en شیوع اختلال عملکرد جنسی در زنان مبتلا به سرطان: یک بررسی سیستماتیک و متاآنالیز Reproductive Oncology Review article Review Article <div style="text-align: justify;"><strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مقدمه:</span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"> سرطان یکی از بیماری&shy;های شایع است که پیامدهای جسمی و روانی بسیاری را به دنبال دارد. زنان مبتلا به سرطان بیشتر از زنان سالم دچار اختلال عملکرد جنسی می&shy;شوند.</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">هدف:</span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"> مطالعه حاضر با هدف تخمین شیوع کلی اختلال عملکرد جنسی در زنان مبتلا به سرطان انجام شده است.</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">مواد و روش &shy;ها: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">پایگاه&shy;های بین&shy;المللی</span></span><span dir="LTR"><span style="font-size:10.0pt;">Google Scholar </span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">،</span></span><span dir="LTR"><span style="font-size:10.0pt;">Embase</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">،</span></span><span dir="LTR"><span style="font-size:10.0pt;">PubMed</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">،</span></span> <span dir="LTR"><span style="font-size:10.0pt;">Web of Science</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">و</span></span><span dir="LTR"><span style="font-size:10.0pt;">Scopus</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">&nbsp;بدون محدودیت زمانی برای مقالات مرتبط جستجو شدند. در جستجو از کلمات کلیدی &quot;نئوپلازی&quot;، &quot;تومور&quot;، &quot;سرطان&quot;، &quot;بدخیمی&quot;، &quot;شاخص عملکرد جنسی زنان</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"> &quot;</span></span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">و &quot;اختلال عملکرد جنسی زنان&quot; استفاده شد. داده</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;">&shy;</span></span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">ها با استفاده از روش متاآنالیز و مدل اثرات تصادفی در نرم افزار</span></span><span dir="LTR"><span style="font-size:10.0pt;">Stata</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">، نسخه 14 تجزیه و تحلیل شد.</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;"></span></span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نتایج: </span></span></strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">تجزیه و تحلیل 24 مقاله با حجم نمونه 5483 نشان داد که شیوع اختلال عملکرد جنسی در زنان مبتلا به سرطان (59-74 </span></span><span dir="LTR"><span style="font-size:10.0pt;">CI:</span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">، 95</span></span><span style="font-family:Sakkal Majalla;"><span style="font-size:11.0pt;">٪</span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">) 66% است. بیشترین و کمترین شیوع به ترتیب در آفریقا</span></span> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">75% و اروپا 43% بود. هیچ ارتباطی بین شیوع اختلال عملکرد جنسی و سن، اندازه نمونه، سال انتشار و کیفیت مقالات وجود نداشت</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;">.</span></span></span><span style="font-family:B Mitra;"><span style="font-size:11.0pt;"></span></span><br> <strong><span style="font-family:B Mitra;"><span style="font-size:11.0pt;">نتیجه&shy; گیری:</span></span></strong> <span style="font-family:B Mitra;"><span style="font-size:11.0pt;">اختلال عملکرد جنسی در زنان مبتلا به سرطان بسیار شیوع دارد. ارائه آموزش&shy;های لازم برای حل این مشکل ضروری به نظر می&shy;رسد</span></span><span dir="LTR"><span style="font-family:Arial,sans-serif;"><span style="font-size:11.0pt;">.</span></span></span></div> <div style="text-align: justify;"><strong>Background:</strong> Cancer is one of the most common diseases and it has many physical and psychological consequences. Women with cancer are more likely to suffer from sexual dysfunction (SD) than healthy women.<br> <strong>Objective:</strong> To estimate the overall prevalence of SD in women with cancer.<br> <strong>Materials and Methods: </strong>The international databases Google Scholar, Embase, PubMed, Web of Science, and Scopus were searched for related articles without any time limitation. The keywords &ldquo;Neoplasia&rdquo;, &ldquo;Tumor&rdquo;, &ldquo;Cancer&rdquo;, &ldquo;Malignancy&rdquo;, &ldquo;Female Sexual Function Index&rdquo;, &ldquo;FSFI&rdquo;, and &ldquo;female sexual dysfunction&rdquo; along with their combinations were used in the search. Inconsistencies in the data were examined using the I² test. The data were analyzed using the meta-analysis method and the random-effects model in the Stata software.<br> <strong>Results: </strong>The analysis of 24 articles with a sample size of 5483 women showed that the prevalence of SD in women with cancer was 66<span dir="RTL">%</span> (95% CI: 59-74%). The highest and lowest prevalence were in Africa and Europe, respectively (75%; 95% CI: 66-83% vs. 43%; 95% CI: 26-60%, respectively). There was no relationship between the prevalence of SD and the mean age of the women, sample size, year of publication, or quality of articles.<span dir="RTL"></span><br> <strong>Conclusion:</strong> SD is highly prevalent in women with cancer. African and American women with cancer have a higher average FSD prevalence than Asian and European ones.</div> اختلال عملکرد جنسی, شیوع, متاآنالیز, زنان, رابطه جنسی. Sexual dysfunction, Prevalence, Meta-analysis, Women, Sex. 1 12 http://ijrm.ir/browse.php?a_code=A-10-1331-1&slc_lang=en&sid=1 Seyedeh Esmat Hosseini esmat.hosseini_110@yahoo.com 0000-0002-8938-1609 No Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mahnaz Ilkhani m_ilkhani@yahoo.com 0000-0002-7167-1632 Yes Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Cancer Research Center, Shahid Beheshati University of Medical Sciences, Tehran, Iran. Camelia Rohani cameliarohani@yahoo.com 0000-0002-6456-6586 No Department of Health Care Sciences, Palliative Care Center, Ersta Sköndal Bräcke University College, Campus Ersta, Stockholm, Sweden. Department of Community Health Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Alireza Nikbakht Nasrabadi nikbakht@tums.ac.ir 0000-0002-3970-4158 No School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. Raza Ghanei Gheshlagh rezaghanei30@yahoo.com 0000-0002-7414-8134 No Spiritual Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. Ashraf Moini ashraf.moieni@gmail.com 0000-0002-7114-8331 No Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran. Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. Department of Obstetrics and Gynecology, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran.