پنجشنبه 8 آبان 1404
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دوره 19، شماره 5 - ( 3-1400 )
جلد 19 شماره 5 صفحات 287-287 |
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Nabi A, Torki A, Anbari F. P-120 The effect of different O-antigen serogroups of Escherichia coli on infertility in semen samples of fertile and infertile men. IJRM 2021; 19 (5) :287-287
URL: http://ijrm.ir/article-1-3031-fa.html
URL: http://ijrm.ir/article-1-3031-fa.html
P-120 The effect of different O-antigen serogroups of Escherichia coli on infertility in semen samples of fertile and infertile men. International Journal of Reproductive BioMedicine. 1400; 19 (5) :287-287
چکیده: (389 مشاهده)
Background: Male genital tract infections have been associated with infertility. Among the types of bacteria, Escherichia coli (E. coli) has drawn increasing attentions. However, its role in male infertility remains undefined.
Objective: This investigation aimed to characterize and compare the distributions of O-antigen serogroups of E. coli in the semen samples of fertile and infertile men.
Materials and Methods: In this case control study, semen samples were collected from 575 fertile and 1725 infertile men. The E. coli-positive samples were evaluated in term of concentration, morphology, viability and motility parameters according to World Health Organization 2010 guidelines. Finally, different serogroups of E. coli were identified by multiplex polymerase chain reaction targeting the O-antigen variations of the bacterium.
Results: The prevalence of E. coli among fertile men was significantly higher than infertile men (p < 0.0001). The sperm morphology, viability and motility, in the E. coli-positive fertile group was significantly higher than in the E. coli-positive infertile group (p < 0.0001). The E. coli O6 was the most prevalent serogroup found in both groups. However, there was no significant difference in frequencies of different serogroups of E. coil between two groups (p = 0.55).
Conclusion: Despite the higher prevalence of E. coli among fertile men, the E. coli have more detrimental effect on semen parameters in infertile men. There was no association between the types of E. coli serogroups between two groups.
Objective: This investigation aimed to characterize and compare the distributions of O-antigen serogroups of E. coli in the semen samples of fertile and infertile men.
Materials and Methods: In this case control study, semen samples were collected from 575 fertile and 1725 infertile men. The E. coli-positive samples were evaluated in term of concentration, morphology, viability and motility parameters according to World Health Organization 2010 guidelines. Finally, different serogroups of E. coli were identified by multiplex polymerase chain reaction targeting the O-antigen variations of the bacterium.
Results: The prevalence of E. coli among fertile men was significantly higher than infertile men (p < 0.0001). The sperm morphology, viability and motility, in the E. coli-positive fertile group was significantly higher than in the E. coli-positive infertile group (p < 0.0001). The E. coli O6 was the most prevalent serogroup found in both groups. However, there was no significant difference in frequencies of different serogroups of E. coil between two groups (p = 0.55).
Conclusion: Despite the higher prevalence of E. coli among fertile men, the E. coli have more detrimental effect on semen parameters in infertile men. There was no association between the types of E. coli serogroups between two groups.
نوع مطالعه: Congress Abstract |
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