en داپلر شریان رحم و جریان خون آندومتر در انتقال جنین منجمد: یک مطالعه مشاهده‌ای Fertility & Infertility Original Article Original Article <div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">میزان لانه &shy;گزینی پس از فناوری کمک باروری (</span></span><span dir="LTR" style="font-size:10.0pt">ART</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">)</span></span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">به دو عامل مهم بستگی دارد: جنین با کیفیت خوب و پذیرش آندومتر. پذیرش آندومتر عمدتاً با اندازه</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">گیری اولتراسوند ضخامت و مورفولوژی آندومتر ارزیابی می</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">شود.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">این مطالعه با هدف بررسی رابطه بین شاخص&shy;های داپلر شریان رحمی / پرفیوژن آندومتر و میزان بارداری انجام شد.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مواد و روش&shy; ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">این مطالعه مشاهده‌ای آینده‌نگر بر روی 250 زن کاندید انتقال جنین در چرخه انتقال جنین منجمد از ژانویه 2022 تا ژولای 2022 انجام شد. برای ارزیابی پذیرش آندومتر، سونوگرافی داپلر رحم قبل از جنین انجام شد. انتقال با آندومتر با ظاهر مطلوب (ضخامت آندومتر بیشتر یا مساوی 7 میلی</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">متر و خط سه&shy;گانه. علاوه بر این، بیماران بر اساس حاملگی بالینی به دو گروه مثبت و منفی تقسیم شدند و شاخص&shy;های شریان رحمی و پرفیوژن آندومتر بین این گروه&shy;ها مقایسه شد).</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داپلر شریان رحمی نشان داد که شاخص ضربان بین دو گروه مثبت و منفی حاملگی بالینی تفاوت معنی‌داری دارد، اما شاخص مقاومت و حداکثر سرعت سیستولیک از نظر آماری تفاوت معنی‌داری با هم ندارند. همچنین پرفیوژن آندومتر بین دو گروه حاملگی بالینی تفاوت معنی</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داری داشت. پرفیوژن آندومتر در &nbsp;&nbsp;&nbsp;گروه</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">های حاملگی بالینی مثبت به طور معنی</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">داری بهتر بود.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجه&shy; گیری:</span></span></b> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">سونوگرافی داپلر ابزاری مفید برای ارزیابی پذیرش آندومتر است.</span></span><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></span></span></span></span></span><br> &nbsp;</div> <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Background:</span></b><span style="font-size:12.0pt"> The implantation rate after assisted reproductive technology depends on 2 important factors, good quality embryo and endometrial receptivity. Endometrial receptivity is mainly assessed by ultrasound measurement of endometrial thickness and morphology.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Objective:</span></b><span style="font-size:12.0pt"> This study aimed to investigate the relationship between uterine artery Doppler indices/endometrial perfusion and pregnancy rate.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Materials and Methods:</span></b><span style="font-size:12.0pt"> This cohort study was done on 250 women who were candidates for frozen embryo transfer from January to July 2022. For assessing endometrial receptivity, we performed a Doppler ultrasound of the uterus before embryo transfer with apparently desirable endometrium (endometrial thickness &ge; 7 mm and 3 line endometrial pattern). In addition, the women were divided into 2 groups according to assisted reproductive technology outcome (clinical pregnancy), group I positive clinical pregnancy, and group II negative clinical pregnancy, and uterine artery indices and endometrial perfusion were compared between these groups.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Results:</span></b><span style="font-size:12.0pt"> Uterine artery Doppler showed that the pulsatility index was significantly different between positive and negative clinical pregnancy groups, but resistance index and peak systolic velocity (PSV) did not have statistically significant differences. Also, endometrial perfusion was significantly different between the 2 groups of clinical pregnancy. Endometrial perfusion was significantly better in positive clinical pregnancy groups. </span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><b><span style="font-size:12.0pt">Conclusion:</span></b><span style="font-size:12.0pt"> Doppler ultrasound can help to assess endometrial receptivity.</span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><span style="font-size:10.0pt"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></div> داپلر, انتقال جنین, فناوری کمک باروری, بارداری. Doppler ultrasonography, Embryo transfer, Assisted reproductive technology, Pregnancy. 205 212 http://ijrm.ir/browse.php?a_code=A-10-226-8&slc_lang=en&sid=1 Fereshteh Bahrami fereshtehbahrami1966@gmail.com 0000-0002-8663-7234 No Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Maryam Eftekhar eftekharmaryam@yahoo.com 0000-0003-3835-5635 Yes Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Leila Zanbagh javadkhataie@gmail.com 0000-0002-0892-2662 No Department of Obstetrics and Gynecology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.