Volume 14, Issue 3 (3-2016)                   IJRM 2016, 14(3): 167-172 | Back to browse issues page

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Aflatoonian A, Karimzadeh Maybodi M A, Aflatoonian N, Tabibnejad N, Amir-Arjmand M H, Soleimani M, et al . Perinatal outcome in fresh versus frozen embryo transfer in ART cycles. IJRM 2016; 14 (3) :167-172
URL: http://ijrm.ir/article-1-737-en.html
Perinatal outcome in fresh versus frozen embryo transfer in ART cycles
Ali Aflatoonian1 , Mohammad Ali Karimzadeh Maybodi1 , Nastaran Aflatoonian1 , Nasim Tabibnejad2 , Mohammad Hossein Amir-Arjmand1 , Mehrdad Soleimani2 , Behrouz Aflatoonian1 , Abbas Aflatoonian * 3
1- Madar Hospital, Yazd, Iran
2- Infertility Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Infertility Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , abbas-aflatoonian@yahoo.com
Abstract:   (5108 Views)
Background: Despite of higher pregnancy rate after frozen embryo transfer (FET) which is accepted by the majority of researches, the safety of this method and its effect on neonatal outcome is still under debate.
Objective: The aim of this study was to evaluate pregnancy and neonatal outcome of FET compare to fresh cycles.
Materials and Methods: In this study,1134 patients using fresh ET and 285 women underwent FET were investigated regarding live birth as primary outcome and gestational age, birth weight, gender, multiple status, ectopic pregnancy, still birth and pregnancy loss as secondary outcomes.
Results: Our results showed that there is no difference between FET and fresh cycles regarding live birth (65.6% vs. 70.4% respectively). Ectopic pregnancy, still birth and abortion were similar in both groups. The mean gestational age was significantly lower among singletons in FET group compared to fresh cycles (p=0.047). Prematurity was significantly elevated among singleton infants in FET group (19.6%) in comparison to neonates born after fresh ET (12.8%) (p=0.037).
Conclusion: It seems that there is no major difference regarding perinatal outcome between fresh and frozen embryo transfer. Although, live birth is slightly increased in fresh cycles and prematurity was significantly increased among singleton infants in FET group.
Keywords: Frozen-thawed embryo transfer, Fresh embryo transfer, Perinatal outcome, Pregnancy outcome
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Type of Study: Original Article |
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