Volume 20, Issue 1 (January 2022)                   IJRM 2022, 20(1): 1-12 | Back to browse issues page

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Hosseini S E, Ilkhani M, Rohani C, Nikbakht Nasrabadi A, Ghanei Gheshlagh R, Moini A. Prevalence of sexual dysfunction in women with cancer: A systematic review and meta-analysis. IJRM 2022; 20 (1) :1-12
URL: http://ijrm.ir/article-1-2074-en.html
Prevalence of sexual dysfunction in women with cancer: A systematic review and meta-analysis
Seyedeh Esmat Hosseini1 , Mahnaz Ilkhani * 2, Camelia Rohani3 , Alireza Nikbakht Nasrabadi4 , Raza Ghanei Gheshlagh5 , Ashraf Moini6
1- Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2- Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Cancer Research Center, Shahid Beheshati University of Medical Sciences, Tehran, Iran. , m_ilkhani@yahoo.com
3- Department of Health Care Sciences, Palliative Care Center, Ersta Sköndal Bräcke University College, Campus Ersta, Stockholm, Sweden. Department of Community Health Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4- School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
5- Spiritual Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
6- Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran. Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. Department of Obstetrics and Gynecology, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:   (1647 Views)
Background: Cancer is one of the most common diseases and it has many physical and psychological consequences. Women with cancer are more likely to suffer from sexual dysfunction (SD) than healthy women.
Objective: To estimate the overall prevalence of SD in women with cancer.
Materials and Methods: The international databases Google Scholar, Embase, PubMed, Web of Science, and Scopus were searched for related articles without any time limitation. The keywords “Neoplasia”, “Tumor”, “Cancer”, “Malignancy”, “Female Sexual Function Index”, “FSFI”, and “female sexual dysfunction” along with their combinations were used in the search. Inconsistencies in the data were examined using the I2 test. The data were analyzed using the meta-analysis method and the random-effects model in the Stata software.
Results: The analysis of 24 articles with a sample size of 5483 women showed that the prevalence of SD in women with cancer was 66% (95% CI: 59-74%). The highest and lowest prevalence were in Africa and Europe, respectively (75%; 95% CI: 66-83% vs. 43%; 95% CI: 26-60%, respectively). There was no relationship between the prevalence of SD and the mean age of the women, sample size, year of publication, or quality of articles.
Conclusion: SD is highly prevalent in women with cancer. African and American women with cancer have a higher average FSD prevalence than Asian and European ones.
Keywords: Sexual dysfunction, Prevalence, Meta-analysis, Women, Sex.
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Type of Study: Review Article | Subject: Reproductive Oncology
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