Volume 20, Issue 2 (February 2022)                   IJRM 2022, 20(2): 79-90 | Back to browse issues page

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Dashti S, Pejman A, Tabibnejad N, Mortezanasab M. The effect of transferring a poor-quality embryo together with a good-quality embryo on the singleton birth weight: A retrospective cohort study. IJRM. 2022; 20 (2) :79-90
URL: http://ijrm.ssu.ac.ir/article-1-2399-en.html
1- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , nasimtabibnejad@gmail.com
Abstract:   (526 Views)
Background: Embryo quality may affect birth weight among neonates born through assisted reproductive technology. There are very limited studies assessing the adverse effect of transferring a poor-quality embryo with a good-quality one on neonatal outcomes.
Objective: The aim of this study was to evaluate the effect of double embryo transfer (DET) with one good-quality embryo (GQE) plus a poor-quality one on the birth weight of newborns conceived by in vitro fertilization in both fresh and frozen-thawed embryo transfer cycles.
Materials and Methods: This study was conducted at Yazd Reproductive Sciences Institute, Yazd, Iran. A total of 626 women were classified into three groups according to the embryo quality: single embryo transfer with a GQE (group A); DET using two GQEs (group B); and DET using one good-quality and one poor-quality embryo (group C). The primary outcome was singleton birth weight which was compared between the three groups among fresh and frozen-embryo transfer cycles. A comparative analysis was also performed regarding the effect of vitrification procedures on neonatal birth weight within each of the three embryo quality-based groups.
Results: The mean birth weight and the rate of preterm birth were similar between the three groups (p = 0.45, and 0.32 respectively). There were also no significant differences found in the vitrification comparative analysis between and within the groups with regard to birth weight.
Conclusion: Our results showed that a poor-quality embryo did not have a significant influence on a good-quality one regarding neonatal birth weight when transferred together.
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Type of Study: Original Article | Subject: Embryology

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