چهارشنبه 7 آبان 1404
[Archive]
دوره 19، شماره 5 - ( 3-1400 )
جلد 19 شماره 5 صفحات 180-180 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Adib Rad H, Basirat Z, Mostafazadeh A, Faramarzi M, Bijani A, Aghajanpour-Mir S. P-13 The role of HLA-G in recurrent pregnancy loss: A case-control study. IJRM 2021; 19 (5) :180-180
URL: http://ijrm.ir/article-1-2911-fa.html
URL: http://ijrm.ir/article-1-2911-fa.html
P-13 The role of HLA-G in recurrent pregnancy loss: A case-control study. International Journal of Reproductive BioMedicine. 1400; 19 (5) :180-180
چکیده: (461 مشاهده)
Background: Human leukocyte antigen (HLA)-G is the main molecule for maternal acceptance of the semi-allogenic fetus by adjusting the maternal immune system in the pregnancy.
Objective: The aim of this study was to determine the role of sHLA-G in recurrent pregnancy loss (RPL) in North of Iran.
Materials and Methods: This case-control study was done on two different groups including 40 women with recurrent miscarriage, and 40 non-pregnant healthy women. Soluble HLA-G (sHLA-G) levels were measured using a BioVendor sHLA-G ELISA kit.
Results: Findings show that women with recurrent abortion had significantly higher sHLA-G concentrations than fertile women (mean ± SD: 220.62 ± 223.48 u/ml and 87.77 ± 91.65 u/ml, respectively p < 0.0001, Mann-Whitney test).
Conclusion: There is many argumentation about the role of HLA-G in the pregnancy and RPL. Therefore document in this context remains obscure. So it can be concluded that sHLA-G may not act in the implantation of the embryo, but its role in the preservation of maternal tolerance to fetus, because serum sHLA-G level increased in the after abortion and postpartum in both women who had recurrent spontaneous abortion and normal vaginal delivery.
Objective: The aim of this study was to determine the role of sHLA-G in recurrent pregnancy loss (RPL) in North of Iran.
Materials and Methods: This case-control study was done on two different groups including 40 women with recurrent miscarriage, and 40 non-pregnant healthy women. Soluble HLA-G (sHLA-G) levels were measured using a BioVendor sHLA-G ELISA kit.
Results: Findings show that women with recurrent abortion had significantly higher sHLA-G concentrations than fertile women (mean ± SD: 220.62 ± 223.48 u/ml and 87.77 ± 91.65 u/ml, respectively p < 0.0001, Mann-Whitney test).
Conclusion: There is many argumentation about the role of HLA-G in the pregnancy and RPL. Therefore document in this context remains obscure. So it can be concluded that sHLA-G may not act in the implantation of the embryo, but its role in the preservation of maternal tolerance to fetus, because serum sHLA-G level increased in the after abortion and postpartum in both women who had recurrent spontaneous abortion and normal vaginal delivery.
نوع مطالعه: Congress Abstract |
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
