International Journal of
Reproductive Biomedicine
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Volume 21, Issue 7 (July 2023)
Int J Reprod BioMed. 2023, 21(7): 551-556 |
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Baradaran Bagheri R, Bazrafkan M, Sabour A, Ataei M, Badehnoosh B, Mashak B, et al . The comparison of pregnancy outcomes in fresh and frozen embryo transfer: A cross-sectional study. Int J Reprod BioMed. 2023; 21 (7) :551-556
URL: http://ijrm.ir/article-1-2493-en.html
URL: http://ijrm.ir/article-1-2493-en.html
Ramesh Baradaran Bagheri *1 
, Mahshid Bazrafkan2 , Abbas Sabour3 , Mina Ataei4 , Bita Badehnoosh5 , Banafsheh Mashak6 , Bahareh Khakifirooz7 , Ramin Moghaddam8
, Mahshid Bazrafkan2 , Abbas Sabour3 , Mina Ataei4 , Bita Badehnoosh5 , Banafsheh Mashak6 , Bahareh Khakifirooz7 , Ramin Moghaddam8
1- Department of Obstetrics and Gynecology, Alborz University of Medical Sciences, Karaj, Iran. Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran. , dr.rameshbb@gmail.com
2- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
3- Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
4- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran. Department of Obstetrics and Gynecology, Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
5- Department of Obstetrics and Gynecology, Dietary Supplements and Probiotics Research Center, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
6- School of Medicine, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
7- Department of Obstetrics and Gynecology, School of Medicine, Kamali Hospital, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
8- International Academy of Health Sciences Informatics (IAHSI), Geneva, Switzerland., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
2- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
3- Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
4- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran. Department of Obstetrics and Gynecology, Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
5- Department of Obstetrics and Gynecology, Dietary Supplements and Probiotics Research Center, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
6- School of Medicine, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
7- Department of Obstetrics and Gynecology, School of Medicine, Kamali Hospital, Alborz University of Medical Sciences, Karaj, Iran., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
8- International Academy of Health Sciences Informatics (IAHSI), Geneva, Switzerland., Kamali Training Medical Center, Kamali St., Shohada Sq., Shahid Beheshti Ave., Karaj, Iran. Postal Code: 3155736179
Abstract: (2630 Views)
Background: The benefits of frozen embryo transfer (FET) vs. fresh embryo transfer for in vitro fertilization (IVF) have been discussed in previous studies.
Objective: To determine and compare the pregnancy outcomes following FET and frozen embryos transfer in women who underwent assisted reproductive techniques.
Materials and Methods: In this cross-sectional study, 233 women candidates for IVF/intra cytoplasmic sperm injection who referred to the Kamali Training Medical Center, Karaj, Iran during 2019-2020 were evaluated in 2 groups of fresh (n = 127) and frozen (n = 106) embryo transfers. The rates of pregnancy outcomes including chemical and clinical pregnancy, live birth, preeclampsia, ectopic pregnancy, still birth, and pregnancy loss were compared between groups in 3 age subgroups (< 25, 25-35, and 35-40 yr old).
Results: No significant difference in terms of chemical and clinical pregnancy and live birth rates were observed between groups in women aged < 25 yr. Chemical and clinical pregnancy and live birth rates were significantly higher in the FET group compared to fresh group in 25-35-yr-old women (p = 0.01, p = 0.03, and p = 0.01, respectively). In 35-40-yr-old women, no significant differences were observed in terms of chemical and clinical pregnancy rates, but live birth rate was found to be significantly higher in the FET group (p = 0.02). The pregnancy loss was lower in the FET group (p = 0.038).
Conclusion: In conclusion, the FET method in women aged 25-35 yr significantly increases the chance of successful IVF/intra cytoplasmic sperm injection.
Objective: To determine and compare the pregnancy outcomes following FET and frozen embryos transfer in women who underwent assisted reproductive techniques.
Materials and Methods: In this cross-sectional study, 233 women candidates for IVF/intra cytoplasmic sperm injection who referred to the Kamali Training Medical Center, Karaj, Iran during 2019-2020 were evaluated in 2 groups of fresh (n = 127) and frozen (n = 106) embryo transfers. The rates of pregnancy outcomes including chemical and clinical pregnancy, live birth, preeclampsia, ectopic pregnancy, still birth, and pregnancy loss were compared between groups in 3 age subgroups (< 25, 25-35, and 35-40 yr old).
Results: No significant difference in terms of chemical and clinical pregnancy and live birth rates were observed between groups in women aged < 25 yr. Chemical and clinical pregnancy and live birth rates were significantly higher in the FET group compared to fresh group in 25-35-yr-old women (p = 0.01, p = 0.03, and p = 0.01, respectively). In 35-40-yr-old women, no significant differences were observed in terms of chemical and clinical pregnancy rates, but live birth rate was found to be significantly higher in the FET group (p = 0.02). The pregnancy loss was lower in the FET group (p = 0.038).
Conclusion: In conclusion, the FET method in women aged 25-35 yr significantly increases the chance of successful IVF/intra cytoplasmic sperm injection.
Keywords: Assisted reproductive techniques, In vitro fertilization, Embryo transfer, Cryopreservation, Outcome assessment.
Type of Study: Original Article |
Subject:
Fertility & Infertility
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