Volume 21, Issue 8 (August 2023)                   IJRM 2023, 21(8): 647-656 | Back to browse issues page


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Asemi-Rad A, Heidari Z, Mahmoudzadeh-Sagheb H, Mehdipour Y, Moudi B, Sheibak N et al . Prevalence of congenital anomalies and related factors in live births in Zahedan, Southeast of Iran: A cross-sectional study. IJRM 2023; 21 (8) :647-656
URL: http://ijrm.ir/article-1-2730-en.html
1- Department of Anatomical Sciences, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Cellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
2- Department of Histology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.
3- Department of Histology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran , histology@ymail.com
4- Department of Health Information Technology, School of Paramedical Sciences, Torbat Heydarieh University of Medical Sciences, Torbat Heydarieh, Iran.
5- Department of Histology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran
6- Department of Histology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
7- Department of Health Information Technology, Zahedan University of Medical Sciences, Zahedan, Iran.
Abstract:   (282 Views)
Background: The term congenital anomalies (CAs) refer to structural or functional abnormalities at the time of conception. Approximately 12 deaths related to congenital disabilities occur in every 10,000 babies born.
Objective: This study aimed to evaluate the prevalence and associated factors of single and multiple CAs in live births in Zahedan, Southeast Iran.
Materials and Methods: This cross-sectional study was conducted on 59,087 live births in a referral hospital in Zahedan located in the southeast of Iran during 2009-2019. All live births were examined by pediatricians and the CAs and categorized based on the international classification of diseases.
Results: Of 59,085 live births, at least 883 had a significant anomaly, and the prevalence rate of CAs was about 149 per 10,000. Anomalies of the nervous (24.1%) and cardiovascular systems (21.10%) were the most frequent, occurring in 213 and 187 of the live births, respectively. Spina bifida is the most common anomaly of the central nervous system. The most common anomalies in the cardiovascular system were unspecified heart malformations (17.1%), cardiovascular malformations (18.7%), and patent ductus arteriosus (11.7%). Significant correlations were found between the parent's consanguinity marriage, the mother's age, an existing anomaly in the family, and relatives in single and multiple CAs (p = 0.02, p = 0.02, p < 0.001, p = 0.01, respectively).
Conclusion: The prevalence of CAs was 149 per 10,000 live births. The highest prevalence of CAs was related to the central nervous system. Increasing the public's knowledge about fetal defects can reduce the prevalence of CAs.
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Type of Study: Original Article | Subject: Perinatology

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