Showing 3 results for زنان نابارور
Cyrus Azimi, Malihea Khaleghian, Farideh Farzanfar,
Volume 11, Issue 4 (6-2013)
Abstract
Background: The infertility is an important health problem, affecting about 15% of couples. The important role of genetic factors in pathogenesis of infertility is now increasingly recognized. The value of karyotyping women in the routine work-out of couples referred for sterility has long been recommended.
Objective: The aim of this study was to define the frequency of all chromosomal aberrations among women which referred to our department due to infertility during the 21-year period.
Materials and Methods: In this 21-year retrospective study, for the first time, we investigated 896 women which referred to our department due to infertility during 1986 to 2006. For chromosome analysis, heparinized peripheral blood samples were cultured, harvested and banded according to standard methods.
Results: Out of 896 patients, 710 patients (79.24%) had a normal karyotype, and 186 patients (20.76%) showed abnormal karyotype. Among the abnormal ones 48 patients (25.81%) showed Turner's syndrome (45,X), and 45 patients (24.19%) were sex reversal with 46,XY karyotype. The rest of 93 patients (50%) revealed a wide range of chromosome abnormalities.
Conclusion: Our results emphasized the importance of the standard cytogenetic methods in assessing the genetic characteristics of infertile females, which allows detecting a variety of somatic chromosome abnormalities, because some of these may interfere with the success of reproduction.
Zahra Shayan, Zahra Pourmovahed, Fatemeh Najafipour, Ali Mohammad Abdoli, Fatemeh Mohebpour, Sedighe Najafipour,
Volume 13, Issue 12 (12-2015)
Abstract
Background: Nowadays, infertility problems have become a social concern, and are associated with multiple psychological and social problems. Also, it affects the interpersonal communication between the individual, familial, and social characteristics. Since women are exposed to stressors of physical, mental, social factors, and treatment of infertility, providing a psychometric screening tool is necessary for disorders of this group. Objective: The aim of this study was to determine the factor structure of the general health questionnaire-28 to discover mental disorders in infertile women. Materials and Methods: In this study, 220 infertile women undergoing treatment of infertility were selected from the Yazd Research and Clinical Center for Infertility with convenience sampling in 2011. After completing the general health questionnaire by the project manager, validity and, reliability of the questionnaire were calculated by confirmatory factor structure and Cronbach's alpha, respectively. Results: Four factors, including anxiety and insomnia, social dysfunction, depression, and physical symptoms were extracted from the factor structure. 50.12% of the total variance was explained by four factors. The reliability coefficient of the questionnaire was obtained 0.90. Conclusion: Analysis of the factor structure and reliability of General Health Questionnaire-28 showed that it is suitable as a screening instrument for assessing general health of infertile women.
Mahtab Sattari, Mehdi Ghiami Rad, Aaliye Ghasemzadeh, Zahra Mohammadoghli Reihan,
Volume 15, Issue 1 (1-2017)
Abstract
Background: Infertility is one of the major issues in society and its incidence is estimated to be almost 10-15%.. Chlamydia is an important cause of sexually transmitted diseases leading to infertility.
Objective: This study was designed to determine the frequency of anti-Chlamydia trachomatis (anti-C. trachomatis) antibodies in infertile women at Alzahra hospital, Tabriz, Iran.
Materials and Methods: In this cross-sectional study, the blood samples were collected randomly from 184 infertile women (case group) and 100 pregnant women (control group).the frequency of specific IgG and IgM anti-Chlamydia trachomatis antibodies were evaluated using ELISA.
Results: The frequency of anti-C. trachomatis IgG in pregnant and infertile women was 18% and 35.88%, respectively. The frequency of anti- C. trachomatis IgM in pregnant and infertile women was 2% and 5.44%.Our results showed the significant high rate of anti-Chlamydia trachomatis IgG (p=0.035), IgM (p=0.004) (p<0.05) in infertile women. Also, no significant relation was seen in the frequency of antibody between urban and rural women, IgG (p=0.690), IgM (p=0.486). The highest prevalence of positive cases was seen among the 21-30 years of age groups. There was not a significant relationship between age of infertile women and the amount of anti-Chlamydia trachomatis antibody, IgG (p=0.437), IgM (p=0.132). There was no significant relationship between tubal factor infertility and the frequency of anti C. trachomatis antibodies, IgG (p=0.208), IgM (p=0.082) (p>0.05).
Conclusion: According to the high frequency of antibody anti-C. trachomatis among infertile women in competition to the control group, evaluation and treatment of Chlamydia infections is necessary in these patients.
