دوره 11، شماره 8 - ( 8-1392 )                   جلد 11 شماره 8 صفحات 0-637 | برگشت به فهرست نسخه ها

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Oremosu A A, Akang E N, Adigwe C C, Okoko I E, Azu O O. Post-treatment with Telfairia occidentalis seed oil attenuates alcohol-induced testicular damage in Sprague-Dawley rats. IJRM 2013; 11 (8) :637-0
URL: http://ijrm.ir/article-1-454-fa.html
درمان با روغن دانه Telfairia occidentalis باعث کاهش آسیب  های ایجاد شده به وسیله الکل در بیضه رت های Sprague-Dawley می شود . International Journal of Reproductive BioMedicine. 1392; 11 (8) :637-0

URL: http://ijrm.ir/article-1-454-fa.html

درمان با روغن دانه Telfairia occidentalis باعث کاهش آسیب  های ایجاد شده به وسیله الکل در بیضه رت های Sprague-Dawley می شود 
چکیده:   (3134 مشاهده)
مقدمه: گزارش شده که استفاده طولانی مدت الکل باعث اختلالات جنسی در مردان از جمله کاهش میزان تستوسترون و همچنین تغییرات مرفولوژی بیضه می­شود.
هدف: هدف از انجام این تحقیق بررسی توانایی Telfairia occidentalis (T.O.) در بهبود اثرات الکل بر روی پارامترهای بیضه بود.
مواد و روش­ها: رت­های Sprague- Dawley نر به 6 گروه تقسیم شدند. گروه کنترل+ آب مقطر برای 8 هفته آب مقطر، گروه کنترل- برای 2 هفته اتانول و سپس 6 هفته آب مقطر دریافت کردند. گروه دیگر برای 2 هفته اتانول و گروه بعدی 2 هفته اتانول و سپس برای 6 هفته mg/kg 600 و 400، 200 T.O. دریافت کردند.
نتایج: اتانول باعث کاهش واضح ژرم سل­های بیضه بعد از 2 هفته شد. T.O. در مقایسه با گروه کنترل در روز mg/kg 200 اثر مشخصی نداشت اما در روز mg/kg 400 T.O. با برگرداندن اثرات اتانول باعث افزایش تعداد و حرکت اسپرم، تستوسترون سرم و وزن بیضه شد. در نهایت در روز mg/kg 600 کاهش ژرم سل­های بیضه و یک کاهش در پارامترهای سمن و وزن بیضه مشاهده شد.
نتیجه­گیری: این مطالعه نشان داد که T.O. باعث تحریک بازسازی ژرم سل­های بیضه و بهبود کیفیت سمن در یک روز مشخص شده و همچنین T.O. توانایی برگشت دادن آسیب­های بیضه بر اثر اتانول را دارد. 
واژه‌های کلیدی: Telfairia occidentalis، بیضه، سمیت اتانول، تعداد اسپرم، پس از درمان.
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نوع مطالعه: Original Article |
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