5 rs10954213 gene polymorphism with the risk of idiopathic recurrent pregnancy losses in south Iranian women]. J Ilam Univ Med Sci 2018; 26: 94-102. (In Persian) [DOI:10.29252/sjimu.26.1.94]
66. Ameri Z, Mehmannavaz Y. [Relationship of 536C/T Tissue factor pathway inhibitor gene and AluI/D tissue-type plasminogen activator gene polymorphisms with recurrent pregnancy loss in Iranian Azeri women]. Pathobiol Res 2018; 21: 147-152. (In Persian)
67. Mazdapour M, Dehghani Ashkezari M, Seifati M. [Association between HOXA10 (rs267601473) polymorphism and recurrent spontaneous abortion]. J Shahid Sadughi Univ Med Sci 2019; 27: 1254-1261. (In Persian)
68. Mazdapour M, Dehghani Ashkezari M, Seifati SM. Analysis of BMP4 (rs121912765) polymorphism in Iranian women with history of recurrent spontaneous abortion: A case-control study. Biomed Rep 2019; 10: 29-32. [DOI:10.3892/br.2018.1170] [PMID] [PMCID]
69. Hajizadeh S, Choobineh H, Omidkhoda A, Alizadeh S, Sharifi MJ, Kavosh Z. [Study of association between factor XI polymorphism and recurrent miscarriage in Iran Helal Infertility Center (Rouyesh) patients]. Payavard 2019; 13: 223-229. (In Persian)
70. Tabasi S, Hoseini SM. Association of rs4648551 polymorphism in p73 gene in Iranian woman with idiopathic recurrent pregnancy loss. Iran J Obstet Gynecol Infertil 2020; 23: 69-77.
71. Najafi Z, Khalaj Kondori M, Hosseinpour Feizi M, Abbasaliizadeh S. [Association analysis of the HLA-G upstream polymorphism Rs1736933 with the recurrent spontaneous abortion]. J Babol Univ Med Sci 2020; 22: 175-180. (In Persian)
72. Sohrabi A, Eskandari F, Hajia M. [Analysis of polymorphisms of thrombophilia genes as risk factor of miscarriage: A cross-sectional descriptive study]. Iran J Obstet Gynecol Infertil 2020; 23: 39-44. (In Persian)
73. Khasevani L, Khalaj-Kondori M, Ebrahimi B. [Association of rs2249863 and rs1233334 polymorphisms of the upstream region of HLA-G gene with recurrent spontaneous abortion in women from Northwest of Iran during 2018-2019]. Iran J Obstet Gynecol Infertil 2020; 23: 52-60. (In Persian)
74. Ebrahimi Behnam B, Khalaj Kondori M, Hoseinpour Feizi MA. [Association of rs1632943 and rs1736932 polymorphisms of HLA-G gene with recurrent abortion in the women in northwest of Iran]. Sci J Kurdistan Univ Med Sci 2021; 26: 69-82. (in Persian) [DOI:10.52547/sjku.26.6.82]
75. Bagheri R, Rahmani SA, Khoramifar L, Ilkhchoui S. [Study of common chromosomal abnormalities and polymorphisms (4G/5G) of the plasminogen activator inhibitor (PAI-1) gene and mutation (G2021. A) of the prothrombin (F2) gene in women with a history of recurrent miscarriage in the Northwest of the country]. J Tabriz Univ Med Sci 2021; 43: 400-409. (In Persian) [DOI:10.34172/mj.2021.066]
76. Mazrouei B, Heidari MM, Khatami M. [Analysis of missense mutations of CX3CR1 gene in patients with recurrent pregnancy loss using bioinformatics tools]. J Ilam Univ Med Sci 2022; 30: 12-28. (In Persian) [DOI:10.52547/sjimu.30.3.12]
77. Shokrzadeh M, Mohammadpour A, Heidari Z. [The association of beta fibrinogen-455 G/A (rs1800790) gene polymorphism with recurrent abortion in Iranian women]. Pars J Med Sci 2022; 17: 56-62. (In Persian)
78. Hatami R, Moniri Javadhesari S, Mohseni J, Pouladi N. [Association of LncRNAHULC gene rs17144343 G>A polymorphism with susceptibility to recurrent spontaneous miscarriage in women of Eastern Azerbaijan, Iran]. Iran J Obstet Gynecol Infertil 2023; 26: 63-74. (In Persian)
79. Karamzadeh A, Bossaghzadeh F, Hajjari M. Evaluation of polymorphisms associated with recurrent miscarriage in MTHFR gene in Khuzestan province. Cell Mol Res 2024; 37: 289-303.
80. Yousefian M, Angaji A, Siasi E, Rahmani SA, Abbasalizadeh Khiaban S. Role of CYP1A1, CYP2D6, and NOS3 gene polymorphisms in idiopathic recurrent pregnancy loss in the Iranian Azeri population: A case-control study. Int J Reprod BioMed 2022; 20: 671-682. [DOI:10.18502/ijrm.v20i8.11756] [PMID] [PMCID]
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
