en حاملگی خودبخودی بعد از درمان طبی و جراحی در نازایی: یک مطالعه مقطعی Fertility & Infertility Original Article Original Article <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مقدمه: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نازایی به دنبال علل مختلف از جمله زنانه و مردانه و هر دو و بدون علت است که با درمان طبی و جراحی مدیریت می&shy;شود. </span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">هدف: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">هدف از این مطالعه تعیین ارتباط وقوع حاملگی خودبخودی با فاکتورهای موثر در نازایی است.</span></span><strong><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span></strong><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مواد و روش &shy;ها: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">این مطالعه در دو مرکز نازایی در جنوب غرب ایران از فروردین 1395 تا فروردین 1396 انجام شده است. مطالعه به صورت مقطعی و مرور مدارک پزشکی در 655 زوج نازا انجام شده است. بیماران به دو گروه با و بدون حاملگی خودبخود به ترتیب 31 و 624 زوج تقسیم شدند. متغیرهای مورد مطالعه شامل سن زن و مرد</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مصرف سیگار</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">شغل مرد</span></span><span style="font-family:B Nazanin;">،</span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"> محل زندگی</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">علل نازایی</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نوع و مدت نازایی و زیرگروه&shy;های علل نازایی است.</span></span><strong><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span></strong><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نتایج: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نازایی با علت مردانه و زنانه، و زنانه به تنهایی و مردانه به تنهایی و با علت نامعلوم به ترتیب 5/47 و 5/31 و 5/14 و 6/6% است. میزان حاملگی خودبخودی 7/4 % است که ارتباط معنی&shy;داری با سن زن</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مدت نازایی</span></span><span style="font-family:B Nazanin;">،</span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"> نازایی غیرقابل توجیه و شغل همسر داردکه به ترتیب 036/0 </span></span><span style="font-size:10.0pt;">=</span><span dir="LTR"><span style="font-size:10.0pt;">p </span></span><span style="font-family:B Nazanin;">،</span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"> 01</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">/0 </span></span><span style="font-size:10.0pt;">= </span><span dir="LTR"><span style="font-size:10.0pt;">p</span></span><span style="font-family:B Nazanin;">،</span><span style="font-family:B Mitra;"><span style="font-size:10.0pt;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;</span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">001/0 </span></span><span style="font-size:10.0pt;">= </span><span dir="LTR"><span style="font-size:10.0pt;">p</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">و 004/0 </span></span><span style="font-size:10.0pt;">= </span><span dir="LTR"><span style="font-size:10.0pt;">p</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">است.</span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نتیجه&shy; گیری: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">شانس حاملگی خودبخودی در زوج&shy;های نازا با سن زن</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مدت نازایی</span></span><span style="font-family:B Nazanin;">، </span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نازایی غیرقابل توجیه و شغل همسر ارتباط دارد.</span></span><br> &nbsp;<br> <strong><em><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:10.0pt;"></span></span></span></em></strong> <p style="margin: 0px; line-height: 200%;"><strong>Background:</strong> The phenomenon of infertility may be derived from different factors - either in males or females or both genders, including few unexplained factors. It is generally managed by medical and surgical treatments.<br> <strong>Objective: </strong>To find a relation of occurrence of spontaneous pregnancy (SP) with effective factors in infertility.<br> <strong>Materials and Methods:</strong> This cross-sectional study was conducted at two referral infertility centers (university and privacy center) in the southwest of Iran from March 2015 and March 2016 on 655 infertile couples, who were divided in two groups of with (n = 31) and without (n = 624) SP. The variables included female and male age, male smoking, male job, the place of living, the causes of infertility, the type and duration of infertility, and the subgroups of infertility causes.<br> <strong>Results:</strong> Infertility may be caused due to both male- and female- related factors (47.5%). While female-related infertility was found in 31.5%, male-related infertility in 14.5%, and infertility due to unexplained factors in 6.6% of our patients. The rate of SP was 4.7%, which had a significant relation with the duration of infertility (p = 0.01), with women&rsquo;s age (p = 0.048), unexplained infertility (p = 0.001), and husband&#39;s job (p = 0.004).<br> <strong>Conclusion: </strong>The occurrence of SP in infertile couples was related to age of the female partner, the duration of unexplained infertility, and the male partner&#39;s job.</p> کلمات کلیدی: نازایی زنانه, نازایی مردانه, حاملگی خودبخودی, اپیدمیولوژی, اتیولوژی. Male infertility, Female infertility, Spontaneous pregnancy, Epidemiology, Etiology. 905 910 http://ijrm.ir/browse.php?a_code=A-10-934-1&slc_lang=en&sid=1 Nasrin Saadati saadatynasrin@gmail.com 0000-0003-1946-8386 No Department of Community Medicine, School of Medicine, Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Roshan Nikbakht rosnikba@yahoo.com 0000-0003-2347-8560 Yes Department of Obstetrics and Gynecology, Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Alireza Sattari alimds1386@yahoo.com 0000-0002-7462-4233 No Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Fatemeh Sadat Amininezhad amininejad.fateme@yahoo.com 0000-0002-2210-5757 No Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.