International Journal of Reproductive BioMedicine
International Journal of Reproductive BioMedicine
IJRM
Medical Sciences
http://ijrm.ir
1
admin
2476-4108
2476-3772
10.29252/ijrm
en
jalali
1403
7
1
gregorian
2024
10
1
22
10
online
1
fulltext
en
پیامدهای مادری و نوزادی در زنان مبتلا به بیماری کووید-19 : یک مطالعه کوهورت گذشتهنگر
Maternal and neonatal outcomes in women with COVID-19: A retrospective cohort study
Pregnancy Health
Original Article
Original Article
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مقدمه: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">با توجه به شواهد متناقضی که در مورد تأثیر بیماری کووید- 19 بر پیامدهای بارداری و نوزادی وجود دارد. انجام این تحقیق در سال اول کرونا در شمال ایران که یک مکان پربازدید و شلوغ می­باشد ضروری است چون که احتمال ابتلا به ویروس کرونا و شدت عفونت افزایش می­یابد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">هدف:</span></span></b> <span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مطالعه حاضر با هدف بررسی و مقایسه پیامدهای بارداری و نوزادی در زنان باردار مبتلا و غیرمبتلا به بیماری کووید-19 در بارداری انجام شد.</span></span><b><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif""></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">مواد و روش­ ها: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">در این مطالعه همگروهی گذشته­نگر، اطلاعات 160 زن باردار مراجعه­کننده به 3 بیمارستان مازندران از فروردین تا اسفند 1399 با استفاده از چک لیست از پرونده پزشکی آنها استخراج شد. شرکت­کنندگان به 2 گروه تقسیم شدند. (گروه الف: 80 زن باردار مبتلا به کووید-19، گروه ب: 80 زن باردار غیرمبتلا). کلیه اطلاعات مربوط به پیامدهای مادری و نوزادی از پرونده دو گروه استخراج و مقایسه شد</span></span><span dir="LTR" style="font-size:11.0pt"><span style="font-family:"Arial","sans-serif"">.</span></span><span style="font-size:11.0pt"><span style="font-family:"B Mitra""> نتایج بهدستآمده از مقایسه 2 گروه از زنان باردار از نتیجه آزمون </span></span><span dir="LTR" style="font-size:10.0pt">RT-PCR</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""> واکنش زنجیرهای پلیمراز رونویسی معکوس مورد تجزیه و تحلیل قرار گرفت.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتایج: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">شایع­ترین علامت در گروه کووید-19، تب و سرفه بود. عوارض بارداری مانند سقط (4/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">)، پره­اکلامپسی (45/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">) و زایمان زودرس (45/0 </span></span><span lang="FA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">) در 2 گروه معنی­دار نشد. تفاوت آماری معنی­داری بین 2 گروه در مورد پیامدهای بارداری و نوزادی وجود نداشت.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">نتیجه­ گیری: </span></span></b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra"">علیرغم اوج و شدت بیماری کووید-19 در سال اول همهگیری، به نظر میرسد که آن تأثیری بر پیامدهای مادری و نوزادی در زنان مبتلا نداشت.</span></span></span></span></span></span></span><br>
<div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="font-size:12.0pt">Background: </span></b><span style="font-size:12.0pt">Considering the conflicting evidence that exists regarding the effect of the coronavirus disease 2019 (COVID-19) on pregnancy and newborn outcomes, it is necessary to conduct this research during the first year in the north of Iran, a highly visited and trafficked place, which increases the possibility of contracting the virus and severity of the infection.</span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="font-size:12.0pt">Objective: </span></b><span style="font-size:12.0pt">This study aimed to compare maternal and neonatal outcomes in pregnant women with and without COVID-19. </span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="font-size:12.0pt">Materials and Methods:</span></b><span style="font-size:12.0pt"> In this </span><span style="font-size:12.0pt">retrospective cohort study, data from 160 pregnant women referred to 3 hospitals in Mazandaran, Iran from April 2020 to March 2021 were extracted from their medical records using checklists. Participants were divided into 2 groups: group A) 80 pregnant women with COVID-19, group B) 80 noninfected pregnant women. All information related to maternal and neonatal outcomes were extracted and compared from the files of the 2 groups. The results obtained from comparing 2 groups of pregnant women from the result of the <span style="background:white">reverse-transcription polymerase chain reaction</span> test were analyzed.</span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="font-size:12.0pt">Results:</span></b><span style="font-size:12.0pt"> The most common symptoms in the COVID-19 group were fever and cough. Pregnancy complications such as abortion, pre-eclampsia, and premature birth were not significant between groups (p = 0.4, 0.45, 0.45, respectively). No statistically significant difference was observed between groups regarding maternal and neonatal outcomes.</span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="font-size:12.0pt">Conclusion:</span></b><span style="font-size:12.0pt"> Despite the peak and severity of the COVID-19 disease in the first year of the pandemic, it seems that it had no effect on maternal and neonatal outcomes in each trimester of pregnancy in affected women.</span></span></span></span></span></div>
بارداری, کووید-19, پیامد.
Pregnancy, COVID-19, Outcome.
793
800
http://ijrm.ir/browse.php?a_code=A-10-2571-1&slc_lang=en&sid=1
Malihe
Nourollahpour Shiadeh
malihe.nurollahpur@gmail.com