en مؤثرترین مداخلات در عملکرد و اختلال عملکرد جنسی افراد با مولتیپل اسکلروزیس: یک مرور سیستماتیک و متاآنالیز Reproductive Psycology Review article Review Article <div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">اختلال عملکرد جنسی در مولتیپل اسکلروزیس وابسته به عوامل متعددی است. با این وجود هیچ درمان قابل اعتمادی برای این چالش وجود ندارد.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف از انجام مطالعه، تعیین مداخلات مؤثر بر عملکرد جنسی یا اختلال عملکرد جنسی در افراد با مولتیپل اسکلروزیس بود.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مواد و روش&shy; ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">برای یافتن مطالعات مداخله&shy;ای منتشر شده مرتبط که حداقل دارای چکیده انگلیسی یا به زبان فارسی باشند، پایگاه داده&shy;های بین&shy;المللی آنلاین شامل </span></span>&nbsp;<span dir="LTR" style="font-size:10.0pt">Statistical Institute, PubMed, Scopus, Cochrane, Medline, PsycINFO, EMBASE, CINAHL Google Scholar</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">از ژانویه 1990 تا ژوئن 2021 جستجو شد. نتایج با استفاده از نرم&shy;افزار </span></span><span dir="LTR" style="font-size:10.0pt">RevMan 5.3</span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">تجزیه و تحلیل شد و 05/0 </span></span><span dir="LTR" style="font-size:10.0pt">p <</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> بعنوان سطح معنی&shy;داری در نظر گرفته شد. </span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">در بررسی اولیه 568 مقاله وارد شد، پس از حذف مقاله&shy;های تکراری و غیرمرتبط بر اساس داشتن اطلاعات اصلی، 41 مقاله باقی ماند. مطالعات بر اساس وجود یا عدم وجود علائم اختلال عملکرد جنسی در معیارهای ورود به مطالعه، به دو گروه عملکرد جنسی (27 مطالعه) و اختلال عملکرد جنسی (14 مطالعه) تقسیم شدند. مداخلات در هر گروه به چهار دسته که شامل مداخلات روان درمانی-آموزشی، ورزش و توانبخشی، طبی و مداخلات مختلط تقسیم شدند. بیش از نیمی از مداخلات روان درمانی-آموزشی بهبود قابل توجهی را بعد از اتمام مداخله در عملکرد جنسی نشان دادند (0003/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">). در مطالعات اختلال عملکرد جنسی، در بیشتر مداخلات (14/13 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">n</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">) حداقل یک زیر مقیاس اختلال عملکرد جنسی بهبود یافته بود. همچنین مداخلات طبی بر اختلال عملکرد جنسی مردان و مداخلات روان درمانی-آموزشی در عملکرد جنسی زنان تأثیر بیشتری داشتند.</span></span></span></span></span></span></span><br> <b><span dir="RTL" lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجه &shy;گیری: </span></span></b><span dir="RTL" lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مداخلات روان درمانی-آموزشی و طبی، متداول&shy;ترین نوع مداخلات مؤثر بر عملکرد و اختلال عملکرد جنسی بودند. مداخلات روان درمانی-آموزشی که به طور اختصاصی در زنان اجرا شده بودند و چهار مقاله&shy;ای که به طور اختصاصی در مورد درمان طبی مردان بودند، تأثیرات مثبتی را نشان دادند.</span></span></div> <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:normal"><span sans-serif=""><b><span style="font-size:12.0pt"><span new="" roman="" times="">Background:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" times=""> Sexual dysfunction has many factors in multiple sclerosis, but there is no reliable treatment for this challenge.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif=""><b><span style="font-size:12.0pt"><span new="" roman="" times="">Objective:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" times=""> Determining effective sexual function or dysfunction interventions in individuals with multiple sclerosis.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif=""><b><span style="font-size:12.0pt"><span new="" roman="" times="">Materials and Methods:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" times=""> To find the relevant published interventional studies that at least had an English abstract or in Persian, we searched International Statistical Institute, PubMed, Scopus, Cochrane, Medline, PsycINFO, EMBASE, CINAHL, and Google Scholar from January 1990 to June 2021. The results were analyzed using RevMan 5.3 software. The p < 0.05 was considered significant. </span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif=""><b><span style="font-size:12.0pt"><span new="" roman="" times="">Results:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" times=""> Out of 568 articles, 41 were included after deleting the duplicate and irrelevant articles. Studies were divided into 2 groups of sexual function (n = 27) and dysfunction (n = 14). Interventions in each category have 4 subgroups: psychoeducational, exercise and rehabilitation, and medical and multi-type interventions. For improving sexual function, more than half of psychoeducational interventions showed a significant improvement after interventions (p = 0.0003). In sexual dysfunction studies, most of the interventions (n = 13/14) had improved at least one subscale of sexual dysfunction. Medical interventions were effective on men&rsquo;s sexual dysfunction, and psychoeducational interventions had been more effective in women&rsquo;s sexual dysfunction.</span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><span style="font-family:Times New Roman;"><b><span style="font-size:12.0pt"><span new="" roman="" times="">Conclusion:</span></span></b></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="font-family:Times New Roman;"> Psychoeducational and medical interventions are the commonest effective interventions. T</span><span class="A0" minion="" pro="" style="font-family:"><span style="color:black"><span new="" roman="" style="font-family:" times=""><span style="font-family:Times New Roman;">he psychoeducational studies conducted specifically on women had a positive impact, and only 4 articles with medical interventions were specifically targeted at men, which had a positive effect.</span> </span></span></span></span></span></span></span></span><br> <span dir="RTL"></span></div> کارآزمایی بالینی, مولتیپل اسکلروزیس, اختلال عملکرد جنسی, مرور سیستماتیک. Clinical trial, Multiple sclerosis, Sexual dysfunction, Systematic review. 241 254 http://ijrm.ir/browse.php?a_code=A-10-1485-1&slc_lang=en&sid=1 Bahare Afshar bahar.afshar1372m@gmail.com 0000-0002-5296-8035 No Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. Leila Amini amini.l@iums.ac.ir 0000-0002-5758-9157 Yes Nursing Care Research Center (NCRC), Department of Midwifery, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. Maryam Hasani maryam.hassani50@gmail.com 0000-0002-2008-6732 No Department of Midwifery, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khoramabad, Iran. Shayesteh Jahanfar jahanfar2000@yahoo.com 0000-0001-6149-1067 No MPH Program, Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, USA. Seyed Massood Nabavi seyedmassoodnabavi@gmail.com 0000-0002-9814-8083 No Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Department of Brain and Cognitive Sciences, Cell Science Research Center, Royan Institute for Stem Cell, Tehran, Iran.