Showing 12 results for ایران.
Maryam Dalili, Mohamad Ali Karimzadeh Meybodi, Mohamad Ghaforzadeh, Tahmineh Farajkhoda, Hossein Molavi-E Vardanjani,
Volume 11, Issue 4 (6-2013)
Abstract
Background: Spontaneous preterm labor is one of the common obstetrics problems causing several physical, psychological and economical outcomes. Although due to these outcomes and the efficacy of cares for decreasing them, preterm labor screening is cost-effective and it is still one of the challenging issues in obstetrics.
Objective: In this study preterm labor screening by using cervical transvaginal sonography was evaluated.
Materials and Methods: This observational cohort study was performed in Yazd, Iran. Samples were selected from pregnant women at gestational age of 21-24 weeks who had single live fetus and referred to the obstetrics clinics of two selected hospitals in Yazd. Gestational age was estimated based on the sonography of the first trimester and cervical length measured by transvaginal sonography. Data analysis was done by using t and x2 test as well as ANOVA. Statistical significant level was considered as p<0.05.
Results: From 450 participants, 47 cases had preterm labor and 6 cases had positive funneling. Mean age of women with term labor was 26.09±4.13 years and that of women with preterm labor was 26.7±3.51 years (p=0.334). Duration of pregnancy and cervical length significantly differed between women with and without funneling (p=0.001). The sensitivity and specificity of screening based on cervical length of 25mm were 55.5% (50.9-60.1%) and 93.6% (91.2-96%) respectively.
Conclusion: Based on the results of the present study, transvaginal ultrasound assessment of cervical length in low risk women has an acceptable reliability for screening of preterm labor.
Ladan Haghighi, Marzieh Nojomi, Behnaz Mohabbatian, Zahra Najmi,
Volume 11, Issue 12 (1-2013)
Abstract
Background: Preterm birth (PTB) is responsible for 70% of neonatal mortalities. Various factors influence the risk of neonatal mortality in different populations.
Objective: Our objective was to evaluate neonatal survival rate of preterm infants, and to define its predictors in Iranian population.
Materials and Methods: This retrospective cohort study included all preterm (26-37 weeks) infants (n=1612) born alive in Shahid Akbar-abadi university hospital, during one year period (April 2010-2011). These infants were evaluated for fetal-neonatal, maternal, and pregnancy data. Survival analysis was performed and viability threshold and risk factors of neonatal mortality were evaluated.
Results: Total overall mortality rate was 9.1%. Survival rate were 11.11% for extremely low birth weights (LBW) and 45.12% for very early PTBs. The smallest surviving infant was a 750 gr female with gestational age (GA) of 30 weeks and the youngest infants was a 970 gram female with GA of 25weeks plus 2 days. History of previous dead neonate, need to cardio-pulmonary resuscitation (CPR), need to neonatal intensive care unit (NICU) admission, postnatal administration of surfactant, presence of anomalies, Apgar score <7, multiple pregnancy, non-cephalic presentation, early PTB, very early PTB, LBW, very low birth weight (VLBW) and extremely low birth weight (ELBW), were risk factors for mortality in preterm neonates.
Conclusion: Our study revealed that neonatal survival rate is dramatically influenced by birth weight especially under 1000grams, GA especially below 30 weeks, neonatal anomalies, history of previous dead fetus, multiple pregnancy, non- cephalic presentation, and need for NICU admission, resuscitation and respiratory support with surfactant
Katayon Vakilian, Mehdi Ranjbaran, Mahboobeh Khorsandi, Naser Sharafkhani, Mahmoud Khodadost,
Volume 13, Issue 12 (12-2015)
Abstract
Objective Background: Preterm labor, which defines as live-birth delivery before 37 weeks of gestation is a main determinant of neonatal morbidity and mortality around the world. : The aim of this study was to determine the prevalence of preterm labor in Iran by a meta-analysis study, to be as a final measure for policy makers in this field. Materials and Methods: In this meta-analysis, the databases of Thomson database (Web of Knowledge), PubMed/Medline, Science Direct, Scopus, Google Scholar, Iranmedex, Scientific Information Database (SID), Magiran, and Medlib were searched for articles in English and Persian language published between 1995 and 2014. Among the studies with regard to the inclusion and exclusion criteria, 14 studies (out of 1370 publications) were selected. Data were analyzed by using Stata software version 11. The heterogeneity of reported prevalence among studies was evaluated by the Chi-square based Q test and I2 statistics. Results: The results of Chi-square based on Q test and I2 statistics revealed severe heterogeneity (Q=2505.12, p-value < 0.001 and I2= 99.5%) and consequently, the random effect model was used for the meta-analysis. Based on the random effect model, the overall estimated prevalence of preterm in Iran was 9.2% (95% CI: 7.6 – 10.7). Conclusion: Present study summarized the results of previous studies and provided a comprehensive view about the preterm delivery in Iran. In order to achieve a more desirable level and its reduction in the coming years, identifying affecting factor and interventional and preventive actions seem necessary.
Seyed Alireza Afshani, Ali Mohammad Abdoli, Mehrieh Hashempour, Maryam Baghbeheshti, Mohammad Zolfaghari,
Volume 14, Issue 12 (12-2016)
Abstract
Background: Knowledge about assisted reproductive techniques (ART) and its procedures affect the attitude of infertile people. Making decisions about the use of ART is affected by one's perception and attitude.
Objective: The aim of this cross-sectional study was to determine the attitude of infertile couples toward applying ART, and to investigate its related factors.
Materials and Methods: A randomized cross-sectional study was conducted on 184 infertile couples who had referred to the Research and Clinical Center of Infertility, Yazd, Iran for diagnosis and treatment in June 2014. The data was collected using a two-part questionnaire containing demographic and attitudinal statements. For data analysis, SPSS statistical software and statistical tests of mean differences (t-test), Pearson correlation and analysis of variance were used.
Results: A significant relationship between spouse's attitude (p<0.01), relative's attitude (p<0.01), the applied knowledge of ART (p<0.01), and attitude of infertile couples toward applying the ART was observed; however, there was not any significant relationship between gender and socioeconomic status toward applying ART (p>0.05).
Conclusion: In conclusion, making a decision and accepting ART can be influenced by couple's attitude, their family's attitude and applied knowledge of ART
Tahmineh Farajkhoda,
Volume 15, Issue 2 (3-2017)
Abstract
Conducting research on the stem cell lines might bring some worthy good to public.Human Stem Cells (hSCs) research has provided opportunities for scientificprogresses and new therapies, but some complex ethical matters should be noticed toensure that stem cell research is carried out in an ethically appropriate manner. Theaim of this review article is to discuss the importance of stem cell research, code ofethics for stem cell research in Iran and ethical recommendation. Generation of stemcells for research from human embryo or adult stem cells, saving, maintenance andusing of them are the main ethical, legal and jurisprudence concerns in Iran.Concerns regarding human reproduction or human cloning, breach of humandignity, genetic manipulation and probability of tumorogenisity are observed inadult/somatic stem cells. Destruction of embryo to generate stem cell is an importantmatter in Iran. In this regards, obtaining stem cell from donated frozen embryosthrough infertility treatment that would be discarded is an acceptable solution in Iranfor generation of embryo for research. Ethical , legal, and jurisprudence strategiesfor using of adult/somatic stem cells are determination of ownership of stem cells,trade prohibition of human body, supervision on bio banks and information ofOversight Committee on Stem Cell Research. Recommendations to handle ethicalissues for conducting stem cell research are well-designed studies, compliance codesof ethics in biomedical research (specifically codes of ethics on stem cell research,codes of ethics on clinical trials studies and codes of ethics on animals studies),appropriate collaboration with ethics committees and respecting of rights ofparticipants (including both of human and animal rights) in research. In addition,there is a necessity to for extending global networks of bioethics for strengtheningcommunications within organizations at both the regional and international level,strengthening legislation systems, designing and establishing convenientcollaborative educational courses at different levels.
Sahar Moghbelinejad, Hossein Mozdarani, Pegah Ghoraeian, Reihaneh Asadi,
Volume 16, Issue 3 (3-2018)
Abstract
The male factor contributes to 50% of infertility. The cause of male infertility is idiopathic and could be congenital or acquired. Among different factors which are involved in idiopathic male infertility, genetic factors are the most prevalent causes of the disease. Considering, the high prevalence of male infertility in Iran and the importance of genetic factors in the accession of it, in this article we reviewed the various studies which have been published during the last 17 yr on the genetic basis of male infertility in Iran. To do this, the PubMed and Scientific information database (SID) were regarded for the most relevant papers published in the last 17 yr referring to the genetics of male factor infertility using the keywords „„genetics‟‟, “cytogenetic”, „„male infertility”, and “Iranian population”. Literatures showed that among the Iranian infertile men Yq microdeletion and chromosomal aberrations are two main factors that intervene in the genetics of male infertility. Also, protamine deficiency (especially P2) is shown to have an influence on fertilization rate and pregnancy outcomes. The highest rate of sperm DNA damages has been found among the asthenospermia patients. In several papers, the relation between other important factors such as single gene mutations and polymorphisms with male infertility has also been reported. Recognition of the genetic factors that influence the fertility of Iranian men will shed light on the creation of guidelines for the diagnosis, consultation, and treatment of the patients."
Seyedeh-Fatemeh Hekmatzadeh, Fatemeh Bazarganipour, Nazafarin Hosseini, Helen Allan, Somayeh Jalali, Zahra Abbasian, Akram Barani, Fereshteh Balochi, Saeideh Khademi, Tahereh Mahmoudi, Roghayeh Niknam, Zahra Khashavi, Seyed Abdolvahab Taghavi,
Volume 16, Issue 3 (3-2018)
Abstract
Background: Clinical measurement of quality of life (QoL) for assessing reproductive problems should be considered as a standard investigation at the initial and continuing medical consultations with infertile people.
Objective: The purpose of this study was comprehensive testing the psychometric properties of the Iranian version of fertility quality of life (FertiQoL).
Materials and Methods: This cross-sectional study was conducted on300 women referred to infertility clinic. After linguistic validation, a semi-structured interview was conducted to assess face validity. Consequently exploratory factor analysis was performed to indicate the scale constructs. Discriminate validity was assessed using the known groups comparison. Convergent validity was evaluated by assessing the correlation between similar content on the 12-Item Short Form Health Survey (SF12), Hospital Anxiety and Depression Scale and FertiQol. In addition, reliability analysis was carried out with internal consistency.
Results: The reliability of the Iranian version of the FertiQoL was satisfactory in all dimensions (0.77-0.83). Six factors (emotional, mind/body, relational, social, environmental, and tolerability) were extracted from the results of exploratory factor analysis. Discrimination validity showed that FertiQoL can differentiate between female patients with differing duration of infertility and number of children. Moreover, the results of convergent validity showed a favorable correlation between the related dimensions of SF12 (0.43-0.68), Hospital Anxiety and Depression Scale (0.47-0.52) and FertiQoL.
Conclusion: The Iranian version of FertiQoL is valid and reliable for assessing infertility problems and the effects of treatment on QoL of infertile patients referred for diagnosis and treatment at infertility clinic.
Masoud Mirzaei, Nasim Namiranian, Behnam Bagheri-Fahraji, Somaye Gholami,
Volume 18, Issue 9 (9-2020)
Abstract
Background: Changes in the state of energy balance owing to changes in physical activity (PA) may affect the reproductive system.
Objectives: the aim of this study was to assess the association between PA and infertility of women living in Yazd 2014 - 2015.
Materials and Methods: The study method was analytical cross-sectional on the Yazd Health Study (YaHS) data which was conducted on 10,000 people. We studied 2,611 women (20 and 49 yrs old), living in Greater Yazd area. PA information was collected using a physical activity questionnaire (IPAQ) short form. The standardized instruments were used for anthropometrics measurement.
Results: Totally 135 cases of infertility were documented. The overall prevalence of infertility was 4.73% (95% CI: 3.94-5.59%). The median of PA scores (METs) in women was 746.66 and 25-75% interquartile range was 361.25-1277.25. The relationship according to the Chi-square test between infertility and PA, as categorized variables, was significant (p = 0.015). It showed over 90% of those who suffered from infertility had a low or moderate PA.
Conclusion: The results of our study showed that there is a significant relationship between infertility and PA level in women living in Greater Yazd area. Also, women with infertility had lower activity levels, consistent with most previous studies.
Marzieh Azizi, Mahsa Kamali, Forouzan Elyasi, Mahboobe Shirzad,
Volume 19, Issue 5 (5-2021)
Abstract
Background: Due to the fear of childbirth (FOC) and failure to provide painless delivery in Iran, the prevalence rate of elective Cesarean section (C-section) performed on request by pregnant women is on the rise. However, no systematic review assessing the results of studies in this respect has been thus far developed.
Objective: To systematically review published psychological intervention research reflecting on FOC in Iran.
Materials and Methods: In this systematic review, the databases of PubMed, MEDLINE, PsycINFO, Wiley, ISI Web of Science, Scopus, Science Direct, Cochrane Library, Google Scholar, and Scientific Information Database were searched to retrieve the relevant studies. Manual searches were performed to find the relevant articles and finally 21 intervention studies were reviewed.
Results: Based on the modified Jadad Scale, a methodological quality (risk of bias) assessment tool, 14 and 7 studies had acceptable or good and low quality, respectively. Of the included articles, fear, fear of childbirth, pregnancy, psychological intervention, Iran. Cognitive behavioral therapy, relaxation techniques, psychological counseling, childbirth preparation classes (CPCs), mindfulness programs, and psychoeducation had been also practiced as the main types of psychological interventions for reducing FOC in pregnant women.
Conclusions: There was no clear evidence to establish the most effective method for minimizing levels of FOC in pregnant women. Based on the assessment tool and since most of the studies had moderate or low quality, conducting standard and high-quality randomized controlled trials focusing on FOC in pregnant women is of most importance in Iranian population.
Fatemeh Keikha, Ensieh Shahrokh Tehraninejad, Marzieh Rakhshkhorshid, Malihe Afiat, Fedyeh Hagholahi, Fatemeh Ghasemi,
Volume 20, Issue 1 (1-2022)
Abstract
Background: Betatrophin may be associated with metabolic diseases.
Objective: To investigate the betatrophin level and its association with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome (PCOS) and other infertile women during the intrauterine insemination cycle.
Materials and Methods: This case-control study was conducted with 90 infertile women (45 with PCOS and 45 without) chosen by convenience sampling, in the infertility clinic of Imam Khomeini Hospital in Tehran, Iran. Participants were interviewed to obtain their age, body mass index, and reproductive history. Fasting brachial venous blood samples were obtained on the 3rd day of the menstrual cycle to measure the levels of betatrophin, fasting blood sugar, insulin, luteinizing hormone, follicle-stimulating hormone, low-density lipoprotein cholesterol, estradiol, and high-sensitivity C-reactive protein.
Results: The results showed that the level of betatrophin in women with PCOS was significantly higher than in the control group (p = 0.05). Based on multiple linear regression analyses, the effects of metabolic and inflammatory parameters on betatrophin were not significant (p = 0.19). The results showed no significant difference between groups in folliculogenesis (p = 0.57).
Conclusion: According to the results, betatrophin levels were higher in infertile women with PCOS than in those without. The findings suggest that there may be an association between increased betatrophin and increased incidence of PCOS. Further studies with a larger sample size are needed to investigate the role of betatrophin in insulin resistance and lipid metabolism, and its effects on infertility treatment outcomes.
Arezou Omidvar, Malek Mirhashemi, Habib Yousefi, Effat Merghati Khoei,
Volume 20, Issue 11 (11-2022)
Abstract
Background: Sexual scripts (SSs) are formed based on the gendered culture in societies.
Objective: To evaluate the associations between the sexual behavioral aspects: capacity, motivation, performance, and SS amongst Iranian college students.
Materials and Methods: From September 2020 to December 2020, we recruited 400 college students who were married, had no acute or chronic diseases, was no drug abuser, and were not pregnant at the time of the study. The demographic questionnaire, sexual behavior assessment, and SSs questionnaires were completed by all the participants. Descriptive statistics and inferential statistics, Pearson correlation coefficient, and multivariate regression were used for data analysis. We also employed an independent t test to compare sexual behavior-related variables: sexual capacity, sexual performance, sexual motivation, and SSs in 2 female and male student groups.
Results: Men and women were significantly different in the component of sexual behaviors. Women had higher sexual motivation than men. The participants’ SSs were positively correlated with all 3 components of sexual behaviors at a significant level of p ≤ 0.001. Of demographic characteristics, only women’s age had a significant correlation with sexual capacity. For men, education level and economic status were positively correlated with all components of men’s sexual behaviors.
Conclusion: Sexual behaviors seem to be highly gendered, particularly, in the motivational component. Based on the results, SSs are more determinant than demographics. We recommend gender-sensitive and cultural-oriented sexuality educations for Iranians to provide fundamental changes in the SSs.
Mohammad Ranjbar, Ali Mohammad Abdoli, Tahereh Shafaghat, Hasan Jafari, Golnaz Izadpanah, Yibeltal Assefa,
Volume 21, Issue 10 (10-2023)
Abstract
Background: Infertility is one of the critical health issues in Iran. There are more than 70 specialized infertility treatment centers in Iran, of which the Yazd Reproductive Sciences Institute, is one of the most important ones.
Objective: This study aimed to determine the factors influencing infertile couples' choice of Yazd Reproductive Sciences Institute.
Materials and Methods: This cross-sectional study was conducted on 275 infertile couples aged 18 and older, referring to Yazd Reproductive Sciences Institute, Yazd, Iran from September 2021 to March 2022. Data were gathered using a 2-part questionnaire. Data analysis was done through SPSS software. We used descriptive statistics, Kruskal-Wallis, Mann-Whitney, and t test for data analysis.
Results: Most participants were individuals who came from other provinces of Iran (74.9%) and were referred to the Yazd Reproductive Sciences Institute. Among the 4 categories that influenced couples' decision to choose this center, factors related to the personnel and treatment staff received the highest score (75.83), while personal factors received the lowest score (65.76). The average score for factors related to doctors was 72.90, and for factors related to the center, it was 73.65. The satisfaction with personnel and treatment staff varied based on participants' education levels, with those who had lower levels of education reporting higher levels of satisfaction (p < 0.001).
Conclusion: The primary factors contributing to the success of the Yazd Reproductive Sciences Institute in attracting clients were the dedication and expertise of the staff, as well as the esteemed reputation of the doctors at the center.
