en ویژگی های سیر کووید-19 شدید و بحرانی در زنان باردار: یک مطالعه مقطعی آینده نگر Pregnancy Health Original Article Original Article <div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">با شروع همه&shy;گیری بیماری کرونا ویروس 2019 (کووید-19)، مطالعات نشان داد که خطر ابتلا به نوع شدید این بیماری در زنان باردار بیشتر می&shy;باشد.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">این مطالعه به بررسی ویژگی‌های انواع شدید و بسیار شدید عفونت کووید-19 در زنان باردار می‌پردازد.</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مواد و روش&shy; ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">در این مطالعه مقطعی آینده‌نگر، سوابق پزشکی 120 زن باردار مبتلا به کووید-19 شدید و بسیار شدید با هم مقایسه شد. این زنان در مرکز بیماری‌های عفونی، شیمکنت، قزاقستان از دسامبر 2021 تا مه 2022 تحت درمان قرار گرفته بودند. عواملی مانند زمان بستری در بیمارستان، مدت دوره بستری، بیماری</span></span><span dir="LTR" style="font-size:11.0pt"><span arial="" style="font-family:">&shy;</span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">های همراه با حاملگی مادر، سن، عوارض بارداری و پس از زایمان، پیامدهای بارداری و نوع درمان مورد تجزیه و تحلیل قرار گرفت.</span></span><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">87 زن باردار (5/%72) مبتلا به کووید-19 شدید و 33 نفر (5/%27) با نوع بسیار شدید کووید-19 وارد مطالعه شدند. داده&shy;های زیر هنگام مقایسه تعداد حاملگی، بسته به سن حاملگی به دست آمد: در هفته&shy;های 12-1، این شاخص 95/0</span></span><span lang="FA" style="font-size:10.0pt"> &plusmn; </span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">75/3 بود. در هفته&shy;های 27-13 شاخص 00/3 (00/00-4/2 </span></span><span lang="FA" style="font-size:10.0pt">:</span><span dir="LTR" style="font-size:10.0pt">Q1-Q3</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">)، در هفته&shy;های 40-28 شاخص 00/3 (00/4-00/2 </span></span><span lang="FA" style="font-size:10.0pt">:</span><span dir="LTR" style="font-size:10.0pt">Q1-Q3</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">). نتایج نشاندهنده این بود که عفونت شدید کووید-19 در زنان با بارداری سوم رخ می&shy;دهد&nbsp;&nbsp;&nbsp; &nbsp;(00/4-00/2 </span></span><span lang="FA" style="font-size:10.0pt">:</span><span dir="LTR" style="font-size:10.0pt">Q1-Q3</span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">)</span></span><span dir="LTR" style="font-size:10.0pt">Me 3.00</span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">).</span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجه &shy;گیری: </span></span></b><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">خطر پیشرفت بیماری به کووید-19 شدید و بسیار شدید در زنان باردار بالای 33 سال و در هفته‌های 40-28 بارداری وجود دارد. ارجاع زودهنگام به پزشک در بیمارستان، بستری شدن به موقع و شروع درمان، خطر تشدید وضعیت بیمار و ایجاد عوارض وحشتناک را کاهش می&shy;دهد.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span></div> <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Background:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> At the beginning of the Coronavirus disease 2019 (COVID-19) pandemic, studies showed that the risk of severe disease was higher in pregnant women.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Objective:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> This study investigates the characteristics of severe and critical types of COVID-19 coronavirus infection in pregnant women.</span></span></span></span></span><br> <span style="font-size:10pt"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Materials and Methods:</span></span></b> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">This</span></span> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">prospective cross-sectional study compared the medical records of 120 pregnant women with severe and very severe COVID-19 treated at the Infectious Disease Center, Shymkent, Kazakhstan from December 2021 to May 2022. Factors such as time of hospital admission, hospitalization period, maternal comorbidities, age, pregnancy and postpartum complications, pregnancy outcomes, and treatment type were analyzed. </span></span></span></span><br> <span style="font-size:10pt"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Results: </span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">87 (72.5%) pregnant women with severe and 33 (27.5%) with </span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">critical</span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> type of COVID-19 were included. The following data were obtained when comparing the pregnancy</span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> parity of the subjects, depending on the gestational age: in 1-12 wk, the indicator was 3.75 &plusmn; 0.95; in 13-27 wk 3.00 (Q1-Q3: 2.00-4.00), in 28-40 wk 3.00 (Q1-Q3: 2.00-4.00). Severe COVID-19 coronavirus infection occurs in women with more than a third pregnancy (Me 3.00 [Q1-Q3: 2.00-4.00]).</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> There is a risk of disease progression to severe and critical COVID-19 in pregnant women older than 33 yr of age and at 28-40 wk gestation. Early referral to a doctor in hospital, timely hospitalization, and initiated treatment reduces the risk of aggravation of the patient&#39;s condition and development of formidable complications. </span></span></span></span></span></div> کووید-19, بارداری, عفونت. COVID-19, Pregnancy, Infection. 229 234 http://ijrm.ir/browse.php?a_code=A-10-2414-1&slc_lang=en&sid=1 Gulbanu Ganikyzy Shaimerdenova gulbanu1008@mail.ru 0000-0002-5656-0918 Yes South Kazakhstan Medical Academy, Shymkent, Kazakhstan. Gulzhan Narkenovna Abuova dr.abuova@gmail.com 0000-0002-1210-2018 No South Kazakhstan Medical Academy, Shymkent, Kazakhstan. Saltanat Nalibekkyzy Kulbayeva saltanatkulbayeva@gmail.com 0000-0003-1032-3877 No South Kazakhstan Medical Academy, Shymkent, Kazakhstan.