en Original Article Original Article <strong>Background:</strong> Determination of oocyte and embryo quality are one of the most important goals in IVF. Anti-mullerian hormone (AMH) is secreted by the ovarian granulosa cells into blood flow and follicular fluid. Follicular fluid anti-mullerian hormone level is probably a marker of activity of granulose cells. <strong>Objective:</strong> To evaluate whether high level of follicular fluid anti-mullerian hormone level is related to success of fertilization and better embryo quality. <strong>Materials and Methods:</strong> 62 women, whose follicular fluid sample was obtained from a single follicle in each patient, underwent IVF with GnRH-agonist long protocol. Based on oocyte fertilization, the patients were divided into fertilized group (n=42) and non-fertilized group (n=20). FF AMH levels were measured in both groups and the quality of embryos was determined in fertilized group.<br> <strong>Results: </strong>Median of FF AMH level in fertilized group was higher than that in non-fertilized group (5.7ng/ml v.s. 2.7ng/ml) and a statistically significant difference was observed between the two groups. There was a significant difference between FF AMH level and scores of embryos (p<0.001). The medians levels of FF AMH were 6.7ng/ml in good quality embryos and 3.80ng/ml in fair quality embryos.<br> <strong>Conclusion:</strong> Our results indicate that FF AMH level has positive correlation with fertilization and embryo quality; therefore, it can be considered as a marker of IVF outcome. Anti-mullerian hormone, Follicular fluid, Fertilization, Embryo quality, In-vitro fertilization. 157 160 http://ijrm.ir/browse.php?a_code=A-10-549-195&slc_lang=en&sid=1 Abbas Aflatoonian No Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mehri Mashayekhy Dr.Mashayekhy@yahoo.com Yes Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Farnaz Mohamadian No Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Fatemeh Mansoori Moghaddam No Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran