Showing 3 results for حاتمی
Sahar Hatami, Saeed Zavareh, Mojdeh Salehnia, Taghi Lashkarbolouki, Mohammad Taghi Ghorbanian, Isaac Karimi,
Volume 12, Issue 1 (2-2014)
Abstract
Background: Cryopreservation of ovarian tissues and pre-antral follicles is a promising prospect for preservation of women fertility.
Objective: The aim of this study was to evaluate the in vitro developmental competence of mouse vitrified pre-antral follicles in comparison to isolated pre-antral follicles derived from vitrified ovaries in the presence of alpha lipoic acid (ALA).
Materials and Methods: Pre-antral follicles derived from fresh, vitrified-warmed ovarian tissues and vitrified–warmed pre-antral follicles were cultured individually with or without ALA, followed by adding hCG to induce ovulation. The follicle growth, oocyte maturation, and embryo development were assessed.
Results: The diameter and development of follicles, oocyte maturation and embryo development rates were significantly higher in ALA supplemented groups compared to the respective ALA-free conditions groups. Aforementioned parameters were significantly higher in vitrified-warmed follicles in comparison to follicles derived from vitrified-warmed ovaries.
Conclusion: These findings support a superior performance of pre-antral follicles when vitrified rather than when isolated from vitrified ovaries with regard to increasing the rates of developmental parameters. Moreover, ALA improves the in vitro maturation of pre-antral follicles in vitrified and non-vitrified samples.
Behnaz Molaei, Farnaz Mohmmadian, Maryam Eftekhar, Robabeh Hatami, Atefe Tirkan, Mahsa Kiani,
Volume 15, Issue 2 (3-2017)
Abstract
Background: Chlamydia trachomatis and Neisseria gonorrhoeae are the most prevalent bacterial sexually transmitted diseases (STDs) in women.
Objective: The purpose of this study was to investigate the prevalence ofgGonorrheal and cChlamydial infections, and determination of related risk factors inmarried women complaining about vaginal discharge attending gynecological OPDin Zanjan in 2013-2014.
Materials and Methods: In this descriptive/analytic study, 100 women aged 18-49years with vaginal discharge were evaluated for signs and symptoms of gonococcaland chlamydial infections through interviews. Then cervical discharge samples andblood samples were collected from each subject for the detection of Nisseriagonorrhea and Chlamydia trachomatis by bacterial culture and serological tests,respectively. The data from the questionnaires and experimental tests werestatistically analyzed.
Results: The overall prevalence of Chlamydia trachomatis and Nisseria gonorrhoeae were 16% and 4%, respectively. There was no significant relationship between the history of fertility and childbirth, contraception methods, previous history of vaginal infections, previous history of urinary tract infections, number of coitus per weekly and self-reported symptoms (itching, burning, abdominal pain) with incidence of Nisseria gonorrhoeae and Chlamydia trachomatis.
Conclusion: According to results obtained through laboratory tests, the prevalence of gonococcal and chlamydial infections increased, which makes it necessary to put emphasis on education and further preventive and therapeutic programs.
Heresh Moridi, Seyed Abdolhakim Hosseini, Hossein Shateri, Nejat Kheiripour, Arastoo Kaki, Mahdi Hatami, Akram Ranjbaran,
Volume 16, Issue 4 (April 2018)
Abstract
Background: Malathion is an organophosphorus pesticide that commonly used in many agricultural and non-agricultural processes. Previous studies have reported the effects of melatonin on the reproductive system. Cerium dioxide nanoparticles (CeNPs) due to their antioxidative properties are promising to impact on the development of male infertility.
Objective: The aim of this study was to evaluate the effect of CeNPs on oxidative stress and sperm parameters after malathion exposure of male rats.
Materials and Methods: 36 adult male Wistar rats were divided into 6 groups (n=6/each): Control, CeNPs -treated control (15 and 30 mg/kg/day), malathion (100 mg/ kg/day), and CeNPs -treated malathion groups (15 and 30 mg/ kg/day). At the end of the study (4 wk), the sperm counts, motility, and viability in the testis of rats were measured, also lipid peroxidation, total antioxidant capacity, and total thiol groups in homogenate testis were investigated.
Results: Malathion significantly reduced sperm count, viability, and motility than the control rats (p<0.001). Co-treatment of malathion with CeNPs 30 mg/kg had a protective effect on sperm counts (p=0.03), motility (p=0.01), and viability (p<0.001) compare to malathion group. Also, the results showed that malathion reduced testis total anti-oxidant capacity, the total thiol group, and increased testis malondialdehyde than the control rats (p<0.001). CeNPs 30 mg/kg are increased total antioxidant capacity (p<0.001) and total thiol group (p=0.03) compared to malathion group. CeNPs at both doses (15 and 30 mg/kg) improved malondialdehyde than the malathion group (p<0.001 and p=0.01 respectively).
Conclusion: CeNPs 30 mg/kg administered considerably restored testicular changes induced by malathion. The improvement of oxidative stress by CeNPs may be associated with increased sperm counts, motility and viability in the testis.
