International Journal of
Reproductive Biomedicine
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Volume 22, Issue 4 (April 2024)
Int J Reprod BioMed. 2024, 22(4): 283-294 |
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Ethics code: IR.IUMS.REC.1400.1173
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Ranjbar F, Haghani S, Aghashahi M, Gharacheh M. Changes in menstrual cycles among Iranian women during the COVID-19 pandemic: A cross-sectional study. Int J Reprod BioMed. 2024; 22 (4) :283-294
URL: http://ijrm.ir/article-1-3293-en.html
URL: http://ijrm.ir/article-1-3293-en.html
1- Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran., Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Rashid Yasemi St., Valiasr Ave., Tehran, Iran. P.O. Box: 19395-4798
2- School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran., Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Rashid Yasemi St., Valiasr Ave., Tehran, Iran. P.O. Box: 19395-4798
3- Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran. ,gharacheh.m@gmail.com
2- School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran., Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Rashid Yasemi St., Valiasr Ave., Tehran, Iran. P.O. Box: 19395-4798
3- Nursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran. ,
Abstract: (1849 Views)
Background: Some women experienced alterations in their menstrual cycles during the Coronavirus disease 2019 (COVID-19) pandemic.
Objective: This study aimed to evaluate the changes in menstrual cycles among Iranian women during the COVID-19 pandemic.
Materials and Methods: This cross-sectional study included 1500 women of childbearing age referred to healthcare centers in Tehran, Iran from April-November 2022. Participants were selected using the stratified sampling method. Data were collected via a questionnaire covering information on menstrual cycle, COVID-19 infection, and COVID-19 vaccination status. The study's outcomes focused on menstrual changes by evaluating cycle regularity, duration, and symptoms based on participant-reported observations.
Results: The findings revealed that the pattern of menstrual change during the pandemic occurred in the form of a shorter interval in 8.6%, and longer interval in 8.9%, shorter duration in 10.4%, longer duration in 9.4%, heavier bleeding in 12.3%, lighter bleeding in 14.7%. The chance of menstrual changes in women who were infected with COVID-19 was 54% higher than that of women who were not infected, and the chance of menstrual changes in women who received 3 doses of COVID-19 vaccine was 1.5 times higher than women who had not been vaccinated.
Conclusion: Our research revealed a high incidence of menstrual changes among Iranian women of childbearing age during the COVID-19 pandemic. Healthcare providers should be knowledgeable about the menstrual changes associated with COVID-19 infection and vaccination to provide information and support to affected women.
Objective: This study aimed to evaluate the changes in menstrual cycles among Iranian women during the COVID-19 pandemic.
Materials and Methods: This cross-sectional study included 1500 women of childbearing age referred to healthcare centers in Tehran, Iran from April-November 2022. Participants were selected using the stratified sampling method. Data were collected via a questionnaire covering information on menstrual cycle, COVID-19 infection, and COVID-19 vaccination status. The study's outcomes focused on menstrual changes by evaluating cycle regularity, duration, and symptoms based on participant-reported observations.
Results: The findings revealed that the pattern of menstrual change during the pandemic occurred in the form of a shorter interval in 8.6%, and longer interval in 8.9%, shorter duration in 10.4%, longer duration in 9.4%, heavier bleeding in 12.3%, lighter bleeding in 14.7%. The chance of menstrual changes in women who were infected with COVID-19 was 54% higher than that of women who were not infected, and the chance of menstrual changes in women who received 3 doses of COVID-19 vaccine was 1.5 times higher than women who had not been vaccinated.
Conclusion: Our research revealed a high incidence of menstrual changes among Iranian women of childbearing age during the COVID-19 pandemic. Healthcare providers should be knowledgeable about the menstrual changes associated with COVID-19 infection and vaccination to provide information and support to affected women.
Type of Study: Original Article |
Subject:
Fertility & Infertility
References
1. Danesh L, Amini A, Aslam I, Mensah-Djan A. The effects of SARS-CoV-2 on menstruation. Reprod Biomed Online 2021; 43: 769. [DOI:10.1016/j.rbmo.2021.08.014] [PMID] [PMCID]
2. Kwak Y, Kim Y, Baek KA. Prevalence of irregular menstruation according to socioeconomic status: A population-based nationwide cross-sectional study. PloS One 2019; 14: e0214071. [DOI:10.1371/journal.pone.0214071] [PMID] [PMCID]
3. Bruinvels G, Blagrove RC, Goldsmith E, Shaw L, Martin D, Piasecki J. How lifestyle changes during the COVID-19 global pandemic affected the pattern and symptoms of the menstrual cycle. Int J Environ Res Public Health 2022; 19: 13622. [DOI:10.3390/ijerph192013622] [PMID] [PMCID]
4. Yuksel B, Ozgor F. Effect of the COVID‐19 pandemic on female sexual behavior. Int J Gynaecol Obstet 2020; 150: 98-102. [DOI:10.1002/ijgo.13193] [PMID] [PMCID]
5. Nguyen BT, Pang RD, Nelson AL, Pearson JT, Benhar Noccioli E, Reissner HR, et al. Detecting variations in ovulation and menstruation during the COVID-19 pandemic, using real-world mobile app data. PloS One 2021; 16: e0258314. [DOI:10.1371/journal.pone.0258314] [PMID] [PMCID]
6. Ozimek N, Velez K, Anvari H, Butler L, Goldman KN, Woitowich NC. Impact of stress on menstrual cyclicity during the Covid-19 pandemic: A survey study. J Women's Health 2021; 31: 84-90. [DOI:10.1089/jwh.2021.0158] [PMID]
7. Demir O, Sal H, Comba C. Triangle of COVID, anxiety and menstrual cycle. J Obstet Gynaecol 2021; 41: 1257-1261. [DOI:10.1080/01443615.2021.1907562] [PMID]
8. Takmaz T, Gundogmus I, Okten SB, Gunduz A. The impact of COVID‐19‐related mental health issues on menstrual cycle characteristics of female healthcare providers. J Obstet Gynaecol Res 2021; 47: 3241-3249. [DOI:10.1111/jog.14900] [PMID] [PMCID]
9. Medina-Perucha L, López-Jiménez T, Holst AS, Jacques-Aviñó C, Munrós-Feliu J, Martínez-Bueno C, et al. Self-reported menstrual alterations during the COVID-19 syndemic in Spain: A cross-sectional study. Int J Womens Health 2022; 14: 529-544. [DOI:10.2147/IJWH.S354655] [PMID] [PMCID]
10. Li K, Chen G, Hou H, Liao Q, Chen J, Bai H, et al. Analysis of sex hormones and menstruation in COVID-19 women of child-bearing age. Reprod Biomed Online 2021; 42: 260-267. [DOI:10.1016/j.rbmo.2020.09.020] [PMID] [PMCID]
11. Male V. Menstrual changes after covid-19 vaccination. BMJ 2021; 15: 374. [DOI:10.1136/bmj.n2211] [PMID]
12. Alvergne A, Kountourides G, Argentieri MA, Agyen L, Rogers N, Knight D, et al. A retrospective case-control study on menstrual cycle changes following COVID-19 vaccination and disease. iScience 2023; 26: 106401. [DOI:10.1016/j.isci.2023.106401] [PMID] [PMCID]
13. Muhaidat N, Alshrouf MA, Azzam MI, Karam AM, Al-Nazer MW, Al-Ani A. Menstrual symptoms after COVID-19 vaccine: A cross-sectional investigation in the MENA region. Int J Womens Health 2022; 14: 395-404. [DOI:10.2147/IJWH.S352167] [PMID] [PMCID]
14. Laganà AS, Veronesi G, Ghezzi F, Ferrario MM, Cromi A, Bizzarri M, et al. Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey. Open Med 2022; 17: 475-484. [DOI:10.1515/med-2022-0452] [PMID] [PMCID]
15. Sharp GC, Fraser A, Sawyer G, Kountourides G, Easey KE, Ford G, et al. The COVID-19 pandemic and the menstrual cycle: Research gaps and opportunities. Int J Epidemiol 2022; 51: 691-700. [DOI:10.1093/ije/dyab239] [PMID] [PMCID]
16. Rastegar T, Feryduni L, Fakhraei M. COVID-19 vaccine side effects on menstrual disturbances among Iranian women. New Microbes New Infect 2023; 53: 101114. [DOI:10.1016/j.nmni.2023.101114] [PMID] [PMCID]
17. Samani RO, Hashiani AA, Razavi M, Vesali S, Rezaeinejad M, Maroufizadeh S, et al. The prevalence of menstrual disorders in Iran: A systematic review and meta-analysis. Int J Reprod BioMed 2018; 16: 665-678.
18. Mihm M, Gangooly S, Muttukrishna S. The normal menstrual cycle in women. Anim Reprod Sci 2011; 124: 229-236. [DOI:10.1016/j.anireprosci.2010.08.030] [PMID]
19. Al-Najjar MA, Al-Alwany RR, Al-Rshoud FM, Abu-Farha RK, Zawiah M. Menstrual changes following COVID-19 infection: A cross-sectional study from Jordan and Iraq. Plos One 2022; 17: e0270537. [DOI:10.1371/journal.pone.0270537] [PMID] [PMCID]
20. Bucciarelli V, Nasi M, Bianco F, Seferovic J, Ivkovic V, Gallina S, et al. Depression pandemic and cardiovascular risk in the COVID-19 era and long COVID syndrome: Gender makes a difference. Trends Cardiovasc Med 2022; 32: 12-17. [DOI:10.1016/j.tcm.2021.09.009] [PMID] [PMCID]
21. Im JH, Je YS, Baek J, Chung M-H, Kwon HY, Lee J-S. Nutritional status of patients with COVID-19. Int J Infect Dis 2020; 100: 390-393. [DOI:10.1016/j.ijid.2020.08.018] [PMID] [PMCID]
22. Gorji A, Ghadiri MK. Potential roles of micronutrient deficiency and immune system dysfunction in the coronavirus disease 2019 (COVID-19) pandemic. Nutrition 2021; 82: 111047. [DOI:10.1016/j.nut.2020.111047] [PMID] [PMCID]
23. Edelman A, Boniface ER, Benhar E, Han L, Matteson KA, Favaro C, et al. Association between menstrual cycle length and coronavirus disease 2019 (COVID-19) vaccination: A US cohort. Obstet Gynecol 2022; 139: 481-489. [DOI:10.1097/AOG.0000000000004695] [PMID] [PMCID]
24. Matar SG, Nourelden AZ, Assar A, Bahbah EI, Alfryjat AM, Hasabo EA, et al. Effect of COVID‐19 vaccine on menstrual experience among females in six Arab countries: A cross-sectional study. Influenza Other Respir Viruses 2023; 17: e13088.
25. Kurdoğlu Z. Do the COVID-19 vaccines cause menstrual irregularities? Int J Womens Health Reprod Sci 2021; 9: 158-159. [DOI:10.15296/ijwhr.2021.29]
26. Taşkaldıran I, Vuraloğlu E, Bozkuş Y, Turhan İyidir Ö, Nar A, Başçıl Tütüncü N. Menstrual changes after COVID-19 infection and COVID-19 vaccination. Int J Clin Pract 2022; 2022: 3199758. [DOI:10.1155/2022/3199758] [PMID] [PMCID]
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