Volume 4, Issue 2 (7-2006)                   IJRM 2006, 4(2): 51-56 | Back to browse issues page

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Atashkhoii S, Abdollahi S, Ghasemzad Dejani A, Farzadi L. Conscious sedation with and without paracervical block for transvaginal ultrasonically guided oocyte collection: A comparison of the pain and sedation levels, and postoperative side effects. IJRM 2006; 4 (2) :51-56
URL: http://ijrm.ir/article-1-55-en.html
Conscious sedation with and without paracervical block for transvaginal ultrasonically guided oocyte collection: A comparison of the pain and sedation levels, and postoperative side effects
Simin Atashkhoii * , Sedige Abdollahi , Aliye Ghasemzad Dejani , Laya Farzadi
Abstract:   (1873 Views)
Background: The quality of intraoperative analgesia with paracervical block (PCB) during egg collection in in-vitro fertilization (IVF) is still unclear. Objective: This study performed to compare the pain levels during egg collection and the subsequent intra and postoperative side effects in patients receiving a conscious sedation with and without paracervical block.
Materials and methods: In this prospective, double-blind, and placebo–controlled study, 60 patients undergoing egg collection in their first IVF cycle were randomized to receive conscious sedation in conjunction with paracervical block with 10 ml lidocaine 1.5% (sedation + PCB patients or study group) or with 10 ml normal saline (sedation patients or placebo group).
Results: Patients in study group experienced significantly less vaginal (10.40±8.40 mm vs 20.77±4.60 mm respectively; p<0.0005) and abdominal pain (10.87±5.08 mm vs 35.33±4.27 mm respectively; p<0.0005) during egg collection, compared with those in placebo group. Propofol requirements was 8.67±2.42 mg in PCB patients vs 25.60±5.29 mg in placebo group (p<0.0005). Incidence of intraoperative (9.90% vs 50% respectively; p=0.002) and postoperative (3.33% vs 56.66% respectively; p<0.0005) side effects were significantly less in study patients compared with placebo group.
Conclusion: Conscious sedation with PCB appears to be an effective and safe method of providing analgesia and anesthesia for transvaginal retrieval of oocyte.
Keywords: Transvaginal egg collection, Conscious sedation, Paracervical block, Pain relief
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Type of Study: Original Article |
References
1. Lewin A, Laufer N, Rabinowitz R, Magalioth E, Bar I, Scheker J. Ultrasonically guided oocyte collection under local anesthesia: The first choice method in vitro fertilzation-a comparative study with laparoscopy. Fertil Steril 1986;46:257-261. [DOI:10.1016/S0015-0282(16)49522-1]
2. Ng Yu HE, Tang OS, Chi Chui DK, Chung HP. A prospective, randomized, doule-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF. Hum Repord 1999;14:2783-2787. [DOI:10.1093/humrep/14.11.2783] [PMID]
3. Trout SW, Vallerand Ap, Kemmann E. Conscious sedation for in vitro fertilization. Fertil Steril 1998;69:799-808. [DOI:10.1016/S0015-0282(98)00031-4]
4. Brindson PR. In vitro fertilization and assisted reproduction. New York Partenon 1999;2nd ed:171-173.
5. Soussis I, Boyd D, Paraschos T, Duffy S, Bower S, Troughton P, et al. Follicular fluid levels of midazolam, Fentanyl, and alfentanil during transvaginal Oocyte retrieval. Fertil Steril 1995;64:1003-1007. [DOI:10.1016/S0015-0282(16)57919-9]
6. Ng Yu HE, Chi Chui DK, Tang OS, Chung HP. Paracervical block with and without conscious sedation: a comparison of the pain levels during egg collection and the postoperative side effects. Fertil Steril 2001;15:711-717. [DOI:10.1016/S0015-0282(01)01693-4]
7. Wiener-Kronish JP, Grapper M.A. Conscious sedation. Philadelphia, Hanley and Belfus 2001; 1st ed: 51-57,60-61,135-142.
8. Jaffe RA, Samuels SI. Anesthesiologist's manual of surgical procedures. New York, Lippincott Williams and Wilkins 1999; 2nd ed: 584-588.
9. Elkington NM, Kehoe J, Acharga U. Intravenous sedation in assisted conception units: a UK survey. Hum Fertil (camb) 2003; 6: 74-76. [DOI:10.1080/1464770312331369083] [PMID]
10. Wilhelm W, Hammadeh ME, White PF, George T, Fleser R, Biedler A. General anesthesia versus monitored anesthesia care with remifentanil for assisted reproductive technologies: effect on pregnancy rate. J Clin Anesth 2002;14: 1-5. [DOI:10.1016/S0952-8180(01)00331-2]
11. Hong JY, Kang IS, Koony MK, Yoon HJ, Jee YS, Park JW et al. Preoperactive anxiety and propofol requirement in conscious sedation for ovum retrieval. J Korean Med Sci 2003;18:863-868. [DOI:10.3346/jkms.2003.18.6.863] [PMID] [PMCID]
12. Ng Yu HE, Tang OS, Chi Chui DK, Chung HP. Comparison of two different doses of lidocaine used in paracervical block during Oocyte collection in an IVF program. Hum Reprod 2000;15:2148-2151. [DOI:10.1093/humrep/15.10.2148] [PMID]
13. Speroff L, Fritz MA. Clinical gynecologic endocrinology and infertility. Phyladelphia, Lipincott Williams and Wilkins2005;7th ed:1228-1229.
14. Miller RD. Anesthesia. Phyladelphia, Churchil Livingstone 2000;5th ed:228-256,332,506-507.
15. Casati A, Valentini G, Zangrillo A, Senatore R, Airaghi B, Torri G. Anesthesia for ultrasound guided oocyte retrieval: midazolam/remifentanil versus propofol/fentanyl regimens. Eur J Anesthesiol 1999;16:773-778. [DOI:10.1097/00003643-199911000-00005]
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