en بررسی ارتباط بین شاخص تغذیه سالم و پارامترهای اسپرمی در مردان نابارور: یک مطالعه مقطعی Fertility & Infertility Original Article Original Article <div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">ناباروری یکی از مشکلات اصلی زوج</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">های جوان در سال</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">های اخیر بوده است. یکی از راه</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">های سنجش کیفیت رژیم غذایی، شاخص تغذیه سالم است که می</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">تواند با ناباروری مرتبط باشد.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف از این مطالعه دستیابی به ارتباط نمره شاخص تغذیه سالم بر پارامترهای مایع منی در مردان نابارور ایرانی است.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مواد و روش&shy; ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">260 مرد واجد شرایط (55-18 سال) که در سال 2018 به کلینیک ناباروری در اصفهان مراجعه کرده بودند، وارد مطالعه شدند. ارزیابی پارامترهای اسپرمی بر اساس ویرایش پنجم راهنمای آزمایشگاهی </span></span><span dir="LTR" style="font-size:10.0pt">WHO</span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">انجام و از یک پرسشنامه 168 آیتمی غذایی برای تعیین میزان دریافت رژیم غذایی شرکت</span></span><span dir="LTR" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">کنندگان استفاده شد. امتیاز کل شاخص تغذیه سالم با جمع کردن نمرات هر 13 مؤلفه بر اساس مؤلفه‌های </span></span><span dir="LTR" style="font-size:10.0pt">HEI-2015</span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">و استانداردهای امتیازدهی محاسبه شد.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">در مدل خام هیچ تفاوت معنی</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داری بین ترتایل سوم شاخص تغذیه سالم و میانگین پارامترهای اسپرمی در مقایسه با ترتایل اول وجود نداشت. همچنین ارتباط معنی</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داری بین پارامترهای اسپرمی و امتیاز شاخص تغذیه سالم در مدل خام و تعدیل شده برای متغیرهای مخدوش</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">گر به جز غلظت اسپرم مشاهده نشد (04/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">، 99/0 ،15/0 </span></span><span lang="FA" style="font-size:10.0pt">:</span><span dir="LTR" style="font-size:10.0pt">CI</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">، و 39/0 </span></span><span lang="FA" style="font-size:10.0pt">:</span><span dir="LTR" style="font-size:10.0pt">OR</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">). میان افراد در بالاترین ترتایل شاخص تغذیه سالم خطر داشتن اسپرم با غلظت و تحرک غیرنرمال کمتر بود و در مدل تعدیل شده خطر داشتن اسپرم با غلظت غیرنرمال کاهش یافت و ریسک تحرک غیرنرمال افزایش یافت.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجه &shy;گیری:</span></span></b> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">در این مطالعه مقطعی، رابطه معنی</span></span><span lang="FA" style="font-size:11.0pt"><span cambria="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داری بین امتیاز شاخص تغذیه سالم و پارامترهای اسپرمی به جز غلظت مشاهده نشد، از این رو بهتر است مطالعات بیشتری در این زمینه صورت گیرد.</span></span></span></span></span></span></span><br> <br> &nbsp;</div> <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Background:</span></b><span style="font-size:12.0pt"> Infertility has been a major problem for young couples in recent years. One way to assay the diet quality is the healthy eating index (HEI), related to infertility.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Objective:</span></b><span style="font-size:12.0pt"> This study aims to assess the association between the HEI score with semen parameters in Iranian infertile men.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Materials and Methods:</span></b><span style="font-size:12.0pt"> 260 eligible men (18-55 yr), were referred to the major infertility clinic in the summer of 2018 and entered this cross-sectional study. </span><span style="font-size:12.0pt">Based on the 5^th edition of the world health organization laboratory manual,</span><span style="font-size:12.0pt"> semen parameters including: sperm concentration, volume, motility, and morphology were analyzed</span><span style="font-size:12.0pt"> and to specify dietary intake of individuals a 168-item questionnaire was used</span><span style="font-size:12.0pt">. Also, to calculate the total HEI score, all 13 components based on HEI-2015 components and scoring standards were summed up.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Results:</span></b><span style="font-size:12.0pt"> Participants in the highest tertile, had no difference in mean sperm parameters with those in the lowest tertile in the crude model. No significant association was found between sperm parameters and HEI score tertiles in the crude model, even after adjustment for potential confounders, except for concentration (OR: 0.39 and CI: 0.15, 0.99, p = 0.04). Participants in the highest tertile had a lower risk of abnormal concentration and motility in the crude model. The risk of abnormal concentration decreased, and motility increased in the adjusted model.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Conclusion:</span></b><span style="font-size:12.0pt"> In this cross-sectional study, there was no significant relationship between HEI and sperm indexes, except for sperm concentration. Therefore, more studies need to be done in future.</span></span></span></span></div> رژیم غذایی, سالم, آنالیز مایع منی, ناباروری, مطالعات مقطعی. Diet, Healthy, Semen analysis, Infertility, Cross-sectional studies. 931 940 http://ijrm.ir/browse.php?a_code=A-10-1837-2&slc_lang=en&sid=1 Kimia Leilami Leilamikimia@gmail.com 0000-0002-2023-300X No Nutrition Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Azadeh Zarei a_z.zarei@yahoo.com 0000-0003-0343-4691 No Students’ Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Mehran Nouri mehran_nouri71@yahoo.com 0000-0002-7031-3542 No Students’ Research Committee, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran. Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Milad Bagheri milad.bagheri75@gmail.com 0000-0003-0979-3337 No Students’ Research Committee, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran. Mahsa Shirani mahsa.shirani1373@yahoo.com 0000-0002-6630-7473 Yes Students’ Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.