International Journal of Reproductive BioMedicine
International Journal of Reproductive BioMedicine
IJRM
Medical Sciences
http://ijrm.ir
1
admin
2476-4108
2476-3772
10.29252/ijrm
en
jalali
1402
5
1
gregorian
2023
8
1
21
8
online
1
fulltext
en
بررسی ویروس COVID-19 در مایع واژن و خون قاعدگی و تأثیر آن بر طول دوره قاعدگی و میل جنسی: یک مطالعه مقطعی
Investigation of Coronavirus disease 2019 virus in vaginal fluid and menses blood and the effect on menstrual cycle duration and sexual desire: A cross-sectional study
Reproductive Biology
Original Article
Original Article
<div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">بیماری کروناویروس-2019 (</span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">) در گلو، ادرار و مدفوع شناسایی شده است اما شواهد کمی از انتقال جنسی آن گزارش شده است.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">هدف این مطالعه تشخیص وجود </span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> در مایعات واژن و خون قاعدگی بود. مدت چرخه قاعدگی و شدت میل جنسی از دیگر اهداف بود.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مواد و روش ­ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">در این مطالعه مقطعی، 300 نفر با تأییدیه بالینی ابتلا به عفونت </span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">که به بیمارستان الزهرا (س) دانشگاه علوم پزشکی تبریز مراجعه کرده بودند، به دو دسته بیماران با علایم خفیف (178 نفر، فشار نسبی اکسیژن 91 </span></span><span lang="FA" style="font-size:10.0pt">≤</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> (</span></span><span dir="LTR" style="font-size:10.0pt">PO2</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">)) و گروه با علایم شدید (122 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">n</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">، 91 </span></span><span lang="FA" style="font-size:10.0pt">≥ </span><span dir="LTR" style="font-size:10.0pt">PO2</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">) نیز بر اساس علائم بالینی و بستری در بیمارستان، از ژانویه تا می 2021، تقسیم شدند. مشخصات دموگرافیک، قاعدگی و میل جنسی افراد در پرسشنامه ثبت شد. خونگیری در روزهای 4-2 قاعدگی و نمونه­گیری مایع واژینال در زمان پایان قاعدگی با استفاده از سواب نوک داکرون برای </span></span><span dir="LTR" style="font-size:10.0pt">PCR</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> انجام شد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">شرکتکنندگان در گروههای خفیف (میانگین سنی: 41/7 </span></span><span lang="FA" style="font-size:10.0pt">±</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> 32/43) و شدید (میانگین سنی: 9/6 </span></span><span lang="FA" style="font-size:10.0pt">±</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> 15/47 سال) مورد مطالعه قرار گرفتند. عفونت </span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> منجر به کوتاه شدن مدت چرخه قاعدگی در گروه شدید شد (9/2 </span></span><span lang="FA" style="font-size:10.0pt">±</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> 15/30 روز در مقابل 1/2 </span></span><span lang="FA" style="font-size:10.0pt">±</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> 12/25 روز، 01/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">). آزمایش </span></span><span dir="LTR" style="font-size:10.0pt">PCR</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> برای مایع واژن و خون قاعدگی برای همه موارد منفی بود. میل جنسی در هر دو گروه به طور قابل توجهی کاهش یافت.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتیجه­ گیری: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">این ویروس در خون قاعدگی و مایع واژن زنان مبتلا به عفونت کووید-19 وجود ندارد که خطر انتقال ویروس از طریق مجاری واژن را کم می</span></span><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif"">­</span></span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">کند. عفونت شدید </span></span><span dir="LTR" style="font-size:10.0pt">COVID-19</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> ممکن است بر مدت قاعدگی تأثیرگذار باشد.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span></div>
<div style="text-align: justify;"><span style="font-size:12pt"><span style="font-family:"Times New Roman","serif""><b>Background:</b> Coronavirus disease 2019 (COVID-19) was detected in the throat, urine, and feces but has little evidence documented of sexual transmission. </span></span><br>
<span style="font-size:12pt"><span style="font-family:"Times New Roman","serif""><b>Objective:</b> Here, we aimed to diagnose the presence of COVID-19 in vaginal fluids and menses blood. Menstrual cycle duration and sexual desire were the other aims. </span></span><br>
<span style="font-size:12pt"><span style="font-family:"Times New Roman","serif""><b>Materials and Methods:</b> In this cross-sectional study, 300 individuals with clinical approval of COVID-19 infection who were referred to the Alzahra hospital of Tabriz University of Medical Sciences, Tabriz, Iran were divided into mild (n = 178, partial pressure of oxygen ≥ 91) and severe (n = 122, partial pressure of oxygen ≤ 91) groups, also based on clinical signs and hospitalization, from January to May 2021. Demographic characteristics, menstruation, and sexual desire of individuals were recorded in the questionnaire blood sampling was done on days 2-4 for menses, and vaginal fluid after menses for polymerase chain reaction by using a Dacron tip swab.</span></span><br>
<span style="font-size:12pt"><span style="font-family:"Times New Roman","serif""><b>Results:</b> Participants were studied in the mild (mean age: 43.32 ± 7.41) and severe (mean age: 47.15 ± 6.9) groups. COVID-19 infection resulted in shortening the menstrual cycle duration in the severe group (30.15 ± 2.9 vs. 25.12 ± 2.1 days, p = 0.01). Polymerase chain reaction test for vaginal fluid and menses blood was negative for all cases. Sexual desire declined in both groups, significantly.</span></span><br>
<span style="font-size:12pt"><span style="font-family:"Times New Roman","serif""><b>Conclusion:</b> This virus was not present in the menses blood and vaginal fluid of women with COVID-19 infection, which proposed a low risk of virus transmission via vaginal tracts. Severe COVID-19 infection may affect the menstrual duration.</span></span></div>
کرونا ویروس, کووید-۱۹, واژن, قاعدگی.
Coronavirus, COVID-19, Vagina, Menstruation.
639
646
http://ijrm.ir/browse.php?a_code=A-10-2255-2&slc_lang=en&sid=1
Leila
Sadeghi
la.sadeghi2013.ls@gmail.com