en بررسی ارتباط شاخص توده بدنی و پره اکلامپسی: بررسی مرور سیستماتیک و متاآنالیز Review article Review Article <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">مقدمه: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">یکی از عوامل مرگ و میر و ابتلا در مادر و جنین افزایش فشار خون در دوران بارداری است، شایع&shy;ترین نوع این اختلال پره&shy;اکلامپسی است که عوارض زیادی برای مادر و جنین دارد.</span></span><strong><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span></strong><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">هدف: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">هدف این مطالعه مرور سیستماتیک و متاآنالیز تعیین ارتباط بین پره&shy;اکلامپسی و </span></span><span dir="LTR"><span style="font-size:10.0pt;">BMI</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">در ایران است.</span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">موارد و روش&shy;ها: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">با استفاده از کلید واژه&shy;های معتبر در پایگاه&shy;های جهاد دانشگاهی (</span></span><span dir="LTR"><span style="font-size:10.0pt;">SID</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">)، </span></span><span dir="LTR"><span style="font-size:10.0pt;">Pubmed</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">و </span></span><span dir="LTR"><span style="font-size:10.0pt;">Scopus</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> داده</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">های حاصل از مقالات چاپ شده بین &nbsp;&nbsp;&nbsp;سال&shy;های 2000 تا 2016 در ایران مورد بازبینی قرار گرفت. تحلیل داده&shy;ها با نرم افزاز </span></span><span dir="LTR"><span style="font-size:10.0pt;">stata ver</span></span> <span dir="LTR"><span style="font-size:10.0pt;">11.2</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">و با استفاده از مدل اثرات تصادفی صورت گرفت.</span></span><strong><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span></strong><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">تعداد کل نمونه در 16 مطالعه مورد بررسی، 5946 نفر با میانگین </span></span><span dir="LTR"><span style="font-size:10.0pt;">,BMI</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> 13/25، 42/27،</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">33/26 ²</span></span><span dir="LTR"><span style="font-size:10.0pt;">kg/m</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">درگروه&shy;های سالم، پره&shy;اکلامپسی خفیف و شدید به ترتیب ثبت شد.</span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتیجه &shy;گیری: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج این مطالعه نشان داد که بین </span></span><span dir="LTR"><span style="font-size:10.0pt;">BMI</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">و خطر پره</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">اکلامپسی رابطه معنی</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">داری وجود دارد، بنابراین می</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">توان گفت </span></span><span dir="LTR"><span style="font-size:10.0pt;">BMI</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بالا ممکن است یکی از راه</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">های تشخیص پره</span></span><span dir="LTR"><span style="font-family:arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">اکلامپسی باشد.</span></span> <strong>Background</strong>: One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.<br> <strong>Objective:</strong> The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.<br> <strong>Materials and Methods</strong>: Using valid keywords in the SID database, PubMed, Scopus,data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and<br> analyzed using STATA version 11.1.<br> <strong>Results</strong>: A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m2 in the healthy, mild, and severe preeclamptic groups, respectively.<br> <strong>Conclusion:</strong> The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia. پره اکلامپسی, BMI, ایران, متاآنالیز. Preeclampsia, Body mass index, Iran, Meta-analysis. 463 472 http://ijrm.ir/browse.php?a_code=A-10-1-636&slc_lang=en&sid=1 Morteza Motedayen 0000-0001-5849-1023 No Department of Cardiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Mohammad Rafiei rafeie@arakmu.ac.ir 0000-0001-7042-6654 Yes Department of Biostatistics and Epidemiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran. Mostafa Rezaei Tavirani 0000-0003-1767-7475 No Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Kourosh Sayehmiri 0000-0002-9742-770x No Psychosocial Injuries Research Center, Department of Biostatistics, School of Public Health, Ilam University of Medical Sciences, Ilam, Iran. Majid Dousti 0000-0002-7418-3861 No Injuries Research Center, Department of Biostatistics, School of Public Health, Ilam University of Medical Sciences, Ilam, Iran.