International Journal of Reproductive BioMedicine
International Journal of Reproductive BioMedicine
IJRM
Medical Sciences
http://ijrm.ir
1
admin
2476-4108
2476-3772
10.29252/ijrm
en
jalali
1401
11
1
gregorian
2023
2
1
21
2
online
1
fulltext
en
تأثیر همه گیری کووید-19 بر سلامت مادر و نوزاد: یک مطالعه کوهورت از اصفهان، ایران
The effect of Coronavirus disease pandemic on maternal and neonatal health: A cohort study from Isfahan, Iran
Pregnancy Health
Original Article
Original Article
<div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مقدمه: </span></span></b> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">بیماری همه­گیر کروناویروس 2019</span></span> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">(</span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">) ممکن است تأثیر زیادی بر سلامت مادران و نوزادان در سراسر جهان داشته باشد، با این حال، مطالعات کمی این موضوع را بررسی کرده­اند</span></span>.</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">این مطالعه با هدف بررسی تأثیر همه­گیری کووید-19 بر سلامت مادر و نوزاد انجام شد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مواد و روش ­ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">این مطالعه همگروهی گذشتهنگر به تجزیه و تحلیل دادههای جمعآوریشده از فروردین تا اردیبهشت 1399 و مدت مشابه سال 1398 بر روی 5711 زن باردار مراجعهکننده به مراکز جامع سلامت و مراکز بهداشتی درمانی استان اصفهان پرداخت. زنان باردار و نوزادان تا 40 روز پس از زایمان پیگیری شدند. خصوصیات دموگرافیک، متغیرهای مربوط به قبل از بارداری، مراقبت های دوران بارداری و متغیرهای بعد از بارداری جمع آوری شد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">در مجموع 5711 زن باردار مورد مطالعه قرار گرفتند که از این تعداد (61%) 3477 در سال 2021 (قبل از همهگیری کووید-19) و (39%) 2234 در طول همهگیری کووید-19 در سال 2022 مراجعه کردند. برای کسانی که در شهرها با جمعیت بیش از 20000 نفر زندگی میکنند، تعداد مراقبت قبل از بارداری نسبت به قبل از همه­گیری 2% کمتر بود، در حالی که برای افرادی که در مناطق روستایی و شهرهای با جمعیت کمتر از 20000 نفر زندگی می­کنند، حدود 2% بیشتر شده بود که تفاوت مشاهده شده از نظر آماری معنی­دار بود (005/0 =</span></span><span dir="LTR" style="font-size:10.0pt">p</span> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">). تعداد مادران دارای سابقه بیماری زمینه­ای که در طول همه­گیری کووید-19 (47%) به یک مرکز جامع مراقبت­های بهداشتی مراجعه کرده­اند نسبت به قبل از همه­گیری (41%) 6% کمتر شده بود. شیوع پرفشاری خون و دیابت بارداری مادران در زمان کرونا به ترتیب 5% (109 نفر) و 20% (445 نفر) مشاهده گردید، که نسبت به دوره قبل به ترتیب 2% و 4% </span></span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">بیشتر است که از نظر آماری معنی­دار می­باشد. کرونا تأثیر معنی­داری بر سایر ویژگی­های مربوط به مادران و نوزادان نداشته و تفاوت معنی­داری قبل و حین پاندمی کرونا مشاهده نگردید.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتیجه­ گیری:</span></span></b> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">همه­گیری کووید-19 در مقایسه با گروهی که در معرض آن قرار نگرفته بودند، تأثیر قابل توجهی بر سلامت مادران و نوزادان نداشت.</span></span><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></span></span></span></span></span><br>
</div>
<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">Background: </span></span></b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">The Coronavirus disease-2019 (COVID-19) pandemic may profoundly impact on maternal and neonatal health worldwide. However, a few studies have investigated this topic.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">Objective:</span></span></b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> This study aimed to investigate the impact of the </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19 </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">pandemic on maternal and neonatal health.</span></span><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""></span></span></b></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">Materials and Methods: </span></span></b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">This </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">retrospective cohort </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">study analyzed collected data from </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">March to May 2020, and the same period in 2019, involving </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">5711 </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">pregnant women referring to </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">comprehensive healthcare centers in Isfahan province health facilities,</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> Iran. Pregnant w</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">omen and neonates were followed-up until 40 days after the delivery. Demographic characteristics, pre-pregnancy, antenatal care, and post-pregnancy variables were collected.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">Results: </span></span></b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">A total of 5711 pregnant women were studied, of whom 3477 (61%) were referred in 2019 (before the </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> pandemic as nonexposed) and 2234 (39%) during the </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19 </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">pandemic (as exposed group) in 2020. For those living in cities with a population of > 20,000, the number of </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">antenatal care were</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> lower about 2% compared to nonexposed group (p = 0.01). The number of mothers with a history of the underlying disease who referred to a comprehensive healthcare center during the </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19 </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">pandemic (47%) was lower about 6% compared to nonexposed group (41%) (p < 0.001). During the </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> pandemic, the prevalence of hypertension and gestational diabetes mellitus was 5% (n = 109) and 20% (n = 445), which were higher about 2% and 4%, respectively, compared to nonexposed group. The </span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">COVID-19</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""> pandemic had no other significant effect on mothers' and neonates' other characteristics than nonexposed group. </span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">Conclusion: </span></span></b><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif"">The COVID-19 pandemic imposes no significant effect on mothers' and neonates' health compared to nonexposed group.</span></span></span></span></span></div>
سلامت مادر, سلامت نوزادان, بارداری, کووید-19.
Maternal health, Neonatal health, Pregnancy, COVID-19.
159
166
http://ijrm.ir/browse.php?a_code=A-10-2245-1&slc_lang=en&sid=1
Hourieh
Ansari
houri_ansari@yahoo.com