Volume 20, Issue 1 (January 2022)                   IJRM 2022, 20(1): 13-20 | Back to browse issues page


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Azin F, Khazali H. Phytotherapy of polycystic ovary syndrome: A review. IJRM. 2022; 20 (1) :13-20
URL: http://ijrm.ssu.ac.ir/article-1-1878-en.html
1- Department of Animal Science and Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran. , f_azin@yahoo.com
2- Department of Animal Science and Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Abstract:   (688 Views)
Background: Polycystic ovary syndrome (PCOS) is a complex heterogeneous disease with various symptoms, which can affect females of reproductive age. Endocrine and metabolic abnormalities such as infertility, being over-weight or obese, type 2 diabetes, hyperandrogenism and increased luteinizing hormone (LH) are common in women with PCOS.
Objective: This review aimed to assess the efficacy of non-chemical and herbal substances for PCOS recovery. 
Materials and Methods: The keywords “non-chemical treatment”, “herbal treatment”, “polycystic ovary syndrome” and “PCOS” were used to search for articles in the electronic databases PubMed/MEDLINE, Web of Science, Scopus, and Reaxys, published from January 2009 to December 2019.
Results: 34 relevant studies were found and were briefly described in this review. The most effective herbal treatments in animal models of PCOS were to restore abnormality in serum sex steroid profile, LH: follicle stimulating hormone ratio, steroidogenic enzymes, cardiovascular parameters, lipid profile, and glucose and estrous cycles. In PCOS patients, positive effects on PCOS due to reductions in testosterone, estrogen, LH, LH: follicle stimulating hormone ratio, and insulin levels were observed.
Conclusion: The results of this review revealed the variability and efficacy of phytotherapy and non-chemical treatments associated with PCOS disease. These findings may help future studies on the etiology and treatment of this syndrome.
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Type of Study: Review Article | Subject: Reproductive Endocrinology

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