International Journal of
Reproductive Biomedicine
Sun, Feb 2, 2025
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Volume 19, Issue 3 (March 2021)
IJRM 2021, 19(3): 255-260 |
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Gholami S, Namirnian N, Shukohifar M, Kalantari F, Azizi R. Maternal thyroid function test level during the first trimester of pregnancy at a center Yazd, Iran: A cross-sectional study. IJRM 2021; 19 (3) :255-260
URL: http://ijrm.ir/article-1-1817-en.html
URL: http://ijrm.ir/article-1-1817-en.html
Somaye Gholami1 
, Nasim Namirnian1 , Marzieh Shukohifar1 , Foroozandeh Kalantari2 , Reyhaneh Azizi * 3
, Nasim Namirnian1 , Marzieh Shukohifar1 , Foroozandeh Kalantari2 , Reyhaneh Azizi * 3
1- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Deputy for Health Affairs, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. ,Raihane.azizi@yahoo.com
2- Deputy for Health Affairs, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. ,
Abstract: (1568 Views)
Background: Thyroid dysfunction is associated with negative pregnancy outcomes. There is a lack of reliable information on thyroid hormones in Iranian pregnant women, especially in Yazd.
Objective: To determine the safe thyroid hormone levels in women of Yazd and also the first trimester-specific reference ranges for serum thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3).
Materials and Methods: In this cross-sectional study, the serum of 1,148 women in the first trimester of pregnancy was analyzed. Thyroid function tests (TSH, T4, T3) were measured through radioimmunoassay (RIA) [immunoradiometric (IRMA) for TSH]. The study was conducted in Yazd, from September 2018 to November 2019. Reference intervals were defined as the 5th, 50th, and 95th percentiles.
Results: The mean age of the participants was 28.78 (± 5.86 yr) (range: 15-45 yr). The thyroid hormones reference intervals in the first trimester were TSH (0.2-3.8 mIU/l), T4 (7.45-12.75, 𝜇g/dl), and T3 (100-217 ng/dl).
Conclusion: The results of the present study determined a local thyroid function measurement in the first trimester of pregnancy at a center of Yazd, Iran. This could facilitate the decision-making of maternal TSH level during the first trimester of pregnancy.
Objective: To determine the safe thyroid hormone levels in women of Yazd and also the first trimester-specific reference ranges for serum thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3).
Materials and Methods: In this cross-sectional study, the serum of 1,148 women in the first trimester of pregnancy was analyzed. Thyroid function tests (TSH, T4, T3) were measured through radioimmunoassay (RIA) [immunoradiometric (IRMA) for TSH]. The study was conducted in Yazd, from September 2018 to November 2019. Reference intervals were defined as the 5th, 50th, and 95th percentiles.
Results: The mean age of the participants was 28.78 (± 5.86 yr) (range: 15-45 yr). The thyroid hormones reference intervals in the first trimester were TSH (0.2-3.8 mIU/l), T4 (7.45-12.75, 𝜇g/dl), and T3 (100-217 ng/dl).
Conclusion: The results of the present study determined a local thyroid function measurement in the first trimester of pregnancy at a center of Yazd, Iran. This could facilitate the decision-making of maternal TSH level during the first trimester of pregnancy.
Type of Study: Original Article |
Subject:
Reproductive Endocrinology
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