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Volume 12, Issue 1 (2-2014)
IJRM 2014, 12(1): 47-56 |
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Alijahan R, Hazrati S, Mirzarahimi M, Pourfarzi F, Ahmadi Hadi P. Prevalence and risk factors associated with preterm birth in Ardabil, Iran. IJRM 2014; 12 (1) :47-56
URL: http://ijrm.ir/article-1-473-en.html
URL: http://ijrm.ir/article-1-473-en.html
Rahele Alijahan1 
, Sadegh Hazrati * 2, Mehrdad Mirzarahimi3 , Farhad Pourfarzi3 , Peymaneh Ahmadi Hadi4
, Sadegh Hazrati * 2, Mehrdad Mirzarahimi3 , Farhad Pourfarzi3 , Peymaneh Ahmadi Hadi4
1- Province Heath Center, Ardabil University of Medical Science, Ardabil, Iran.
2- School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran ,S.hazrati@Arums.ac.ir
3- Department of Community Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
4- District Health Center, Ardabil University of Medical Science, Ardabil, Iran
2- School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran ,
3- Department of Community Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
4- District Health Center, Ardabil University of Medical Science, Ardabil, Iran
Abstract: (3276 Views)
Background: Preterm birth is a leading cause of perinatal mortality and long-term morbidity as well as the long-term health consequences and cognitive outcomes.
Objective: Present study was conducted to determine prevalence and risk factors associated with preterm birth in Ardabil, Iran.
Materials and Methods: A case control study was conducted between Nov 2010 and July 2011 in all three maternal hospitals in Ardabil. All the live newborns during the study period were investigated. Of 6705 live births during the study period 346 births occurred in <37 weeks were taken as a case and 589 term neonates were taken as a control group. Data were obtained through review of prenatal and hospital delivery records. Univariate and multivariate logistic regression analysis were applied to obtain magnitude of association between independent variables and preterm birth.
Results: The prevalence rate of preterm birth was 5.1%. History of previous preterm birth (OR=12.7,CI: 3.9-40.4, p<0.001), hypertension (OR=7.3, CI:2.1-25.4, p=0.002), Oligohydramnios (OR=3.9, CI:1.6-9.5, p=0.002), spouse abuse (OR=3.7, CI:1.1-11.8, p=0.024), preeclampsia (OR=3.6, CI:1.3-10.3, p=0.014), premature rupture of membrane (OR=3.1, CI:1.9-4.9, p=0.000), bleeding or spotting during pregnancy (OR=2.0, CI:1.0-3.8, p=0.037), Hyperemesis Gravid arum (OR=2.0, CI: 1.1-3.8, p=0.015), urinary tract infection in 26-30 weeks , (OR=1. 8 CI:1.0-3.2, p=0.04), diastolic blood pressure ≤60 mmg (OR=1.5, CI: 0.99-2.2, p=0.049) were determined as significant risk factors for preterm birth.
Conclusion: Early detection and treatment of diseases or disorders among pregnant women especially hypertension, Oligohydramnios, preeclampsia, bleeding or spotting, Hyperemesis Gravid arum, urinary tract infection, and low diastolic blood pressure as well as the improving health care quality delivered to pregnant women may reduce preterm prevalence rate.
Objective: Present study was conducted to determine prevalence and risk factors associated with preterm birth in Ardabil, Iran.
Materials and Methods: A case control study was conducted between Nov 2010 and July 2011 in all three maternal hospitals in Ardabil. All the live newborns during the study period were investigated. Of 6705 live births during the study period 346 births occurred in <37 weeks were taken as a case and 589 term neonates were taken as a control group. Data were obtained through review of prenatal and hospital delivery records. Univariate and multivariate logistic regression analysis were applied to obtain magnitude of association between independent variables and preterm birth.
Results: The prevalence rate of preterm birth was 5.1%. History of previous preterm birth (OR=12.7,CI: 3.9-40.4, p<0.001), hypertension (OR=7.3, CI:2.1-25.4, p=0.002), Oligohydramnios (OR=3.9, CI:1.6-9.5, p=0.002), spouse abuse (OR=3.7, CI:1.1-11.8, p=0.024), preeclampsia (OR=3.6, CI:1.3-10.3, p=0.014), premature rupture of membrane (OR=3.1, CI:1.9-4.9, p=0.000), bleeding or spotting during pregnancy (OR=2.0, CI:1.0-3.8, p=0.037), Hyperemesis Gravid arum (OR=2.0, CI: 1.1-3.8, p=0.015), urinary tract infection in 26-30 weeks , (OR=1. 8 CI:1.0-3.2, p=0.04), diastolic blood pressure ≤60 mmg (OR=1.5, CI: 0.99-2.2, p=0.049) were determined as significant risk factors for preterm birth.
Conclusion: Early detection and treatment of diseases or disorders among pregnant women especially hypertension, Oligohydramnios, preeclampsia, bleeding or spotting, Hyperemesis Gravid arum, urinary tract infection, and low diastolic blood pressure as well as the improving health care quality delivered to pregnant women may reduce preterm prevalence rate.
Type of Study: Original Article |
References
1. Beck S, Wojdyla D, Say L, Betran AP, Merialdi M, Requejo JH, et al. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ 2010; 88: 31-38. [DOI:10.2471/BLT.08.062554]
2. Sonkusare S, Rai L, Naik P. preterm birth: mode of delivery and neonatal outcome. Med J Malaysia 2009; 64: 303-306.
3. Modarres SZ, Amooian B, Movahed SB, Mohamadi M. periodontal health in mothers of preterm and term infants. Taiwan J Obstet Gynecol 2007; 46: 157-161. [DOI:10.1016/S1028-4559(07)60010-2]
4. Goldenberg RL, Culhane JF, Jams JD, Rometo R. epidemiology and cause of preterm birth. Lancet 2008; 371: 75-83. [DOI:10.1016/S0140-6736(08)60074-4]
5. Renzo GCD, Giardina I, Rosati A, Clerici G, Torricelli M, Petraglia F, maternal risk factors for preterm birth: a country-based population analysis. Eur J Obstet Gynecol 2011; 3: 1-5. [DOI:10.1016/j.ejogrb.2011.09.024]
6. Mirzaie F, Mohammad-Alizadeh S. Contributing Factors of preterm delivery in parturient in a university hospital in Iran. Saudi Med J 2007; 28: 400-404.
7. Mahmoodi Z, Hoseini F, Sadeghi Avval Shahr H, Ghodsi Z, Amini L. The Association between Maternal Factors and Preterm Birth and Premature Rapture of Membranes. J Fam Reprod Health 2010; 4: 135-139.
8. Nabavizadeh SH, Malekzadeh M, Mousavizadeh A, Ghaffarian Shirazi HR, Ghaffari P, Karshenas N, et al. Retrospective study of Factors related to preterm labor in Yasuj, Iran. Int J Gen Med 2012: 2012: 1013-1017.
9. Raisanen S, Gissler M, Saari J, Kramer M, Heinonen S, Contribution of risk factors to Extremely, Very and Moderately Preterm Birts-Register-Based Analysis of 1,390.742 Singleton Births. PLOS One 2013; 8: 1-7. [DOI:10.1371/journal.pone.0060660]
10. Passini R, Tedesco R, Marba S, Cecatti J, Guinsburg R, Martinez F, et al. Brazilian multicenter study on prevalence of preterm birth and associated factors. BMC Pregnancy Childbirth 2010; 10: 1-7. [DOI:10.1186/1471-2393-10-22]
11. Murphy D. Epidemiology and environmental factors in preterm labor. Clin Obstet Gynecol 2007; 21: 773-789.
12. Chin LO C, Hsu JJ, Hsieh CC, Hsieh TT, Hung T. Risk factors for spontaneous preterm delivery before 34 weeks of gestation among Taiwanese women. Taiwan J Obstet Gynecol 2007; 46: 389-393. [DOI:10.1016/S1028-4559(08)60008-X]
13. Dolatian M, Mirabzadeh A, Forouzan AS, Sajjadi H, Alavi Majd H, Moafi F. Preterm Delivery and Psycho-Social Determinants of Health Based on World Health Organization Model in Iran: A Narrative Review. Glob J Health Sci 2013; 5: 52-64.
14. Cunningham FG, Leveno KJ, Hauth JC, edithors. Williams obstetrics. 23th Ed. New York, McGraw Hill; 2010.
15. Jafari F, Eftekhar H, Pourreza A, Mousavi J. Sosio-economic and medical determination of low birth weight in iran: 20 years after establishment of a primary health care network. Public Health 2010; 124: 153-157. [DOI:10.1016/j.puhe.2010.02.003]
16. Vallandares E, Ellsberg M, Pena R, Hogberg U, Persson LA. Physical partner abuse during pregnancy: a risk factor for low birth weight in Nicaragua. Obstet Gynecol 2002; 100: 700-704.
17. Vahdaninia M, Sadat S, Montazeri A. Correlation of low birth weight in term pregnancies: are Prospective study from Iran. BMC pregnancy childbirth 2008; 8: 1-5. [DOI:10.1186/1471-2393-8-12]
18. Warland J, MCcutcheon, Baghurst P. Maternal blood pressure in pregnancy and still birth: a case control study of third trimester still birth. AM J Perinatal 2008; 25: 311-317 [DOI:10.1055/s-2008-1075031]
19. Tan PC, Jacob R, Quek KF, Omar SZ. Pregnancy outcome in hyperemesis Gravidarum and the effect of laboratory clinical indicators of hyperemesis severity. J Obstet Gynacol 2007; 33: 457-464. [DOI:10.1111/j.1447-0756.2007.00552.x]
20. Nguyen N, Savitz DA, Thorp JM. Risk factors for preterm birth in Vietnam. Int J Gynaecol Obstet 2004; 86: 70-78. [DOI:10.1016/j.ijgo.2004.04.003]
21. Khalajinia Z, Jandaghi G. Maternal risk factors for preterm birth: a country-based population analysis. Eur J Obstet Gynecol Reprod Biol 2012; 159: 342-346.
22. Bernabe JV, Soriano T, Albaladejo R, Juarranz M, Calle ME, Martinez D, et al. Risk factors for low birth weight: a review. Eur J Obstet Gynecol Reprod Biol 2004; 116: 3-15. [DOI:10.1016/j.ejogrb.2004.03.007]
23. Coker AL, Sanderson M, Dong B, Partner violence during pregnancy and pregnancy outcomes. Paediatr Perinat Epidemiol 2004; 18: 260-290. [DOI:10.1111/j.1365-3016.2004.00569.x]
24. Rodrigues T, Rocha L, Barros H. Physical abuse during pregnancy and preterm delivery. AM J Obstet Gynecol 2008; 198: 1-6. [DOI:10.1016/j.ajog.2007.05.015]
25. Yost NP, Bloom SL, McIntire DD, Leveno KJ. A Prospective observational study of domestic violence during pregnancy. Obstet Gynecol 2005; 106: 61-65. [DOI:10.1097/01.AOG.0000164468.06070.2a]
26. Schoeman J, Grové DV, Odendaal HJ. Are domestic violence and the excessive use of alcohol risk factors for preterm birth. J Trop Pediatr 2005; 51: 49-50. [DOI:10.1093/tropej/fmh074]
27. Grimstad H, Schei B, Backe B, Jacobsen G. Physical abuse and low birth weight: a case-control study. J Obstet Gynecol 1997; 104: 1281-1287. [DOI:10.1111/j.1471-0528.1997.tb10975.x]
28. Cokkinides VE, Coker AL, Sanderson M, Addy C, Bethea L. Physical violence during pregnancy: maternal complications and birth outcomes. Obstet Gynecol 1999; 93: 661-666. [DOI:10.1097/00006250-199905000-00006]
29. Dodds L, Fell DB, Joseph KS, Allen VM, Butler B. Outcomes of pregnancies complicated by hyperemesis Gravidarum. Obstet Gynecol 2006; 107: 285-292. [DOI:10.1097/01.AOG.0000195060.22832.cd]
30. Hallak M, Tsalamandris K, Dombrowski MP, Isada NB, Pryde PG, Evans MI. Hyperemesis Gravidarum: effect on fetal outcome. J Repord Med 1996; 41: 871-874.
31. Roseboom TJ, Ravelli AC, van der Post JA, Painter RC. Maternal characteristics largely explain poor pregnancy outcome after hyperemesis Gravidarum. Eur J Obstet Gynecol Reprod Biol 2011; 156: 56-59. [DOI:10.1016/j.ejogrb.2011.01.010]
32. Veenendaal MV, van Abeelen AF, Painter RC, van der Post JA, Roseboom TJ. Consequences of hyperemesis Gravidarum for offspring: a systematic review and meta-analysis. BJOG 2011; 118: 1302-1313. [DOI:10.1111/j.1471-0528.2011.03023.x]
33. De Sutter P, Bontinck J, Schutysers V, Van der Elst J, Gerris J, Dhont M. First trimester bleeding and pregnancy outcome in singletons after assisted reproduction. Hum Reprod 2006; 21: 1907-1911. [DOI:10.1093/humrep/del054]
34. Strobino B, Pantel-Silverman J. Gestational vaginal bleeding and pregnancy outcome. Am J Epidemiol 1989; 129: 806-815. [DOI:10.1093/oxfordjournals.aje.a115195]
35. Schieve L, Handler A, Hershow R, Persky V, Davis F. Urinary tract infection during pregnancy: its association with maternal morbidity and perinatal outcome. Am J Public Health 1994; 84: 806-815. [DOI:10.2105/AJPH.84.3.405]
36. Zeitlin JA, Ancel PY, Saurel-Cubizolles MJ, Papiernik E. Are risk factors the same for small for gestational age versus other preterm birth. Am J Obstet Gynecol 2001; 185: 208-215. [DOI:10.1067/mob.2001.114869]
37. Krymko H, Bashiri A, Smolin A, Sheiner E, Bar-David J, Shoham-Vardi I, et al. Risk factors for recurrent preterm delivery. Eur J Obstet Gynecol Reprod Biol 2004; 113: 160-163. [DOI:10.1016/j.ejogrb.2003.08.006]
38. Wildschut HI, Nas T, Golding J. Are socio-demographic factors predictive of preterm birth? A reappraisal of the 1958 British perinatal mortality survey. Br J Obstet Gynaecol 1997; 104: 57-63. [DOI:10.1111/j.1471-0528.1997.tb10650.x]
39. Chen A, Basso O. Does low maternal blood pressure during pregnancy increase the risk of perinatal death? Epidemiology 2007; 18: 619-622. [DOI:10.1097/EDE.0b013e31812713e6]
40. Zhang J, Klebanoff MA. Low blood pressure during pregnancy and poor perinatal outcomes: an obstetric paradox. Am J Epidemiol 2001; 153: 642-646. [DOI:10.1093/aje/153.7.642]
41. Klosa W, Wilhelm C, Schillinger H, Hillemanns HG.Therapy of hypotension in pregnancy using norfenorfrine hydrochloride with special reference to the effects on fetal circulation-initial observation. Z Geburtshilfe Perinatol 1992; 196: 21-25.
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