The Leptin concentrations in seminal plasma of men and its relationship to semen parameters

Jorsaraei, Seyed Gholam Ali; Shibahara, Hiroaki; , Ayustawati; Hirano, Yuki; Suzuki, Tatsuya; Tahmasbpour Marzony , Eisa; Zainalzadeh, Mahtab; Suzuki, Mitsuaki

دوره 8، شماره 3 - ( 4-1389 ) جلد 8 شماره 3 صفحات 100-95 | برگشت به فهرست نسخه ها

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Jorsaraei S G A, Shibahara H, Hirano Y, Suzuki T, Tahmasbpour Marzony E, Zainalzadeh M et al . The Leptin concentrations in seminal plasma of men and its relationship to semen parameters. IJRM 2010; 8 (3) :95-100
URL: http://ijrm.ir/article-1-188-fa.html

The Leptin concentrations in seminal plasma of men and its relationship to semen parameters. International Journal of Reproductive BioMedicine. 1389; 8 (3) :95-100

URL: http://ijrm.ir/article-1-188-fa.html

The Leptin concentrations in seminal plasma of men and its relationship to semen parameters

چکیده: (2826 مشاهده)

Background: Leptin is a polypeptide hormone secreted by white adipose tissue in proportion to body energy. Although the participation of leptin in female reproduction is well established any role in male reproductive function is at best tenuous.
Objective: The objective of this study was to compare the leptin concentration in human seminal plasma and then the relationships between seminal leptin and semen parameters were evaluated.
Materials and Methods: Semen samples were provided from 71 men; normozoospermic (n=22) asthenozoospermic (n=31) and oligoasthenozoospermic (n=18) referring to Jichi Medical University Hospital for in vitro fertilization-embryo transfer (IVF-ET) treatment. After liquefaction all sperm specimens were evaluated for sperm parameters and motility characteristics by computer-assisted semen analysis (CASA) system. After semen analysis concentrations of leptin in seminal plasma of all groups were measured by ELISA.
Results: The mean concentrations of leptin in seminal plasma of normozoospermic asthenozoospermic and oligoasthenozoospermic men were 0.75+/-0.09 ng/ml 0.8+/-0.14 ng/ml and 0.8+/-0.15 ng/ml respectively. A trend was observed for a lower leptin concentration in seminal plasma of normozoospermic men compared with asthenozoospermic and oligoasthenozoospermic men. There was a significant negative correlation between seminal plasma leptin concentration with sperm motility (p<0.05) and Curvilinear Velocity of the sperm kinetic parameter (p<0.01).
Conclusion: It was demonstrated that there was a significant correlation between seminal leptin with the sperm motility.

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نوع مطالعه: Original Article |

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