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Reproductive Biomedicine
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Volume 12, Issue 4 (5-2014)
IJRM 2014, 12(4): 243-248 |
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Hafizi L, Gholizadeh M, Karimi M, Hosseini G, Mostafavi-Toroghi H, Haddadi M, et al . Effects of magnetized water on ovary, pre-implantation stage endometrial and fallopian tube epithelial cells in mice. IJRM 2014; 12 (4) :243-248
URL: http://ijrm.ir/article-1-531-en.html
URL: http://ijrm.ir/article-1-531-en.html
Leili Hafizi1 
, Mostafa Gholizadeh2 , Mohammad Karimi3 , Golkoo Hosseini * 4, Hesam Mostafavi-Toroghi5 , Mehdi Haddadi6 , Amin Rezaiean3 , Mahmoud Ebrahimi7 , Neda Emami Meibodi8
, Mostafa Gholizadeh2 , Mohammad Karimi3 , Golkoo Hosseini * 4, Hesam Mostafavi-Toroghi5 , Mehdi Haddadi6 , Amin Rezaiean3 , Mahmoud Ebrahimi7 , Neda Emami Meibodi8
1- Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran
2- Department of Chemistry, Faculty of Basic Sciences, Ferdowsi University, Mashhad, Iran
3- Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran ,Golkoo.hoseini@gmail.com
5- Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6- Department of Microbiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
7- Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
8- Department of Biomedical Engineering, Engineering Faculty, Islamic Azad University, Mashhad, Iran
2- Department of Chemistry, Faculty of Basic Sciences, Ferdowsi University, Mashhad, Iran
3- Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran ,
5- Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6- Department of Microbiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
7- Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
8- Department of Biomedical Engineering, Engineering Faculty, Islamic Azad University, Mashhad, Iran
Abstract: (2891 Views)
Background: Magnetized water has made many improvements in industry, agriculture and medicine. However its utilization in medicine still remains controversial.
Objective: In this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice.
Materials and Methods: Eighty female NRMI mice were recruited to this experimental study and randomly divided into two groups: the control group which drank normal water and the experimental (case) group which drank magnetized water for 2 weeks. Super-ovulation was induced in these mice and then they were mated with male mice as well. Samples of ovary, uterus and fallopian tube were obtained at the pre-implantation stage. Then, after preparation, the number of corpus lutea in each ovary was counted and the height of fallopian and endometrial epithelial cells was measured by light microscopy.
Results: Data analysis showed a significant increase in the mean number of corpus lutea and the height of epithelial cells in fallopian tube comparing the case with the control group (p=0.01, p=0.002 respectively) whereas uterus epithelial cells of the case group showed insignificant increase in height, in compare with the control group (p=0.052).
Conclusion: Our results suggest that magnetized water intake increases the number of corpus lutea and the height of fallopian tube epithelial cells. Further research is needed to determine whether this will increase in the success rate of fertility.
Objective: In this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice.
Materials and Methods: Eighty female NRMI mice were recruited to this experimental study and randomly divided into two groups: the control group which drank normal water and the experimental (case) group which drank magnetized water for 2 weeks. Super-ovulation was induced in these mice and then they were mated with male mice as well. Samples of ovary, uterus and fallopian tube were obtained at the pre-implantation stage. Then, after preparation, the number of corpus lutea in each ovary was counted and the height of fallopian and endometrial epithelial cells was measured by light microscopy.
Results: Data analysis showed a significant increase in the mean number of corpus lutea and the height of epithelial cells in fallopian tube comparing the case with the control group (p=0.01, p=0.002 respectively) whereas uterus epithelial cells of the case group showed insignificant increase in height, in compare with the control group (p=0.052).
Conclusion: Our results suggest that magnetized water intake increases the number of corpus lutea and the height of fallopian tube epithelial cells. Further research is needed to determine whether this will increase in the success rate of fertility.
Type of Study: Original Article |
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