Volume 19, Issue 5 (Suppl- 2021)                   IJRM 2021, 19(5): 259-259 | Back to browse issues page

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Koohpeyma F, Mahmoodi M, Saki F, Ranjbar Omrani G, Mazloom Z. P-92 The effects of soy milk enriched with lactobacillus casei on the sexual hormone in ovariectomized rats. IJRM 2021; 19 (5) :259-259
URL: http://ijrm.ir/article-1-2899-en.html
1- Endocrine and Metabolism Research Center, Shiraz University of Medical Science, Shiraz, Iran.
2- Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. , marzieh.mahmoodi123@gmail.com
3- Department of Clinical Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract:   (269 Views)
Background: Loss of ovarian function causes estrogen deficiency, followed by menopause and uterine atrophy.
Objective: The aim of the present study was to investigate the effects of soy milk Enriched with Lactobacillus casei on the sexual hormone, as hormonal replacement therapy in ovariectomized (OVX) rats.
Materials and Methods: Fifty female Sprague Dawley rats were randomly assigned into 5 sets: control, sham-operated, OVX, OVX + soy milk, and OVX + soy milk + Lactobacillus casei groups. The soy milk and Lactobacillus casei were fed to OVX groups at the concentration of (1 × 109 CFU/ml/day) for 4 wk. Finally, the rate of serum estradiol and progesterone was measured using Elisa reader and the data were analyzed using the SPSS statistical software (V. 23) and Tukey test.
Results: The results showed a significant decrease in serum estradiol, progesterone, in the OVX group compared to the control and sham groups (p < 0.05). On the other hand, all the treated groups significantly increased the serum estradiol, progesterone, compared to the OVX group (p < 0.001).
Conclusion: The results indicated that soy milk Enriched with Lactobacillus casei ameliorate the changes arising from ovariectomy on the sexual hormone as hormonal replacement therapy when ovarian hormones are absent.
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Type of Study: Congress Abstract | Subject: Fertility & Infertility

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