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Cancer still is the most challenging disease globally, despite fascinating advances in medicine. Those types that assault reproductive-related organs are among cancers with a higher death rate, and the numbers are overgrowing. Therefore, early detection of cancers is the best way to a most functional treatment and/or inhibition of the progress. Current cancer detection strategies predominantly suffer from low sensitivity and specificity and need expensive instruments with an expert operator. However, biosensors have shown a promising ability to detect/quantify molecular biomarkers associated with Cancer's early stages over the past decades. They can be very sensitive and selective, especially biosensors using nanomaterials and nanostructures, called nanobiosensors. Biosensors are categorized based on their transducer types, and they can be in various working platforms from electrode and lab tubes to papers and chips. Later called lab-on-a-chip devices, a biosensor is integrated into a microfluidics chip and can do sample handling and manipulation before detection. Here, I introduce biosensors, their types and platforms, and their applications to detect reproductive-related cancers.

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