en اثر چرخش کاتتر در هنگام خروج آن بر روی نتایج انتقال جنین فریز شده Original Article Original Article <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">مقدمه: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">انتقال جنین آخرین و مهمترین مرحله</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">در سیکل&shy;های کمک باروری (</span></span><span dir="LTR"><span style="font-size:10.0pt;">ART</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">) است. پیشنهاد شده است که موکوس سرویکس به روش</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">&shy;</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">های مختلف با انتقال جنین تداخل می&shy;نماید. چند مطالعه نشان می&shy;دهد که چرخش کاتتر می&shy;تواند با آزاد کردن موکوس مانع جابه&shy;جایی جنین شود.</span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">هدف:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">در این مطالعه گذشته&shy;نگر، نتایج حاصل از انتقال جنین فریز شده (</span></span><span dir="LTR"><span style="font-size:10.0pt;">FET</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">) بر اساس چرخش کاتتر در هنگام خروج آن بررسی شد.</span></span><strong><span dir="LTR"><span style="font-size:11.0pt;"></span></span></strong><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">موارد و روش&shy;ها: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">در این مطالعه گذشته</span></span><span dir="LTR"><span style="font-size:11.0pt;">&shy;</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نگر مقطعی، پرونده بالینی 240 </span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">زن</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> که سیکل&shy;های </span></span><span dir="LTR"><span style="font-size:10.0pt;">FET</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">را تجربه کرده بودند، بررسی شد. افراد مورد مطالعه به دو گروه تقسیم شدند: گروه مورد </span></span><span dir="LTR"><span style="font-size:10.0pt;">A</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> 120 نفر چرخش کاتتر هنگام خروج آن انجام شد، و گروه کنترل </span></span><span dir="LTR"><span style="font-size:10.0pt;">B</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">120</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">نفر چرخش کاتتر انجام نشد. در پایان، حاملگی&shy;های کلینیکی و شیمیایی و میزان لانه&shy;گزینی بین دو گروه مقایسه شد.</span></span><strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;"></span></span></strong><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">ویژگی&shy;های بالینی و دموگرافیک اساسی دو گروه تفاوت معنی&shy;داری نداشتند. اختلاف معنی&shy;داری بین دو گروه از لحاظ میزان حاملگی شیمیایی (3/43</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">%</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">، در مقابل 7/21</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">%</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">، 001/0</span></span><span style="font-size:10.0pt;">=</span><span dir="LTR"><span style="font-size:10.0pt;">p</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">) مشاهده شد. علاوه بر این، در گروه مطالعه میزان حاملگی کلینیکی به طور معنی&shy;داری بیشتر (35/33</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">%</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> در مقابل 2/14</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">%</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">، 002/0</span></span><span style="font-size:10.0pt;">=</span><span dir="LTR"><span style="font-size:10.0pt;">p</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">) بود.</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"></span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتیجه&shy; گیری:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج تحلیل داده</span></span><span dir="LTR"><span style="font-size:11.0pt;">&shy;</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">ها در این تحقیق نشان داد که چرخش کاتتر هنگام خارج شدن، باعث افزایش لانه</span></span><span dir="LTR"><span style="font-size:11.0pt;">&shy;</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">گزینی و حاملگی بالینی می</span></span><span dir="LTR"><span style="font-size:11.0pt;">&shy;</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">شود.</span></span><strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;"></span></span></strong> <strong>Background:</strong> Embryo transfer (ET) is the last and the most clinical process in assisted reproductive technology cycle. It has been suggested that cervical mucus interacts with an adequate embryo transfer in different ways. A few studies showed that catheter rotation could discharge mucus entrapped in the embryo to neutralize embryo displacement.<br> <strong>Objective:</strong> The aim of this present study was to compare the outcome of frozen embryo transfer (FET) based on catheter rotation during withdrawal.<br> <strong>Materials and Methods: </strong>In this case-control study, the clinical documents of 240 women who experienced frozen embryo transfer cycles were reviewd. The subjects were divided into two groups (n = 120/each), including A) the rotation treatment group (360&deg;) that underwent ET using catheter rotation and B) the control group including the subjects who experienced ET with no catheter rotation. Clinical and chemical pregnancies and implantation rates were compared between two groups.<br> <strong>Results:</strong> Results showed that there is no significant difference between the basic clinical and demographic features of both groups (p > 0.05). A significant difference was observed in terms of the rate of chemical pregnancy between groups (21.7% vs 43.3%, p = 0.001 respectively). In addition, the rate of clinical pregnancy was significantly higher in study group than the control (33.35% vs 14.2%, p = 0.002 respectively).<br> <strong>Conclusion:</strong> Our results demonstrated that catheter rotation during withdrawal increased the implantation rate and clinical pregnancy. انتقال جنین, تکنیک کمک باروری, لانه گزینی, حاملگی. Embryo transfer, Assisted reproductive technique, Implantation, Pregnancy. 481 486 http://ijrm.ir/browse.php?a_code=A-10-1-638&slc_lang=en&sid=1 Maryam Eftekhar 0000-0003-3835-5635 No Yazd Reasearch and Clinical Center for Infertility, Yazd Reproductive Science Institute, Shahid Sadoughi University, Yazd, Iran Lida Saeed saeed6@yahoo.com 0000-0001-5865-4021 Yes Yazd Reasearch and Clinical Center for Infertility, Yazd Reproductive Science Institute, Shahid Sadoughi University, Yazd, Iran Masrooreh Hoseini 0000-0002-1696-7667 No Yazd Reasearch and Clinical Center for Infertility, Yazd Reproductive Science Institute, Shahid Sadoughi University, Yazd, Iran