پنجشنبه 13 دی 1403
[Archive]
دوره 6، شماره 3 - ( 4-1387 )
جلد 6 شماره 3 صفحات 0-77 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Khaki A A, Khaki A, Garachurlou S, Khorshidi F, Tajadini N, Madinei N. Pre and post natal exposure of 50 Hz electromagnetic fields on prostate glands of rats: an electron microscopy study. IJRM 2008; 6 (3) :77-0
URL: http://ijrm.ir/article-1-111-fa.html
URL: http://ijrm.ir/article-1-111-fa.html
Pre and post natal exposure of 50 Hz electromagnetic fields on prostate glands of rats: an electron microscopy study. International Journal of Reproductive BioMedicine. 1387; 6 (3) :77-0
چکیده: (3037 مشاهده)
Background: Men are unavoidably exposed to ambient electromagnetic fields (EMF) generated from various electrical gadgets and from power transmission lines. Prostate gland plays an important role in secretion of semen as largest accessory gland of male reproductive system. It seems that protection of this gland against EMF is important in spermatogenesis process.
Objective: The goal of this study was to investigate the effect of non ionizing radiation on ultra structure of prostate gland.
Materials and Methods: In total 50 male and 50 female rats, aged 15 weeks, were mated in animal house of Tabriz University of Medical Sciences. Then among born rats, 20 randomly were chosen as control and 30 were randomly chosen for exposure to EMF. They were exposed to 50 Hz EMF (8 M.T.) during in utero development (approximately 3 weeks) and postnatal life (5 weeks). Samples of prostate gland were processed and observed under light and transmission electron microscope.
Results: In the experimental group, the secretory epithelial cells were generally inactive and cuboidal and their nuclei were dense with more corpus amylace compared to the control. Smooth muscle fibers spread out in different directions with heterochromatic nuclei. Mitochondria seemed without cristae and electron opaque.
Conclusion: The results indicate that EMF had a deleterious effect on ultra structure of prostate gland in rat.
Objective: The goal of this study was to investigate the effect of non ionizing radiation on ultra structure of prostate gland.
Materials and Methods: In total 50 male and 50 female rats, aged 15 weeks, were mated in animal house of Tabriz University of Medical Sciences. Then among born rats, 20 randomly were chosen as control and 30 were randomly chosen for exposure to EMF. They were exposed to 50 Hz EMF (8 M.T.) during in utero development (approximately 3 weeks) and postnatal life (5 weeks). Samples of prostate gland were processed and observed under light and transmission electron microscope.
Results: In the experimental group, the secretory epithelial cells were generally inactive and cuboidal and their nuclei were dense with more corpus amylace compared to the control. Smooth muscle fibers spread out in different directions with heterochromatic nuclei. Mitochondria seemed without cristae and electron opaque.
Conclusion: The results indicate that EMF had a deleterious effect on ultra structure of prostate gland in rat.
نوع مطالعه: Original Article |
فهرست منابع
1. Bracken MB, Belanger K, Hellenbrand K, Dlugosz L, Holford TR, McSharry JE, et al. Exposure to electromagnetic fields during pregnancy with emphasis on electrically heated beds: association with birth weight and intrauterine growth retardation. Epidemiology 1995; 6: 263-270. [DOI:10.1097/00001648-199505000-00013]
2. Schreier N, Huss A, Roosli M. The prevalence of symptoms attributed to electromagnetic field exposure: a cross-sectional representative survey in Switzerland. Soz Praventivmed 2006; 51: 202-209. [DOI:10.1007/s00038-006-5061-2]
3. Juutilainen J, Matilainen P, Saarikoski S, Laara E, Suonio S. Early pregnancy loss and exposure to 50-Hz magnetic fields. Bioelectromagnetics 1993; 14: 229-236. [DOI:10.1002/bem.2250140306]
4. Dym M, Fawcett DW. The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Reprod 1970; 3: 308-326. [DOI:10.1093/biolreprod/3.3.308]
5. Forgacs Z, Somosy Z, Kubinyi G, Sinay H, Bakos J, Thuroczy G. Effects of whole-body 50-Hz magnetic field exposure on mouse Leydig cells. Scientific World Journal 2004; 4: s83-90. [DOI:10.1100/tsw.2004.182]
6. Khaki AA, Choudhry R, Kaul JK, Minaii B, Baybordi A, Oskuii G, et al. Effect of electromagnetic field on Sertoli cell of rat testes: a light and transmission electron microscope study. JIMSA 2004; 17: 136-140.
7. De Vita R, Cavallo D, Raganella L, Eleuteri P, Grollino MG, Calugi A. Effects of 50 Hz magnetic fields on mouse spermatogenesis monitored by flow cytometric analysis. Bioelectromagnetics 1995; 16: 330-334. [DOI:10.1002/bem.2250160510]
8. Khaki AA, Tubbs RS, Shoja MM, Rad JS, Khaki A, Farahani RM, et al. The effects of an electromagnetic field on the boundary tissue of the seminiferous tubules of the rat: A light and transmission electron microscope study. Folia Morphol (Warsz) 2006; 65: 188-194.
9. Lee JS, Ahn SS, Jung KC, Kim YW, Lee SK. Effects of 60 Hz electromagnetic field exposure on testicular germ cell apoptosis in mice. Asian J Androl 2004; 6: 29-34.
10. Gupta GS, Bawa SR. Secretory activities of prostates and seminal vesicles after localized x-irradiation of rat testes. J Reprod Fertil 1970; 21: 329-331. [DOI:10.1530/jrf.0.0210329]
11. Kotscher E, Voelkel O. Effects of estrogens and hypophyseal roentgen irradiation on the regenerative capacity of testes & seminal vesicles in rats. Wien Klin Wochenschr 1957; 69: 376-379.
12. McGivern RF, Sokol RZ, Adey WR. Prenatal exposure to a low frequency electromagnetic field demasculinizes adult scent marking behavior and increases accessory sex organ weights in rats. Teratology 1990; 41: 1-8. [DOI:10.1002/tera.1420410102]
13. Chan TW, Kressel HY. Prostate and seminal vesicles after irradiation: MR appearance. J Magn Reson Imaging 1991; 1: 503-511. [DOI:10.1002/jmri.1880010502]
14. Lacy D, Rotblat J. Study of the normal and irradiated boundary tissue of the seminiferous tubules of the rat. Exp Cell Res 1960; 21: 49-70. [DOI:10.1016/0014-4827(60)90346-3]
15. Leeson R, Leeson T. The postnatal development and differentiation of the boundary tissue of the seminiferous tubules of rat. Anat Rec 1964; 147: 243-249. [DOI:10.1002/ar.1091470208]
16. Lee JS, Ahn SS, Jung KC, Kim YW, Lee SK. Effects of 60 Hz electromagnetic field exposure on testicular germ cell apoptosis in mice. Asian J Androl 2004; 6: 29-34.
17. Marino AA, Reichmanis M, Becker RO, Ullrich B, Cullen JM. Power frequency electric field induces biological changes in successive generations of mice. Experientia 1980; 36:309-311. [DOI:10.1007/BF01952295]
18. Fernie KJ, Bird DM, Dawson RD, Lague PC. Effects of electromagnetic fields on the reproductive success of American kestrels. Physiol Biochem Zool 2000; 73:60-65. [DOI:10.1086/316726]
19. Freeman BA, Crapo JD. Biology of disease, free radicals and tissue injury. Lab Invest 1982; 47:412-426.
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
