Volume 2, Issue 2 (7-2004)                   IJRM 2004, 2(2): 70-73 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Dehghani Firouzabady R, Mehri Mahani I, Dehghani Firouzabady M. The Relation between the Position and Length of Uterus and Pregnancy Rate in IVF and Embryo Transfer Treatment Cycles. IJRM 2004; 2 (2) :70-73
URL: http://ijrm.ir/article-1-18-en.html
The Relation between the Position and Length of Uterus and Pregnancy Rate in IVF and Embryo Transfer Treatment Cycles
Razieh Dehghani Firouzabady * , Irandokht Mehri Mahani , Mehdi Dehghani Firouzabady
Abstract:   (2879 Views)
Background: Embryo transfer has received little clinical attention and has been the most inefficient step in in-vitro fertilization (IVF). Recent reports have suggested that an awareness of the position and length of the uterus during embryo transfer might be helpful in improving pregnancy rate. Objectives: The main objective of the present study was to determine the relation between the length and position of the uterus during embryo transfer and pregnancy rate. Materials and Methods: Patients were randomly allocated to two groups. In case group A (n=40) length of uterus was measured at the day of oocytes collection and the position of uterus was determined. In the control group, Group B, (n=40) the length and position of uterus were not investigated. The embryo transfer catheter was advanced to 5 mm from uterine fondues based on the previously determined cavity length in group A. The embryo transfer procedures ( IVF/ICSI) at 48 hours after oocytes collection was done. The outcome of the treatment cycle in two groups was investigated. Data analysis was performed by using chi-square, fisher-exact and ANOVA tests. The statistical significant was defined (P?0.05). Results: There were no significant differences in the mean age (28.5+4.4, 27.8+6.2), and duration of infertility (7+3.4, 8.7+5.4). The pregnancy rate was not significantly different with respect to position and length of uterus. The pregnancy rate in case groups was 25% and in control group was 22.5%, the difference was not significant (P= 0.792). In both groups, there were ectopic peregnancy and in fact he incidence of ectopic pregnancy, per reported clinical pregnancy, was highest in group A (14.9%) in comparison with group B (1.8%). Conclusion: The pregnancy rate was not significantly different in the two groups. Misdirecting the embryo transfer can not be avoided by an accurate knowledge of the position or length of uterine at the time of oocytes retrieval. Further studies are required to evaluate the role of length and position of uterus related to the pregnancy rate. Article
Keywords: Position, Length, Uterus, Embryo transfer, Pregnancy rate
Full-Text [PDF 144 kb]   (994 Downloads) |   |   Full-Text (HTML)  (299 Views)  
Type of Study: Original Article |
References
1. Agarwal, S.K., Coe, S. and Buyalos, P.R. (1994) The influence of uterine position on pregnancy rates with in vitro fertilization - embryo transfer. J. Assist. Repord. Genet., 11: 323-324. [DOI:10.1007/BF02215722] [PMID]
2. Edwards, R.G. and Beard, H.K. (1999) Is the success of human IVF more of genetics and evolution than growing blastocysts? Hum. Reprod. 14: 1-4. [DOI:10.1093/humrep/14.1.1] [PMID]
3. Egbase, P.E., Al Sharhan, M., Ing, R. et al. (1997) Pregnancy rates after intracytoplamic sperm injection in relation to sperm recovery techniques. J. Assist. Reprod. Genet., 14: 317-320. [DOI:10.1007/BF02765834] [PMID] [PMCID]
4. Eghase P.E., Al-sharhan M. and Grudzinskas J.G. Influence of position and length of uterus on implantation and clinical pregnancy. In IVF and embryo transfer treatment cycles. Hum Reprod, 15: 1943-1946. [DOI:10.1093/humrep/15.9.1943] [PMID]
5. Englert, Y., Puissant, F., Camus, M. et al. (1986) Clinical study on embryo transfer after human in vitro fertilization. J. In Vitro Fertile. Embryo Transfer, 3: 243-246. [DOI:10.1007/BF01132811] [PMID]
6. Frydman R. (2004). Clinical practice of embryo transfer: impaction implantation rates. J Cynecol Obstet Bio Reprod 33: S36-39.
7. Kovacs, G.T. (1999) What Factors are important for successful embryo transfer after in vitro fertilization? Hum. Reprod., 14: 590-592. [DOI:10.1093/humrep/14.3.590] [PMID]
8. Knutzen, V., Stratton, C.J., Sher G. et al. (1992) Mock Embryo transfer in early luteal phase, the cycle before in vitro fertilization and embryo transfer: a descriptive study. Fertil, Steril., 57: 156-162. [DOI:10.1016/S0015-0282(16)54793-1]
9. Lesny, P., Killick, S.R., Robinson, J. and Maguiness, S.D. (1999) Trnscervical embryo transfer as a risk factor for ectopic pregnancy. Fertil. Steril., 72: 305-309. [DOI:10.1016/S0015-0282(99)00226-5]
10. Lesny, P., Killick, S.R., Tetlow, R.L. et al. (1998) Embryo transfer _ can we learn anything new from the observation of junctional zone contractions? Hum. Repord., 13: 1540-1546. [DOI:10.1093/humrep/13.6.1540] [PMID]
11. Levi Setti P.E., Albani E., Cavagna M., Bulletti C., Colombo G.V. and Negril (2003). The impact of embryo transfer on implantation, placenta, Oct 24 Suppl,, S50-26. [DOI:10.1016/S0143-4004(03)00187-5]
12. Lewin, A., Schenker, J.G., Avrech, O. et al (1997) The role of uterine straightening by passive bladder distension before embryo transfer in IVF cycles. J. Assist. Reprod. Genet. 14: 32-34. [DOI:10.1007/BF02765749] [PMID] [PMCID]
13. Mansour, R., Aboulghar, M.A., Serour, G.I. et al (1994) Dummy embryo transfer using methylene blue. Hum. Reprod., 9: 1257-1259. [DOI:10.1093/oxfordjournals.humrep.a138690] [PMID]
14. Mirkin S., Jones E.L., Mayer J.F., Stadtmauer L., Gibbons W.E. and Oehniger S (2003). Impact of transabdominal ultrasound guidance on performance and outcome of transcervical uterine embryo transfer. J Assist Reprod Genet, 20; 318-322. [DOI:10.1023/A:1024809607966] [PMID] [PMCID]
15. Nazari, A., Askari, H.A., Check, J.H. and O'Shaughnessy. A. (1993) Embryo transfer technique as a cause of ectopic pregnancy in invitro fertilization. Fertil, Steril., 60: 919-921. [DOI:10.1016/S0015-0282(16)56297-9]
16. Tindall, V.R. (ed.) (1987) Jeffcoate's Principle of Gynaocology. 5th ed.:25-26. Butterworth-Heinemann, London.
17. Vaught, L.K., Stratton, C.J. Julain, P. et al. (1987) An improved system for catheter loading during embryo transfer. J. In vitro Fertile. Embryo. Transfer, 4: 346-348. [DOI:10.1007/BF01555384] [PMID]
18. Waterstone, J., Curson, R. and Parsons, J. (1991) Embryo transfer to low uterine cavity. Lancet, 337: 1413. [DOI:10.1016/0140-6736(91)93094-P]
19. Wood, E.G., Batzer, F.R., Go, K.J. et al. (2000) Ultrasound guided soft cather embryo transfer will improve pregnancy rates in in-vitro fertilization. Hum. Reprod., 15: 107-112. [DOI:10.1093/humrep/15.1.107] [PMID]
20. Woolcott, R. and Strenger, J. (1997) Potentially important variables indendified by trnasvaginal ultraound-guided embryo transfer. Hum Reprod., 12: 963-966. [DOI:10.1093/humrep/12.5.963] [PMID]
21. Yovich, J.L., Jturner, S.R. and Murphy, A.J. (1985) Embryo transfer technique as a cause of ectopic pregnancies in in-vitro fertilization. Fertil. Steril., 44: 318-321. [DOI:10.1016/S0015-0282(16)48854-0]
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb