International Journal of Reproductive BioMedicine
International Journal of Reproductive BioMedicine
IJRM
Medical Sciences
http://ijrm.ir
1
admin
2476-4108
2476-3772
10.29252/ijrm
en
jalali
1398
6
1
gregorian
2019
9
1
17
9
online
1
fulltext
en
مقایسه سطح سرمی تعدادی عناصر ضروری و ویتامین D بین بیماران با نشانگان پیش قاعدگی و کنترل نرمال: یک مطالعه مقطعی
Comparison of serum level of some trace elements and vitamin D between patients with premenstrual syndrome and normal controls: A cross-sectional study
Original Article
Original Article
<strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">مقدمه: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نشانگان پیش</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">قاعدگی (</span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">) یک مشکل عمومی در زنان است که با چندین نشانه عاطفی، روانی و فیزیکی طی فاز لوتئال مشخص می</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">شود اما این نشانه</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">ها در فاز فولیکولار کاهش می</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">یابند. تاکنون علت </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بخوبی شناخته نشده است. بسیاری از محققان پیشنهاد می</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">دهند که مصرف عناصر ضروری و ویتامین­ها می­توانند علائم </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">را کاهش دهند.</span></span><strong><span dir="LTR"><span style="font-size:11.0pt;"></span></span></strong><br>
<strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">هدف: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">هدف این مطالعه مقایسه سطح سرمی تعدادی از عناصر ضروری و ویتامین </span></span><span dir="LTR"><span style="font-size:10.0pt;">D</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بین کنترل نرمال و مبتلایان به نشانگان پیش</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">قاعدگی است.</span></span><strong><span dir="LTR"><span style="font-size:11.0pt;"></span></span></strong><br>
<strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">موارد و روش­ها: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">300 دانشجوی (19-21 ساله) اهل شهرستان فلاورجان بطور تصادفی انتخاب شده و پرسشنامه استاندارد </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">را طی سه سیکل قاعدگی تکمیل کردند. مبتلایان به </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بر اساس پرسشنامه تعیین شدند و دانشجویان به دو گروه تقسیم شدند: افراد سالم (کنترل) و افراد مبتلا به </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">. سپس سطح سرمی روی، آهن، کلسیم، منیزیوم، پتاسیم، سدیم و ویتامین </span></span><span dir="LTR"><span style="font-size:10.0pt;">D</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;"> اندازه­گیری و بین دو گروه مقایسه شد.</span></span><span dir="LTR"><span style="font-size:11.0pt;"></span></span><br>
<strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج: </span></span></strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتایج ما نشان داد که شیوع </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">حدود 5/41% بود. سطح سرمی ویتامین </span></span><span dir="LTR"><span style="font-size:10.0pt;">D</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">در هر دو گروه کاهش نشان داد اما این کاهش در گروه </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بطور معنی</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">داری کمتر بود (05/0 </span></span><span dir="LTR"><span style="font-size:10.0pt;">p≤</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">). سایر فاکتورها بین دو گروه کنترل و </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">تغییر معنی</span></span><span dir="LTR"><span style="font-size:11.0pt;">­</span></span><span style="font-family:b mitra;"><span style="font-size:11.0pt;">داری نشان نداد.</span></span><br>
<strong><span style="font-family:b mitra;"><span style="font-size:11.0pt;">نتیجه­ گیری:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">کمبود ویتامین </span></span><span dir="LTR"><span style="font-size:10.0pt;">D</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">احتمالا یکی از مهمترین دلایل علائم ناخوشایند </span></span><span dir="LTR"><span style="font-size:10.0pt;">PMS</span></span> <span style="font-family:b mitra;"><span style="font-size:11.0pt;">بین این دانشجویان می­باشد.</span></span>
<strong>Background: </strong>Premenstrual syndrome (PMS) is a common problem among women and is identified by reversal emotional, psychological, and physical signs during the luteal phase. These signs, however, lower down in the follicular phase. The cause of PMS isn't very well-known up to now Control group and many researchers have suggested that mineral compounds and vitamins can inhibit these symptoms<br>
<strong>Objective: </strong>The objective of this study is to compare the serum level of some trace elements and vitamin D between normal controls and patients with PMS.<br>
<strong>Materials and Methods: </strong>300 female students (19-21 yr old) from Falavarjan County were randomly selected and asked to complete a standard questionnaire on PMS during three menstruation cycles. The students were divided into two groups: healthy persons (control) and PMS persons, and PMS was determined on the basis of the answers to the questionnaire. Thereafter, the serum concentrations of zinc, iron, calcium, magnesium, potassium, sodium, and Vitamin D3 were measured and compared between the two groups. <span dir="RTL"></span><br>
<strong>Results:</strong> Our results showed that the PMS prevalence was about 41.5%. The level of vitamin D decreased in both the control and PMS groups, with a significantly lower range of vitamin D (p ≤ 0.05) in the PMS group. Other factors had no significant change between the two groups. <span dir="RTL"></span><br>
<strong>Conclusion: </strong>Vitamin D deficiency was probably one of the most important causes of unpleasant symptoms of PMS between these students.
نشانگان پیش قاعدگی, عناصر ضروری, ویتامین D
Premenstrual syndrome, Trace elements, Vitamin D.
647
652
http://ijrm.ir/browse.php?a_code=A-10-1-656&slc_lang=en&sid=1
Mahnoosh
Fatemi