Volume 8, Issue 1 (7-2010)                   IJRM 2010, 8(1): 24-28 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Soheilykhah S, Mogibian M, Rahimi-Saghand S, Rashidi M, Soheilykhah S, Piroz M. Incidence of gestational diabetes mellitus in pregnant women. IJRM 2010; 8 (1) :24-28
URL: http://ijrm.ir/article-1-171-en.html
1- Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , s_soheilykhah@yahoo.com
2- Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (2911 Views)
Background: Gestational Diabetes Mellitus (GDM) is the most common metabolic complications of pregnancy and causes fetal mortality and morbidity. Therefore early diagnosis of GDM is necessary to reduce maternal and fetal morbidity and to help prevent or delay the onset of type 2 diabetes
Objective: This prospective study was carried out to determine the incidence of GDM in Yazd and to assess the effect of various contributing factors. Materials and Methods: One thousand and seventy one pregnant women were screened for GDM at 24-28 weeks. Initial screening was done by a glucose challenge test with 50 g glucose. If the 1-hour blood glucose level exceeded 130 mg/dl then a 3-hour oral glucose tolerance test (OGTT) with 100g glucose was performed and diagnosis was established according to American Diabetes Association criteria.
Results: Three hundred and forty two (31.9%) women had an abnormal screening test and proceeded to oral glucose tolerance testing. The overall incidence of GDM was 10.2% (n=110). Seventy six of subjects (7.1%) have one abnormal OGTT. There was a significant association between incidence of GDM and age familial history of diabetes BMI before pregnancy parity history of GDM macrosomic baby still birth during previous pregnancies and systolic and diastolic blood pressure.
Conclusion: According to high incidence of GDM in our area we recommend screening for GDM in all pregnant women and modification of contributing factors in high risk women.
Full-Text [PDF 138 kb]   (670 Downloads) |   |   Full-Text (HTML)  (437 Views)  
Type of Study: Original Article |

References
1. Metzger BE, Buchanan TA, Coustan DR, de Leiva A, Dunger DB, Hadden DR, et al. Summary and recommendations of the fifth international workshop-conference on gestational diabetes mellitus. Diabetes Care 2007; 30: S 251.
2. Jovanovic L, Pettitt DJ. Gestational diabetes mellitus. JAMA 2001; 286: 2516-2518. [DOI:10.1001/jama.286.20.2516]
3. Kim C, Newton KM, Knopp RH. Gestational diabetes and the incidence of type 2 diabetes. Diabetes Care 2002; 25: 1862. [DOI:10.2337/diacare.25.10.1862]
4. Ferrara A, Hedderson MM, Quesenberry CP, Selby JV. Prevalence of gestational diabetes mellitus detected by the National Diabetes Data Group or the Carpenter and Coustan plasma glucose thresholds. Diabetes Care 2002; 25: 1625. [DOI:10.2337/diacare.25.9.1625]
5. American Diabetes Association. Gestational Diabetes Mellitus. Diabetes Care 2004; 27: S88-S90. [DOI:10.2337/diacare.27.2007.S88]
6. Di Cianni G, Volpe L, Lencioni C, Miccoli R, Cuccuru I, Ghio A, et al. Prevalence and risk factors for gestational diabetes assessed by universal screening. Diabetes research and clinical practice 2003; 62: 131-137. [DOI:10.1016/j.diabres.2003.07.004]
7. Zargar AH, Sheikh MI, Bashir MI, Masoodi SR, Laway BA, Wani AI, et al. Prevalence of gestational diabetes mellitus in Kashmiri women from the Indian subcontinent. Diabetes research and clinical practice 2004; 66: 139-145. [DOI:10.1016/j.diabres.2004.02.023]
8. Larijani B, Zahedi F. Epidemiology of diabetes mellitus in Iran. Iranian journal of Diabetes and Lipid disorders 2002; 1: 1-8.
9. Keshavarz M, Cheung NW, Babaee GR, Moghadam HK, Ajami ME, Shariati M. Gestational diabetes in Iran: incidence, risk factors and pregnancy outcomes. Diabetes research and clinical practice 2005; 69: 279-286. [DOI:10.1016/j.diabres.2005.01.011]
10. Shirazian N, Emdadi R, Mahboubi M, Motevallian A, Fazel-Sarjuei Z, Sedighpour N, et al. Screening for gestational diabetes: usefulness of clinical risk factors. Archives of Gynecology and Obstetrics 2009; 280: 933-937. [DOI:10.1007/s00404-009-1027-y]
11. Moses RG, Moses J, Davis WS. Gestational diabetes: do lean young Caucasian women need to be tested? Diabetes Care 1998; 21: 1803-1806. [DOI:10.2337/diacare.21.11.1803]
12. Yang X, Hsu-Hage B, Yu L, Simmons D. Selective screening for gestational diabetes in Chinese women. Diabetes Care 2002; 25:796. [DOI:10.2337/diacare.25.4.796]
13. Khine ML, Winklestein A, Copel JA. Selective screening for gestational diabetes mellitus in adolescent pregnancies. Obstet Gynecol 1999; 93: 738-742.
14. Jimenez-Moleon JJ, Bueno-Cavanillas A. Prevalence of gestational diabetes mellitus: variations related to screening strategy used. European Journal of Endocrinology 2002; 146: 831. [DOI:10.1530/eje.0.1460831]
15. Hadaegh F, Tohidi M, Harati H, Kheirandish M, Rahimi S. Prevalence of gestational diabetes mellitus in southern Iran (Bandar Abbas City). Endocrine Practice 2005; 11: 313-318. [DOI:10.4158/EP.11.5.313]
16. Jawad F, Irshaduddin PK. Prevalence of gestational diabetes and pregnancy outcome in Pakistan. Eastern Mediterranean Health Journal 1996; 2.
17. Naylor CD. Diagnosing gestational diabetes mellitus. Is the gold standard valid? Diabetes Care 1989; 12:565-572. [DOI:10.2337/diacare.12.8.565]
18. Zargar AH, Sheikh MI, Bashir MI, Masoodi SR, Laway BA, Wani AI, et al. Prevalence of gestational diabetes mellitus in Kashmiri women from the Indian subcontinent. Diabetes research and clinical practice 2004; 66: 139-145. [DOI:10.1016/j.diabres.2004.02.023]
19. Bjercke S, Dale PO, Tanbo T, Storeng R, Ertzeid G, byholm T. Impact of insulin resistance on pregnancy complications and outcome in women with polycystic ovary syndrome. Gynecol Obstet Invest 2002; 54: 94-98. [DOI:10.1159/000067719]
20. Jk Z, Dunaif A. Diagnostic criteria for polycystic ovary syndrome; towards a rational approach. In: Dunaif A, Givens JR and Haseltime F. Polycystic Ovary Syndrome, Boston: Blackwell Scientific; 1992; 377-384.
21. Jang HC, Min HK, Lee HK, Cho NH, Metzger BE. Short stature in Korean women: a contribution to the multifactorial predisposition to gestational diabetes mellitus. Diabetologia 1998; 41: 778-783. [DOI:10.1007/s001250050987]
22. Branchtein L, Schmidt MI, Matos MC, Yamashita T, Pousada JM, Duncan BB. Short stature and gestational diabetes in Brazil. Brazilian Gestational Diabetes Study Group. Diabetologia 2000; 43: 848. [DOI:10.1007/s001250051460]
23. Tabak AG, Kerenyi Z, Nagy E, Bosnyak Z, Madarasz E, Tamas G. Height and gestational diabetes mellitus. Diabetic Medicine 2002; 19: 344. [DOI:10.1046/j.1464-5491.2002.00712_1.x]

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb