Volume 12, Issue 12 (12-2014)                   IJRM 2014, 12(12): 811-0 | Back to browse issues page

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Rahiminejad M E, Moaddab A, Rabiee S, Esna-Ashari F, Borzouei S, Hosseini S M. The relationship between clinicobiochemical markers and depression in women with polycystic ovary syndrome. IJRM 2014; 12 (12) :811-0
URL: http://ijrm.ir/article-1-498-en.html
The relationship between clinicobiochemical markers and depression in women with polycystic ovary syndrome
Mohammad Ehsan Rahiminejad * 1, Amirhossein Moaddab2 , Soghra Rabiee3 , Farzaneh Esna-Ashari4 , Shiva Borzouei5 , Seyyed Mohammad Hosseini6
1- Research Center of Behavioral Sciences and Dependency, Hamedan University of Medical Sciences, Hamedan, Iran , me_rahiminejad21@yahoo.com
2- Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA
3- Department of Obstetrics and Gynecology, Hamedan University of Medical Sciences, Hamedan, Iran
4- Department of Community Medicine, Hamedan University of Medical Sciences, Hamedan, Iran
5- Department of Internal Medicine, Hamedan University of Medical Sciences, Hamedan, Iran
6- Research Center of Behavioral Sciences and Dependency, Hamedan University of Medical Sciences, Hamedan, Iran
Abstract:   (2519 Views)
Background: Previous studies have demonstrated that clinical features of 16TPolycystic ovary syndrome16T (PCOS) are associated with a lower degree of health, self, and sex satisfaction.
Objective: Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS.
Materials and Methods: In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in a complementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV (DSMIV-TR) criteria.
Results: Among the study participants, 82 women (68.3%) were non-depressed, and 38 patients (31.7%) had some degrees of depression. According to the psychiatric interview, 10 patients (8.3%) had major depression, 22 patients (18.3%) had minor depression and 6 patients (5%) had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance (HOMA-IR) between depressed and non-depressed subjects (p>0.05). Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects (-0.139≤r≤+0.121, p>0.05).
Conclusion: In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression.
Keywords: Polycystic ovary syndrome, Depression, Obesity, Hirsutism, Complication
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