International Journal of
Reproductive Biomedicine
Thu, Nov 21, 2024
[Archive]
Volume 20, Issue 7 (July 2022)
IJRM 2022, 20(7): 529-538 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Tabatabai R S, Asadi L, Mohammadi M, Rahmani M, Rezaeian E, Ghasemi F et al . Prenatal and clinical characteristics of pregnant women infected with COVID-19 in Yazd, Iran: A multicenter cross-sectional study. IJRM 2022; 20 (7) :529-538
URL: http://ijrm.ir/article-1-2260-en.html
URL: http://ijrm.ir/article-1-2260-en.html
Razieh Sadat Tabatabai1 
, Leila Asadi * 2, Maryam Mohammadi3 , Mina Rahmani1 , Elahe Rezaeian4 , Fatemeh Ghasemi5 , Mohammad Javad Tarahi6
, Leila Asadi * 2, Maryam Mohammadi3 , Mina Rahmani1 , Elahe Rezaeian4 , Fatemeh Ghasemi5 , Mohammad Javad Tarahi6
1- Department of Gynecology and Obstetrics, Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Department of Midwifery, Research Center for Infection Disease, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran. ,l_asadi66@yahoo.com
3- Department of Midwifery, Research Center for Nursing and Midwifery Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4- School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
5- Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
6- Departments of Epidemiology and Biostatistics, Isfahan University of Medical Sciences, Isfahan, Iran.
2- Department of Midwifery, Research Center for Infection Disease, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran. ,
3- Department of Midwifery, Research Center for Nursing and Midwifery Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4- School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
5- Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
6- Departments of Epidemiology and Biostatistics, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract: (1114 Views)
Background: Coronavirus infection has caused widespread concern among mothers and physicians about the health of pregnant women and infants.
Objective: The aim of this study was to evaluate the clinical and prenatal findings of pregnant women with coronavirus disease-2019 (COVID-19) virus.
Materials and Methods: The present study was a descriptive study that was conducted in 6 mother and child care centers. In this study, 81 pregnant women with COVID-19 admitted to centers in the period from March 2020-September 2020 were studied. Clinical and prenatal findings of the pregnant mothers were recorded using a data collection form with details of demographic characteristics and were analyzed.
Results: The gestational age of the affected women was between 4 and 40 wk. 48 deliveries were performed and 25% of deliveries were preterm. Coronavirus infection was the cause of termination of pregnancy in 4 cases. The most common symptoms of women when visiting the medical centers were: dry cough (58.0%), muscle pain and myalgia (56.8%) and fever (51.9%). The most common laboratory findings in the women were: increased C-reactive protein (67.90%), lymphopenia (18.51%), decreased white blood cells (27.16%), and increased liver enzymes (18.51%). Regarding the status of the newborns, out of the 33 neonates examined, 3 neonates were diagnosed with COVID-19.
Conclusion: The most common symptoms of pregnant women with COVID-19 are similar to those of other adults. In relation to neonatal infection, given that a number of the neonates tested positive, there appears to be evidence of vertical transmission, which requires further investigation.
Objective: The aim of this study was to evaluate the clinical and prenatal findings of pregnant women with coronavirus disease-2019 (COVID-19) virus.
Materials and Methods: The present study was a descriptive study that was conducted in 6 mother and child care centers. In this study, 81 pregnant women with COVID-19 admitted to centers in the period from March 2020-September 2020 were studied. Clinical and prenatal findings of the pregnant mothers were recorded using a data collection form with details of demographic characteristics and were analyzed.
Results: The gestational age of the affected women was between 4 and 40 wk. 48 deliveries were performed and 25% of deliveries were preterm. Coronavirus infection was the cause of termination of pregnancy in 4 cases. The most common symptoms of women when visiting the medical centers were: dry cough (58.0%), muscle pain and myalgia (56.8%) and fever (51.9%). The most common laboratory findings in the women were: increased C-reactive protein (67.90%), lymphopenia (18.51%), decreased white blood cells (27.16%), and increased liver enzymes (18.51%). Regarding the status of the newborns, out of the 33 neonates examined, 3 neonates were diagnosed with COVID-19.
Conclusion: The most common symptoms of pregnant women with COVID-19 are similar to those of other adults. In relation to neonatal infection, given that a number of the neonates tested positive, there appears to be evidence of vertical transmission, which requires further investigation.
Type of Study: Original Article |
Subject:
Pregnancy Health
References
1. Gorbalenya AE, Baker SC, Baric R, Groot RJ, Drosten C, Gulyaeva AA, et al. Severe acute respiratory syndrome-related coronavirus: The species and its viruses-a statement of the coronavirus study group. Nat Microbiol 2020; 5: 536-544. [DOI:10.1101/2020.02.07.937862]
2. Lai Ch-Ch, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents 2020; 55: 105924. [DOI:10.1016/j.ijantimicag.2020.105924] [PMID] [PMCID]
3. Jebril N. World Health Organization declared a pandemic public health menace: A systematic review of the coronavirus disease 2019 "COVID-19". Int J Psychosocial Rehabilit 2020; 24: 2784-2795. [DOI:10.2139/ssrn.3566298]
4. World Health Organization. Naming the coronavirus disease (COVID-19) and the virus that causes it. Braz J Implant Health Sci 2020; 2: 1-3.
5. Qiao J. What are the risks of COVID-19 infection in pregnant women? Lancet 2020; 395: 760-762. [DOI:10.1016/S0140-6736(20)30365-2]
6. Nikpouraghdam M, Farahani AJ, Alishiri Gh, Heydari S, Ebrahimnia M, Samadinia H, et al. Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in Iran: A single center study. J Clin Virology 2020; 127: 104378. [DOI:10.1016/j.jcv.2020.104378] [PMID] [PMCID]
7. Abdi M. Coronavirus disease 2019 (COVID-19) outbreak in Iran: Actions and problems. In: Mody L. Infection control & hospital epidemiology. USA: Combridge University Press; 2020. [DOI:10.1017/ice.2020.86] [PMID] [PMCID]
8. Zand AD, Heir AV. Environmental impacts of new Coronavirus outbreak in Iran with an emphasis on waste management sector. J Mater Cycles Waste Manag 2020; 23: 240-247. [DOI:10.1007/s10163-020-01123-1] [PMID] [PMCID]
9. Acker K, Eagen-Torkko M, Riley LE, Saiman L. COVID-19 infection, prevention, and control considerations in the obstetric environment. Clin Obstet Gynecol 2022; 65: 134-147. [DOI:10.1097/GRF.0000000000000666] [PMID] [PMCID]
10. Lotfi M, Hamblin MR, Rezaei N. COVID-19: Transmission, prevention, and potential therapeutic opportunities. Clinica Chimica Acta 2020; 508: 254-266. [DOI:10.1016/j.cca.2020.05.044] [PMID] [PMCID]
11. Chua MSQ, Lee JCS, Sulaiman S, Tan HK. From the frontlines of COVID‐19- How prepared are we as obstetricians: A commentary. BJOG 2020; 127: 786-788.
https://doi.org/10.1111/1471-0528.16254 [DOI:10.1111/1471-0528.16192]
12. Ahlers-Schmidt CR, Hervey AM, Neil T, Kuhlmann S, Kuhlmann Z. Concerns of women regarding pregnancy and childbirth during the COVID-19 pandemic. Patient Educ Couns 2020; 103: 2578-2582. [DOI:10.1016/j.pec.2020.09.031] [PMID] [PMCID]
13. Rasmussen SA, Hayes EB. Public health approach to emerging infections among pregnant women. Am J Public Health 2005; 95: 1942-1944. [DOI:10.2105/AJPH.2004.054957] [PMID] [PMCID]
14. Moore CA, Staples JE, Dobyns WB, Pessoa A, Ventura CV, Da Fonseca EB, et al. Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians. JAMA Pediatr 2017; 171: 288-295. [DOI:10.1001/jamapediatrics.2016.3982] [PMID] [PMCID]
15. Rasmussen SA, Jamieson DJ, Honein MA, Petersen LR. Zika virus and birth defects-reviewing the evidence for causality. N Engl J Med 2016; 374: 1981-1987. [DOI:10.1056/NEJMsr1604338] [PMID]
16. Haddad LB, Jamieson DJ, Rasmussen SA. Pregnant women and the Ebola crisis. N Engl J Med 2018; 379: 2492-2493. [DOI:10.1056/NEJMp1814020] [PMID]
17. Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: A report based on 116 cases. Am J Obstet Gynecol 2020; 223: 111. [DOI:10.1016/j.ajog.2020.04.014] [PMID] [PMCID]
18. Liu W, Wang J, Li W, Zhou Z, Liu S, Rong Z. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med 2020; 14: 193-198.
https://doi.org/10.3389/fmed.2020.00193 [DOI:10.1007/s11684-020-0772-y]
19. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet 2020; 395: 507-513. [DOI:10.1016/S0140-6736(20)30211-7]
20. Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal outcomes of pregnant women with coronavirus disease 2019 (COVID-19) pneumonia: A case-control study. Clin Infect Dis 2020; 71: 2035-2041. [DOI:10.1093/cid/ciaa352] [PMID] [PMCID]
21. Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, et al. Maternal death due to COVID-19. Am J Obstet Gynecol 2020; 223: 109. [DOI:10.1016/j.ajog.2020.04.030] [PMID] [PMCID]
22. Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children. J Infect 2020; 80: e7-e13. [DOI:10.1016/j.jinf.2020.03.007] [PMID] [PMCID]
23. Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, et al. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: A preliminary analysis. Am J Roentgenol 2020; 215: 127-132. [DOI:10.2214/AJR.20.23072] [PMID]
24. Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID‐19) on maternal, perinatal and neonatal outcome: Systematic review. Ultrasound Obstet Gynecol 2020; 56: 15-27.
https://doi.org/10.1002/uog.22088 [DOI:10.1002/uog.23059] [PMID] [PMCID]
25. Chen Y, Bai J. Maternal and infant outcomes of full-term pregnancy combined with COVID-2019 in Wuhan, China: Retrospective case series. Arch Gynecol Obstet 2020; 302: 545-551. [DOI:10.1007/s00404-020-05573-8] [PMID] [PMCID]
26. Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 2020; 9: 51-60. [DOI:10.21037/tp.2020.02.06] [PMID] [PMCID]
27. Chen H, Guo J, Wang Ch, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: A retrospective review of medical records. Lancet 2020; 395: 809-815. [DOI:10.1016/S0140-6736(20)30360-3]
28. Pereira A, Cruz-Melguizo S, Adrien M, Fuentes L, Marin E, Forti A, et al. Breastfeeding mothers with COVID-19 infection: A case series. Int Breastfeed J 2020; 15: 69. [DOI:10.1186/s13006-020-00314-8] [PMID] [PMCID]
29. Brown A, Shenker N. Experiences of breastfeeding during COVID‐19: Lessons for future practical and emotional support. Matern Child Nutr 2021; 17: e13088. [DOI:10.1111/mcn.13088]
30. Rodrigues C, Baía I, Domingues R, Barros H. Pregnancy and breastfeeding during COVID-19 pandemic: A systematic review of published pregnancy cases. Front Public Health 2020; 8: 558144. [DOI:10.3389/fpubh.2020.558144] [PMID] [PMCID]
31. Liu W, Wang Q, Zhang Q, Chen L, Chen J, Zhang B, et al. Coronavirus disease 2019 (COVID-19) during pregnancy: A case series. Preprints 2020: 2020020373.
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
