International Journal of
Reproductive Biomedicine
Thu, Apr 18, 2024
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Volume 19, Issue 9 (September 2021)
IJRM 2021, 19(9): 781-788 |
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Vahidi S, Zare Horoki A, Hashemi Talkhooncheh M, Jambarsang S, Dehghan Marvast L, Sadeghi A et al . Success rate and ART outcome of microsurgical sperm extraction in non obstructive azoospermia: A retrospective study. IJRM 2021; 19 (9) :781-788
URL: http://ijrm.ir/article-1-1909-en.html
URL: http://ijrm.ir/article-1-1909-en.html
Serajedin Vahidi1 
, Ali Zare Horoki1 , Mostafa Hashemi Talkhooncheh * 2, Sara Jambarsang3 , Laleh Dehghan Marvast4 , Ali Sadeghi5 , Samane Eskandarian4
, Ali Zare Horoki1 , Mostafa Hashemi Talkhooncheh * 2, Sara Jambarsang3 , Laleh Dehghan Marvast4 , Ali Sadeghi5 , Samane Eskandarian4
1- Department of Urology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , mhashemit2012@gmail.com
3- Department of Bio-Statistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4- Andrology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
5- Department of Surgical Technology, Faculty of Paramedical, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , mhashemit2012@gmail.com
3- Department of Bio-Statistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4- Andrology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
5- Department of Surgical Technology, Faculty of Paramedical, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (1278 Views)
Background: The management of non-obstructive azoospermia (NOA) disease relies on microdissection testicular sperm extraction (micro-TESE). Few studies have assessed the role of micro-TESE in men with NOA in our country.
Objective: The aim of the current study was to investigate the success rate of micro-TESE.
Materials and Methods: This retrospective descriptive-analytical study was conducted on 463 men with NOA in Yazd Reproductive Sciences Institute during September 2017 through September 2019. Sperm were retrieved and frozen according to the rapid sperm freezing protocol. After preparing the oocyte of the male partner’s spouse, sperms were thawed and then entered the intracytoplasmic sperm injection process. The clinical pregnancy of individuals was confirmed via ultrasound. Demographic data were extracted from medical records.
Results: The success rate of micro-TESE was 38% and successful fertilization, biochemical pregnancy, clinical pregnancy, and live birth were observed in 111 (85.4%), 29 (22.3%), 29 (22.3%) and 14 (10.7%) men, respectively. A significant difference was seen between the two groups, regarding age (p = 0.01). In addition, the mean follicle-stimulating hormone in men with positive micro-TESE was significantly lower than in men with negative micro-TESE (p = 0.02).
Conclusion: The success of pregnancy in couples with NOA managed via micro-TESE was significant. The study found that the success rate of micro-TESE was higher in older men and in those with lower follicle-stimulating hormone levels.
Objective: The aim of the current study was to investigate the success rate of micro-TESE.
Materials and Methods: This retrospective descriptive-analytical study was conducted on 463 men with NOA in Yazd Reproductive Sciences Institute during September 2017 through September 2019. Sperm were retrieved and frozen according to the rapid sperm freezing protocol. After preparing the oocyte of the male partner’s spouse, sperms were thawed and then entered the intracytoplasmic sperm injection process. The clinical pregnancy of individuals was confirmed via ultrasound. Demographic data were extracted from medical records.
Results: The success rate of micro-TESE was 38% and successful fertilization, biochemical pregnancy, clinical pregnancy, and live birth were observed in 111 (85.4%), 29 (22.3%), 29 (22.3%) and 14 (10.7%) men, respectively. A significant difference was seen between the two groups, regarding age (p = 0.01). In addition, the mean follicle-stimulating hormone in men with positive micro-TESE was significantly lower than in men with negative micro-TESE (p = 0.02).
Conclusion: The success of pregnancy in couples with NOA managed via micro-TESE was significant. The study found that the success rate of micro-TESE was higher in older men and in those with lower follicle-stimulating hormone levels.
Type of Study: Original Article |
Subject:
Reproductive Andrology
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