International Journal of Reproductive BioMedicine
International Journal of Reproductive BioMedicine
IJRM
Medical Sciences
http://ijrm.ir
1
admin
2476-4108
2476-3772
10.29252/ijrm
en
jalali
1403
6
1
gregorian
2024
9
1
22
9
online
1
fulltext
en
ضخامت اینتیما مدیا شریان کاروتید در زنان مبتلا به سندرم تخمدان پلیکیستیک: یک مطالعه مقطعی
Carotid artery intima-media thickness in women with polycystic ovary syndrome: A cross-sectional study
Reproductive Biology
Original Article
Original Article
<div style="text-align: justify;"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مقدمه: </span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">چاقی در سندرم تخمدان پلی­کیستیک (</span></span><span dir="LTR" style="font-size:10.0pt">PCOs</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">) ممکن است خطر ابتلا به بیماری­های قلبی عروقی را افزایش دهد. ضخامت اینتیما مدیا کاروتید (</span></span><span dir="LTR" style="font-size:10.0pt">CIMT</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">) یک نشانگر قابل قبول در ارزیابی خطر بیماری قلبی است.</span></span><b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">هدف:</span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> این مطالعه با هدف ارزیابی </span></span><span dir="LTR" style="font-size:10.0pt">CIMT</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> در زنان مبتلا به </span></span><span dir="LTR" style="font-size:10.0pt">PCOS</span><span style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> در مقایسه با زنان غیر</span></span> <span dir="LTR" style="font-size:10.0pt">PCOS</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">انجام شد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مواد و روش­ ها: </span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">این مطالعه مقطعی بر روی 48 زن مراجعه­کننده به بیمارستان امام رضا (ع) کرمانشاه از تیرماه 1399 تا 1400 انجام شد. زنان به 2 گروه از زنان </span></span><span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">مبتلا به</span></span> <span dir="LTR" style="font-size:10.0pt">PCOS </span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">و غیر</span></span><span dir="LTR" style="font-size:11.0pt">) </span><span dir="LTR" style="font-size:10.0pt">PCOS</span> <span lang="FA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">24 </span></span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نفر/ هر گروه) تقسیم شدند.</span></span> <span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">ضخامت اینتیما مدیا شریان کاروتید شرکت­کنندگان در هر دو طرف در 3 ناحیه اندازه­گیری و میانگین آن ثبت شد.</span></span> <b><span lang="FA" style="font-size:11.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">میانگین ضخامت اینتیما مدیا شریان کاروتید در گروه مورد در محدوده طبیعی بود. اما به طور معنی­داری بیشتر از گروه کنترل بود (17/0 </span></span><span lang="AR-SA" style="font-size:10.0pt">±</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> 71/0 در مقابل 09/0 </span></span><span lang="AR-SA" style="font-size:10.0pt">±</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> 57/0 میلی­متر، 019/0 </span></span><span lang="AR-SA" style="font-size:10.0pt">= </span><span dir="LTR" style="font-size:10.0pt">p</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">).</span></span><b><span dir="LTR" style="font-size:11.0pt"></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجه ­گیری: </span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">با توجه به ضخامت بالاتر </span></span><span dir="LTR" style="font-size:10.0pt">CIMT</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> در زنان مبتلا به </span></span><span dir="LTR" style="font-size:10.0pt">PCOS</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">، میتوان نتیجه گرفت که </span></span><span dir="LTR" style="font-size:10.0pt">PCOS</span><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:"> خطر ابتلا به بیماریهای قلبی را در زنان افزایش میدهد.</span></span><span dir="LTR" style="font-size:11.0pt"></span></span></span></span></span></span></div>
<div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:normal"><span calibri="" light=""><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">Background:</span></span></b> <span style="font-size:12.0pt"><span new="" roman="" times="">Obesity in polycystic ovary syndrome (PCOS) may increase the risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is an acceptable marker in assessing the risk of heart disease.</span></span><span lang="EN" style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:normal"><span calibri="" light=""><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">Objective:</span></span></b> <span style="font-size:12.0pt"><span new="" roman="" times="">This study aimed to evaluate the CIMT in PCOS women compared to non-PCOS women.</span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:normal"><span calibri="" light=""><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">Materials and Methods:</span></span></b> <span style="font-size:12.0pt"><span new="" roman="" times="">This cross-sectional study was conducted on 48 women who referred to Imam Reza hospital, Kermanshah, Iran from </span></span><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">July 2020-2021</span></span><span style="font-size:12.0pt"><span new="" roman="" times="">. Women were divided into 2 groups of PCOS and non-PCOS women (n = 24/each). The intima-media thickness of participants’ carotid artery was measured on both sides in 3 areas, and its mean was recorded.</span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:normal"><span calibri="" light=""><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">Results:</span></span></b> <span style="font-size:12.0pt"><span new="" roman="" times="">The mean thickness of the carotid artery intima-media in the case group was within the normal range; but it was significantly higher than the control group (0.71 ± 0.17 vs. 0.57 ± 0.09 mm, p = 0.019).</span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:normal"><span calibri="" light=""><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" times="">Conclusion:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" times=""> Considering the higher thickness of CIMT in women with PCOS, it can be concluded that PCOS increases the risk of heart diseases in women.</span></span></span></span></span><br>
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<div style="text-align: center;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="line-height:normal"><b><i>This article has been extracted from M.D. Thesis. (Mohammad Reza Ghasempour)</i></b></span><span style="line-height:normal"><span style="color:#26282a"></span></span></span></span></div>
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بیماری تخمدان پلیکیستیک, آترواسکلروزیس, ضخامت اینتیما مدیا, شریان کاروتید, بیماریهای قلبی عروقی
Polycystic ovary disease, Atherosclerosis, Intima media thickness, Carotid artery, Cardiovascular disease.
749
754
http://ijrm.ir/browse.php?a_code=A-10-1101-3&slc_lang=en&sid=1
Nazanin
Farshchian
N_farshchian2000@yahoo.com