<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>International Journal of Reproductive BioMedicine</title>
<title_fa>International Journal of Reproductive BioMedicine</title_fa>
<short_title>IJRM</short_title>
<subject>Medical Sciences</subject>
<web_url>http://ijrm.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2476-4108</journal_id_issn>
<journal_id_issn_online>2476-3772</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.29252/ijrm</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid></journal_id_sid>
<journal_id_nlai></journal_id_nlai>
<journal_id_science></journal_id_science>
<language>en</language>
<pubdate>
	<type>jalali</type>
	<year>1401</year>
	<month>2</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2022</year>
	<month>5</month>
	<day>1</day>
</pubdate>
<volume>20</volume>
<number>5</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>en</language>
	<article_id_doi></article_id_doi>
	<title_fa>ارزیابی عملکرد رگرسیون خطی چندگانه و انواع مدل خطی تعمیم یافته در تخمین سن یائسگی طبیعی: یک مطالعه توصیفی</title_fa>
	<title>Evaluation of multiple linear regression function and generalized linear model types in estimating natural menopausal age: A cross-sectional study</title>
	<subject_fa></subject_fa>
	<subject>Fertility &amp; Infertility</subject>
	<content_type_fa>Original Article</content_type_fa>
	<content_type>Original Article</content_type>
	<abstract_fa>&lt;div style=&quot;text-align: justify;&quot;&gt;&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;text-justify:inter-ideograph&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;مقدمه: &lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;از آنجا که زنان حدود یک سوم از عمر خود را در یائسگی سپری می&amp;shy;کنند، پیش&amp;shy;بینی صحیح سن یائسگی طبیعی و پارامترهای موثر بر آن، برای افزایش امید به زندگی زنان بسیار مهم است.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;text-justify:inter-ideograph&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;هدف: &lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;هدف از این مطالعه مقایسه عملکرد مدل&amp;shy;های خطی تعمیم&amp;shy;یافته (&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;GLM&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;) و روش حداقل مربعات معمولی (&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;OLS&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;) در پیش&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Arial&amp;quot;,&amp;quot;sans-serif&amp;quot;&quot;&gt;&amp;shy;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;بینی سن یائسگی طبیعی در جمعیت بزرگی از زنان ایرانی بود.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;text-justify:inter-ideograph&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;مواد و روش&amp;shy;ها: &lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;این مطالعه مقطعی با استفاده از داده&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Arial&amp;quot;,&amp;quot;sans-serif&amp;quot;&quot;&gt;&amp;shy;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;های مرحله اول مطالعه&amp;shy;ی کوهورت شاهدیه که در سال 2016-2015 جمع&amp;shy;آوری شده بود، انجام شده است. در مجموع 1251 زن که تجربه یائسگی طبیعی داشتند، وارد مطالعه شدند. برای مدل&amp;shy;سازی سن یائسگی طبیعی، از مدل رگرسیون خطی چندگانه با استفاده از روش &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;OLS&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;و &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;GLMs&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;استفاده شد. با کمک معیار اطلاعات آکائیکه (&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;ACI&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;)، جذر میانگین مربع خطا (&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;RMSE&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;) و میانگین خطای مطلق (&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;MAE&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;)، عملکرد مدل&amp;shy;های رگرسیون اندازه&amp;shy;گیری شد.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;text-justify:inter-ideograph&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;نتایج: &lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;میانگین سن یائسگی زنان 7/4 &lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt; 1/49 سال (3/49&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Sakkal Majalla&amp;quot;&quot;&gt;-&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;8/48 &lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;=&lt;/span&gt; &amp;nbsp;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;CI&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;:95%) با میانه 50 سال بود. تجزیه و تحلیل، مقادیر مشابه معیار &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;Akaike&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;را برای مدل خطی چندگانه با روش &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;OLS&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;و &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;GLM&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;با خانواده &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;Gaussian&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;نشان داد. با این حال، مقادیر &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;RMSE&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;و &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;MAE&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;در مدل &amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;GLM&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;بسیار کمتر بود. در همه &amp;nbsp;&amp;nbsp;&amp;nbsp;مدل&amp;shy;ها، تحصیلات، سابقه جراحی سالپینژکتومی، دیابت، ایسکمیک قلبی و افسردگی به طور معنی&amp;shy;داری با سن یائسگی ارتباط داشتند. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;text-justify:inter-ideograph&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;نتیجه &amp;shy;گیری:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;به منظور پیش&amp;shy;بینی سن یائسگی طبیعی در این مطالعه، &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;GLM&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;با خانواده گاوسی و تابع پیوند &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;Log&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;با کاهش خطاهای &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;RMSE&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;و &lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:10.0pt&quot;&gt;MAE&lt;/span&gt; &lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;می&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Arial&amp;quot;,&amp;quot;sans-serif&amp;quot;&quot;&gt;&amp;shy;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;B Mitra&amp;quot;&quot;&gt;تواند جایگزین مناسبی برای مدل&amp;shy;سازی سن یائسگی طبیعی باشد.&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-family:&amp;quot;B Nazanin&amp;quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&amp;nbsp;&lt;/div&gt;</abstract_fa>
	<abstract>&lt;div style=&quot;text-align: justify;&quot;&gt;&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;font-family:Calibri,&amp;quot;sans-serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Background:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; Since women spend about one-third of their lifespan in menopause, accurate prediction of the age of natural menopause and its effective parameters are crucial to increase women&amp;#39;s life expectancy.&lt;b&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;font-family:Calibri,&amp;quot;sans-serif&amp;quot;&quot;&gt;&lt;a name=&quot;_Hlk80516171&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Objective:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/a&gt; &lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;This study aimed to compare the performance of&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; &lt;a name=&quot;_Hlk52987519&quot;&gt;generalized linear model&lt;/a&gt;s (GLM)&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; and the &lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;ordinary least squares &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;(OLS) method in predicting the age of natural menopause in a large population of Iranian women. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;font-family:Calibri,&amp;quot;sans-serif&amp;quot;&quot;&gt;&lt;a name=&quot;_Hlk80516258&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Materials and Methods:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/a&gt; &lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;This cross-sectional study was conducted using data from the recruitment phase of the &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Shahedieh Cohort Study, Yazd, Iran&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;. In total, 1251 women who had the experience of natural menopause were included. For modeling natural menopause, the multiple linear regression model was employed using the &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;ordinary least squares &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;method and GLMs. With the help of the Akaike information criterion, root-mean-square error (RMSE), and mean absolute error, the performance of regression models was measured.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;font-family:Calibri,&amp;quot;sans-serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Results:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; The mean age of menopausal women was 49.1 &amp;plusmn; 4.7 yr (95% CI: 48.8-49.3) with a median of 50 yr. The analysis showed similar Akaike criterion values for the multiple linear models with the OLS technique and the GLM with the Gaussian family. However, the &lt;a name=&quot;_Hlk39523288&quot;&gt;RMSE &lt;/a&gt;and mean absolute error values were much lower in GLM. In all the models, education, history of salpingectomy, diabetes, &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;a name=&quot;_Hlk53566882&quot;&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;cardiac ischemic&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;, and depression were significantly associated with menopausal age.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;font-family:Calibri,&amp;quot;sans-serif&amp;quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;Conclusion:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; To predict the &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt;age of natural menopause&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span style=&quot;background:white&quot;&gt;&lt;span style=&quot;font-family:&amp;quot;Times New Roman&amp;quot;,&amp;quot;serif&amp;quot;&quot;&gt; in this study, the GLM with the Gaussian family and the log link function with reduced RMSE and mean absolute error can be a good alternative for modeling menopausal age.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;</abstract>
	<keyword_fa>سن یائسگی, مدل­های تعمیم­یافته خطی, کوهورت شاهدیه.</keyword_fa>
	<keyword>Menopause, Etiology, Statistics, Numerical data.</keyword>
	<start_page>377</start_page>
	<end_page>388</end_page>
	<web_url>http://ijrm.ir/browse.php?a_code=A-10-471-1&amp;slc_lang=en&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Nasrin</first_name>
	<middle_name></middle_name>
	<last_name>Sadeghi</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>Sadeghi.stat89@ gmail.com</email>
	<code></code>
	<orcid>0000-0001-5721-3662</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Statistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Sadeghi.stat89@ gmail.com (+98)09387786951</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Hossien</first_name>
	<middle_name></middle_name>
	<last_name>Fallahzadeh</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>Fallahzadeh.ho@gmail.com</email>
	<code></code>
	<orcid>0000-0001-6518-366x</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Research Center of Prevention and Epidemiology of Non-Communicable Diseases,  School of Public Health,  Shahid Sadoughi University of Medical Sciences, Yazd-Iran. Fallahzadeh.ho@gmail.com (+98)09131529486</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Maryam</first_name>
	<middle_name></middle_name>
	<last_name>Dafei</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>maryam_dafei@yahoo.com</email>
	<code></code>
	<orcid>0000-0001-9509-6719</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Research Center for Nursing and Midwifery Care, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences Yazd-Iran. maryam_dafei@yahoo.com (+98)09132588499</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Maryam</first_name>
	<middle_name></middle_name>
	<last_name>Sadeghi</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>Sadeghi.maryam@mail.um.ac.ir</email>
	<code></code>
	<orcid>0000-0002-4337-8770</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Ferdowsi University of Mashhad, Faculty of Mathematical Sciences, Mashhad, Iran. Sadeghi.maryam@mail.um.ac.ir (+98)09378099979</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Masoud</first_name>
	<middle_name></middle_name>
	<last_name>Mirzaei</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>Masoud_mirzaei@hotmail.com</email>
	<code></code>
	<orcid>0000-0001-6455-0747</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of public health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Masoud_mirzaei@hotmail.com (+98) 09134509917</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
